ENSDARG00000054707


Danio rerio

Features
Gene ID: ENSDARG00000054707
  
Biological name :dhx8
  
Synonyms : DEAH (Asp-Glu-Ala-His) box polypeptide 8 / dhx8
  
Possible biological names infered from orthology : A2A4P0 / ATP-dependent RNA helicase DHX8 / DEAH-box helicase 8 / Q14562
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 27569125
Gene end: 27588341
  
Corresponding Affymetrix probe sets: Dr.512.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000066281
Ensembl peptide - ENSDARP00000143624
NCBI entrez gene - 606595     See in Manteia.
RefSeq - XM_002663947
RefSeq - XM_021480343
swissprot - E7F7E3
swissprot - A0A286Y8Y8
ZFIN ID - ZDB-GENE-050809-39
Ensembl - ENSDARG00000054707
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DHX8ENSGALG00000032305Gallus gallus
 DHX8ENSG00000067596Homo sapiens
 Dhx8ENSMUSG00000034931Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dhx16 / DEAH (Asp-Glu-Ala-His) box polypeptide 16 / O60231* / DEAH-box helicase 16*ENSDARG0000001315037
dhx38 / DEAH (Asp-Glu-Ala-His) box polypeptide 38 / Q92620* / DEAH-box helicase 38*ENSDARG0000010001336
dhx15 / DEAH (Asp-Glu-Ala-His) box helicase 15 / O35286* / O43143* / DEAH-box helicase 15* / Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 *ENSDARG0000001539231
dhx33 / DEAH (Asp-Glu-Ala-His) box polypeptide 33 / Q80VY9* / Q9H6R0* / DEAH-box helicase 33* / Putative ATP-dependent RNA helicase DHX33 *ENSDARG0000005178526
dhx40 / DEAH (Asp-Glu-Ala-His) box polypeptide 40 / Q6PE54* / Q8IX18* / DEAH-box helicase 40* / Probable ATP-dependent RNA helicase DHX40 *ENSDARG0000004158624
dhx34 / DEAH (Asp-Glu-Ala-His) box polypeptide 34 / Q14147* / DExH-box helicase 34*ENSDARG0000006116821
DHX35 / zgc:158828 / Q9H5Z1* / DEAH-box helicase 35* / probable ATP-dependent RNA helicase DHX35 isoform b *ENSDARG0000006341918


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR003029  S1 domain
 IPR007502  Helicase-associated domain
 IPR011545  DEAD/DEAH box helicase domain
 IPR011709  Domain of unknown function DUF1605
 IPR012340  Nucleic acid-binding, OB-fold
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR022967  RNA-binding domain, S1
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IBA
 biological_processGO:0051301 cell division IMP
 biological_processGO:0060215 primitive hemopoiesis IMP
 biological_processGO:0070054 mRNA splicing, via endonucleolytic cleavage and ligation IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005681 spliceosomal complex IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism dead , abnormal
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 ZFA:0001117 post-vent region post-vent region curved , abnormal
post-vent region increased curvature , abnormal
Show

 ZFA:0009000 cell cell mitotic spindle disorganized , abnormal
Show

 ZFA:0009044 blood cell blood cell absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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