ENSDARG00000015176


Danio rerio

Features
Gene ID: ENSDARG00000015176
  
Biological name :ror1
  
Synonyms : receptor tyrosine kinase-like orphan receptor 1 / ror1
  
Possible biological names infered from orthology : Inactive tyrosine-protein kinase transmembrane receptor ROR1 / Q01973 / Q9Z139
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 31772182
Gene end: 31987940
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000135258
Ensembl peptide - ENSDARP00000118145
NCBI entrez gene - 568282     See in Manteia.
RefSeq - XM_005165885
swissprot - F1QKB5
swissprot - A0A0R4IMU5
ZFIN ID - ZDB-GENE-030131-6104
Ensembl - ENSDARG00000015176
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ROR1ENSGALG00000011019Gallus gallus
 ROR1ENSG00000185483Homo sapiens
 Ror1ENSMUSG00000035305Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ror2 / receptor tyrosine kinase-like orphan receptor 2 / Q01974* / Q9Z138*ENSDARG0000007622752
igf1ra / insulin-like growth factor 1a receptor / IGF1R* / P08069* / insulin like growth factor 1 receptor*ENSDARG0000002742320
ntrk3b / neurotrophic tyrosine kinase, receptor, type 3b / NTRK3* / Q16288* / neurotrophic receptor tyrosine kinase 3*ENSDARG0000008621419
insra / insulin receptor a / INSR* / P06213* / P15208* / insulin receptor* / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta*ENSDARG0000001194819
ntrk2b / neurotrophic tyrosine kinase, receptor, type 2b / NTRK2* / Q16620* / P15209* / BDNF/NT-3 growth factors receptor * / neurotrophic receptor tyrosine kinase 2*ENSDARG0000009851119
igf1rb / insulin-like growth factor 1b receptor / IGF1R* / P08069* / insulin like growth factor 1 receptor*ENSDARG0000003443419
insrb / insulin receptor b / INSR* / P06213* / P15208* / insulin receptor* / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta*ENSDARG0000007152419
ntrk2a / neurotrophic tyrosine kinase, receptor, type 2a / NTRK2* / Q16620* / P15209* / BDNF/NT-3 growth factors receptor * / neurotrophic receptor tyrosine kinase 2*ENSDARG0000005989718
ntrk3a / neurotrophic tyrosine kinase, receptor, type 3a / NTRK3* / Q16288* / Q6VNS1* / NT-3 growth factor receptor * / neurotrophic receptor tyrosine kinase 3*ENSDARG0000007722818
ntrk1 / neurotrophic tyrosine kinase, receptor, type 1 / P04629* / Q3UFB7* / neurotrophic receptor tyrosine kinase 1* / High affinity nerve growth factor receptor *ENSDARG0000000458617
alk / ALK receptor tyrosine kinase / P97793* / Q9UM73* / ALK tyrosine kinase receptor *ENSDARG0000009583316
ltk / leukocyte receptor tyrosine kinase / P08923* / P29376* / Leukocyte tyrosine kinase receptor *ENSDARG0000004286116
ddr2l / discoidin domain receptor family, member 2, likeENSDARG0000010383016
ddr2b / discoidin domain receptor tyrosine kinase 2b / DDR2* / Q16832* / Q62371* / Discoidin domain-containing receptor 2 * / discoidin domain receptor tyrosine kinase 2*ENSDARG0000005869515
ddr2a / discoidin domain receptor tyrosine kinase 2a / DDR2* / Q16832* / Q62371* / Discoidin domain-containing receptor 2 * / discoidin domain receptor tyrosine kinase 2*ENSDARG0000010069315
ddr1 / discoidin domain receptor tyrosine kinase 1 / Q03146* / Q08345* / Epithelial discoidin domain-containing receptor 1 *ENSDARG0000007852315
ptk7a / protein tyrosine kinase 7a / PTK7* / Q13308* / Q8BKG3* / Inactive tyrosine-protein kinase 7 * / protein tyrosine kinase 7 (inactive)*ENSDARG0000001186313
ros1 / c-ros oncogene 1 , receptor tyrosine kinase / P08922* / Q78DX7* / Proto-onco tyrosine-protein kinase ROS * / ROS proto-oncogene 1, receptor tyrosine kinase*ENSDARG0000008719712
musk / muscle, skeletal, receptor tyrosine kinase / Q61006* / O15146* / muscle associated receptor tyrosine kinase* / Muscle, skeletal receptor tyrosine-protein kinase *ENSDARG000000987644
LT631676.1ENSDARG000001117430


Protein motifs (from Interpro)
Interpro ID Name
 IPR000001  Kringle
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR013806  Kringle-like fold
 IPR016247  Tyrosine-protein kinase, receptor ROR
 IPR018056  Kringle, conserved site
 IPR020067  Frizzled domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
WNT5A-dependent internalization of FZD2, FZD5 and ROR2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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