ENSGALG00000011019


Gallus gallus

Features
Gene ID: ENSGALG00000011019
  
Biological name :ROR1
  
Synonyms : receptor tyrosine kinase like orphan receptor 1 / ROR1
  
Possible biological names infered from orthology : Inactive tyrosine-protein kinase transmembrane receptor ROR1 / Q01973 / Q9Z139
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 27993878
Gene end: 28122891
  
Corresponding Affymetrix probe sets: Gga.9476.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044620
Ensembl peptide - ENSGALP00000054152
Ensembl peptide - ENSGALP00000017932
NCBI entrez gene - 395179     See in Manteia.
RefSeq - XM_015290942
RefSeq - NM_204509
RefSeq - XM_015290940
RefSeq - XM_015290941
RefSeq Peptide - NP_989840
swissprot - A0A1D5PMR5
swissprot - F1NML5
swissprot - A0A1D5NW84
Ensembl - ENSGALG00000011019
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ror1ENSDARG00000015176Danio rerio
 ROR1ENSG00000185483Homo sapiens
 Ror1ENSMUSG00000035305Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ROR2 / receptor tyrosine kinase like orphan receptor 2 / Q01974* / Q9Z138*ENSGALG0000001520856
MUSK / muscle, skeletal receptor tyrosine protein kinase precursor / O15146* / Q61006* / muscle associated receptor tyrosine kinase* / Muscle, skeletal receptor tyrosine-protein kinase *ENSGALG0000001572822
IGF1R / insulin-like growth factor 1 receptor precursor / P08069* / insulin like growth factor 1 receptor*ENSGALG0000004065120
NTRK2 / Q91987 / BDNF/NT-3 growth factors receptor / P15209* / Q16620* / neurotrophic receptor tyrosine kinase 2*ENSGALG0000001259420
INSR / insulin receptor / P06213* / P15208* / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta*ENSGALG0000004075819
NTRK3 / Q91044 / NT-3 growth factor receptor / Q16288* / Q6VNS1* / neurotrophic receptor tyrosine kinase 3*ENSGALG0000004024119
NTRK1 / high affinity nerve growth factor receptor precursor / P04629* / Q3UFB7* / neurotrophic receptor tyrosine kinase 1* / High affinity nerve growth factor receptor *ENSGALG0000001901919
INSRR / insulin receptor related receptor / P14616* / Q9WTL4* / Insulin receptor-related protein Insulin receptor-related protein alpha chain Insulin receptor-related protein beta chain*ENSGALG0000001325318
ROS1 / ROS proto-oncogene 1, receptor tyrosine kinase / P08922* / Q78DX7* / Proto-onco tyrosine-protein kinase ROS *ENSGALG0000001491316
DDR1 / Q03146* / Q08345* / discoidin domain receptor tyrosine kinase 1* / Epithelial discoidin domain-containing receptor 1 *ENSGALG0000000861616
LTK / leukocyte receptor tyrosine kinase / P08923* / P29376* / Leukocyte tyrosine kinase receptor *ENSGALG0000000861516
DDR2 / discoidin domain receptor tyrosine kinase 2 / Q16832* / Q62371* / Discoidin domain-containing receptor 2 *ENSGALG0000003932215
PTK7 / inactive tyrosine-protein kinase 7 precursor / Q8BKG3* / Q13308* / Inactive tyrosine-protein kinase 7 * / protein tyrosine kinase 7 (inactive)*ENSGALG0000000860914
ALK* / P97793* / Q9UM73* / ALK receptor tyrosine kinase* / ALK tyrosine kinase receptor *ENSGALG0000000903412


Protein motifs (from Interpro)
Interpro ID Name
 IPR000001  Kringle
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR013806  Kringle-like fold
 IPR016247  Tyrosine-protein kinase, receptor ROR
 IPR018056  Kringle, conserved site
 IPR020067  Frizzled domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0048839 inner ear development IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 cellular_componentGO:0043679 axon terminus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0017147 Wnt-protein binding IEA
 molecular_functionGO:0042813 Wnt-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
WNT5A-dependent internalization of FZD2, FZD5 and ROR2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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