ENSGALG00000008609


Gallus gallus

Features
Gene ID: ENSGALG00000008609
  
Biological name :PTK7
  
Synonyms : inactive tyrosine-protein kinase 7 precursor / PTK7
  
Possible biological names infered from orthology : Inactive tyrosine-protein kinase 7 / protein tyrosine kinase 7 (inactive) / Q13308 / Q8BKG3
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 4399060
Gene end: 4424446
  
Corresponding Affymetrix probe sets: Gga.2218.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051294
Ensembl peptide - ENSGALP00000014004
NCBI entrez gene - 421257     See in Manteia.
RefSeq - XM_015283375
RefSeq - NM_001031035
RefSeq Peptide - NP_001026206
swissprot - A0A1D5PET5
swissprot - F1NLV8
Ensembl - ENSGALG00000008609
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptk7aENSDARG00000011863Danio rerio
 PTK7ENSG00000112655Homo sapiens
 Ptk7ENSMUSG00000023972Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ROS1 / ROS proto-oncogene 1, receptor tyrosine kinase / P08922* / Q78DX7* / Proto-onco tyrosine-protein kinase ROS *ENSGALG0000001491323
INSRR / insulin receptor related receptor / P14616* / Q9WTL4* / Insulin receptor-related protein Insulin receptor-related protein alpha chain Insulin receptor-related protein beta chain*ENSGALG0000001325316
INSR / insulin receptor / P06213* / P15208* / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta*ENSGALG0000004075816
MUSK / muscle, skeletal receptor tyrosine protein kinase precursor / O15146* / Q61006* / muscle associated receptor tyrosine kinase* / Muscle, skeletal receptor tyrosine-protein kinase *ENSGALG0000001572815
NTRK3 / Q91044 / NT-3 growth factor receptor / Q16288* / Q6VNS1* / neurotrophic receptor tyrosine kinase 3*ENSGALG0000004024115
NTRK2 / Q91987 / BDNF/NT-3 growth factors receptor / P15209* / Q16620* / neurotrophic receptor tyrosine kinase 2*ENSGALG0000001259415
IGF1R / insulin-like growth factor 1 receptor precursor / P08069* / insulin like growth factor 1 receptor*ENSGALG0000004065115
LTK / leukocyte receptor tyrosine kinase / P08923* / P29376* / Leukocyte tyrosine kinase receptor *ENSGALG0000000861514
NTRK1 / high affinity nerve growth factor receptor precursor / P04629* / Q3UFB7* / neurotrophic receptor tyrosine kinase 1* / High affinity nerve growth factor receptor *ENSGALG0000001901914
DDR1 / Q03146* / Q08345* / discoidin domain receptor tyrosine kinase 1* / Epithelial discoidin domain-containing receptor 1 *ENSGALG0000000861613
ROR2 / receptor tyrosine kinase like orphan receptor 2 / Q01974* / Q9Z138*ENSGALG0000001520813
ROR1 / receptor tyrosine kinase like orphan receptor 1 / Q01973* / Q9Z139* / Inactive tyrosine-protein kinase transmembrane receptor ROR1 *ENSGALG0000001101913
DDR2 / discoidin domain receptor tyrosine kinase 2 / Q16832* / Q62371* / Discoidin domain-containing receptor 2 *ENSGALG0000003932213
ALK* / P97793* / Q9UM73* / ALK receptor tyrosine kinase* / ALK tyrosine kinase receptor *ENSGALG0000000903410


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR033592  Inactive tyrosine-protein kinase 7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001736 establishment of planar polarity IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0003281 ventricular septum development IEA
 biological_processGO:0003401 axis elongation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0045198 establishment of epithelial cell apical/basal polarity IEA
 biological_processGO:0060026 convergent extension IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060071 Wnt signaling pathway, planar cell polarity pathway IEA
 biological_processGO:0060484 lung-associated mesenchyme development IEA
 biological_processGO:0060976 coronary vasculature development IEA
 biological_processGO:0071300 cellular response to retinoic acid IEA
 biological_processGO:0090103 cochlea morphogenesis IEA
 biological_processGO:0090179 planar cell polarity pathway involved in neural tube closure IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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