ENSGALG00000008616


Gallus gallus

Features
Gene ID: ENSGALG00000008616
  
Biological name :DDR1
  
Synonyms : DDR1
  
Possible biological names infered from orthology : discoidin domain receptor tyrosine kinase 1 / Epithelial discoidin domain-containing receptor 1 / Q03146 / Q08345
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 2322632
Gene end: 2360426
  
Corresponding Affymetrix probe sets: Gga.18569.1.S1_at (Chicken Array)   Gga.18569.1.S1_s_at (Chicken Array)   Gga.7494.1.S1_at (Chicken Array)   GgaAffx.22651.1.S1_at (Chicken Array)   GgaAffx.22651.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056041
Ensembl peptide - ENSGALP00000014023
NCBI entrez gene - 417256     See in Manteia.
RefSeq - XM_015279514
RefSeq - NM_001012800
RefSeq - XM_015279512
RefSeq - XM_015279513
RefSeq Peptide - NP_001012818
swissprot - A0A1D5PT01
swissprot - Q5F3X2
Ensembl - ENSGALG00000008616
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddr2lENSDARG00000103830Danio rerio
 DDR1ENSG00000204580Homo sapiens
 Ddr1ENSMUSG00000003534Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDR2 / discoidin domain receptor tyrosine kinase 2 / Q16832* / Q62371* / Discoidin domain-containing receptor 2 *ENSGALG0000003932255
NTRK2 / Q91987 / BDNF/NT-3 growth factors receptor / P15209* / Q16620* / neurotrophic receptor tyrosine kinase 2*ENSGALG0000001259423
NTRK3 / Q91044 / NT-3 growth factor receptor / Q16288* / Q6VNS1* / neurotrophic receptor tyrosine kinase 3*ENSGALG0000004024123
NTRK1 / high affinity nerve growth factor receptor precursor / P04629* / Q3UFB7* / neurotrophic receptor tyrosine kinase 1* / High affinity nerve growth factor receptor *ENSGALG0000001901922
INSR / insulin receptor / P06213* / P15208* / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta*ENSGALG0000004075822
INSRR / insulin receptor related receptor / P14616* / Q9WTL4* / Insulin receptor-related protein Insulin receptor-related protein alpha chain Insulin receptor-related protein beta chain*ENSGALG0000001325321
IGF1R / insulin-like growth factor 1 receptor precursor / P08069* / insulin like growth factor 1 receptor*ENSGALG0000004065121
ROS1 / ROS proto-oncogene 1, receptor tyrosine kinase / P08922* / Q78DX7* / Proto-onco tyrosine-protein kinase ROS *ENSGALG0000001491321
MUSK / muscle, skeletal receptor tyrosine protein kinase precursor / O15146* / Q61006* / muscle associated receptor tyrosine kinase* / Muscle, skeletal receptor tyrosine-protein kinase *ENSGALG0000001572820
ROR1 / receptor tyrosine kinase like orphan receptor 1 / Q01973* / Q9Z139* / Inactive tyrosine-protein kinase transmembrane receptor ROR1 *ENSGALG0000001101917
ROR2 / receptor tyrosine kinase like orphan receptor 2 / Q01974* / Q9Z138*ENSGALG0000001520817
LTK / leukocyte receptor tyrosine kinase / P08923* / P29376* / Leukocyte tyrosine kinase receptor *ENSGALG0000000861516
PTK7 / inactive tyrosine-protein kinase 7 precursor / Q8BKG3* / Q13308* / Inactive tyrosine-protein kinase 7 * / protein tyrosine kinase 7 (inactive)*ENSGALG0000000860916
ALK* / P97793* / Q9UM73* / ALK receptor tyrosine kinase* / ALK tyrosine kinase receptor *ENSGALG0000000903412


Protein motifs (from Interpro)
Interpro ID Name
 IPR000421  Coagulation factor 5/8 C-terminal domain
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR002011  Tyrosine-protein kinase, receptor class II, conserved site
 IPR008266  Tyrosine-protein kinase, active site
 IPR008979  Galactose-binding-like domain superfamily
 IPR011009  Protein kinase-like domain superfamily
 IPR020635  Tyrosine-protein kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Non-integrin membrane-ECM interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008616 DDR1 / Q03146* / Q08345* / discoidin domain receptor tyrosine kinase 1* / Epithelial discoidin domain-containing receptor 1 *  / complex






 

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