ENSDARG00000020258


Danio rerio

Features
Gene ID: ENSDARG00000020258
  
Biological name :ewsr1a
  
Synonyms : ewsr1a / EWS RNA-binding protein 1a
  
Possible biological names infered from orthology : EWSR1 / EWS RNA binding protein 1 / Q01844 / Q61545 / RNA-binding protein EWS
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 7975585
Gene end: 7988417
  
Corresponding Affymetrix probe sets: Dr.5648.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000024102
Ensembl peptide - ENSDARP00000119576
NCBI entrez gene - 323597     See in Manteia.
RefSeq - NM_001115138
RefSeq Peptide - NP_001108610
swissprot - E9QEH8
swissprot - A0A0B4J1A5
ZFIN ID - ZDB-GENE-030131-2317
Ensembl - ENSDARG00000020258
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EWSR1ENSGALG00000008149Gallus gallus
 EWSR1ENSG00000182944Homo sapiens
 Ewsr1ENSMUSG00000009079Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ewsr1b / EWS RNA-binding protein 1b / EWSR1* / Q01844* / Q61545* / RNA-binding protein EWS * / EWS RNA binding protein 1*ENSDARG0000002046560
ewsr1b / EWS RNA-binding protein 1b / EWSR1* / Q01844* / EWS RNA binding protein 1*ENSDARG0000011701141
fus / FUS RNA binding protein / P35637* / P56959* / RNA-binding protein FUS *ENSDARG0000003796840
taf15 / TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor / Q92804* / TATA-box binding protein associated factor 15*ENSDARG0000007001934


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR001876  Zinc finger, RanBP2-type
 IPR033109  RNA-binding protein EWS
 IPR034869  EWS, RNA recognition motif
 IPR034870  TAF15/EWS/TLS family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007088 regulation of mitotic nuclear division IMP
 biological_processGO:0021954 central nervous system neuron development IMP
 biological_processGO:0051256 mitotic spindle midzone assembly IMP
 biological_processGO:1903041 regulation of chondrocyte hypertrophy IMP
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
brain apoptotic , abnormal
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary morphology , abnormal
Show

 ZFA:0000075 spinal cord spinal cord apoptotic , abnormal
spinal cord neuron disorganized , abnormal
Show

 ZFA:0000191 dentary dentary protruding , abnormal
Show

 ZFA:0000316 basihyal bone basihyal bone position , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage increased angle to palatoquadrate cartilage , abnormal
Meckels cartilage chondrocyte circular , abnormal
Meckels cartilage chondrocyte increased amount , abnormal
Meckels cartilage chondrocyte decreased size , abnormal
Meckels cartilage chondrocyte disorganized , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton morphology , abnormal
mandibular arch skeleton protruding , abnormal
Show

 ZFA:0009000 cell cell chromosome amount , abnormal
cell spindle structure , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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