ENSDARG00000020602


Danio rerio

Features
Gene ID: ENSDARG00000020602
  
Biological name :grk7a
  
Synonyms : G protein-coupled receptor kinase 7a / grk7a / Q49HM9
  
Possible biological names infered from orthology : G protein-coupled receptor kinase 7 / GRK7 / Q8WTQ7
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 16536453
Gene end: 16544343
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000091060
NCBI entrez gene - 566120     See in Manteia.
RefSeq - NM_001031841
RefSeq Peptide - NP_001027011
swissprot - Q49HM9
ZFIN ID - ZDB-GENE-050824-1
Ensembl - ENSDARG00000020602
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRK7ENSGALG00000002800Gallus gallus
 GRK7ENSG00000114124Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
grk7b / Q1XHL7 / G protein-coupled receptor kinase 7b / GRK7* / Q8WTQ7* / G protein-coupled receptor kinase 7*ENSDARG0000005553473
grk5l / G protein-coupled receptor kinase 5 like / GRK5* / P34947* / Q8VEB1* / G protein-coupled receptor kinase 5*ENSDARG0000007881545
grk4 / G protein-coupled receptor kinase 4 / O70291* / P32298*ENSDARG0000007044845
grk1a / G protein-coupled receptor kinase 1 a / GRK1* / Q15835* / G protein-coupled receptor kinase 1*ENSDARG0000005880344
grk6 / G protein-coupled receptor kinase 6 / P43250*ENSDARG0000003215744
grk1b / G protein-coupled receptor kinase 1 bENSDARG0000010468544
grk5 / G protein-coupled receptor kinase 5 / P34947* / Q8VEB1*ENSDARG0000003280140
grk3 / G protein-coupled receptor kinase 3 / P35626* / Q3UYH7* / Beta-adrenergic receptor kinase 2 *ENSDARG0000010409431


Protein motifs (from Interpro)
Interpro ID Name
 IPR000239  GPCR kinase
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016137  RGS domain
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0007603 phototransduction, visible light IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0050896 response to stimulus IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004703 G-protein coupled receptor kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0009881 photoreceptor activity IMP
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0050254 rhodopsin kinase activity IDA


Pathways (from Reactome)
Pathway description
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002193 rho / P35359 / rhodopsin / P08100*  / reaction
 ENSDARG00000070666 rhol / rhodopsin, like / RHO* / P15409* / P08100* / rhodopsin*  / reaction






 

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