ENSDARG00000055534


Danio rerio

Features
Gene ID: ENSDARG00000055534
  
Biological name :grk7b
  
Synonyms : G protein-coupled receptor kinase 7b / grk7b / Q1XHL7
  
Possible biological names infered from orthology : G protein-coupled receptor kinase 7 / GRK7 / Q8WTQ7
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 41740742
Gene end: 41754020
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000072364
NCBI entrez gene - 373871     See in Manteia.
RefSeq - NM_001033090
RefSeq Peptide - NP_001028262
swissprot - Q1XHL7
ZFIN ID - ZDB-GENE-030904-3
Ensembl - ENSDARG00000055534
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRK7ENSGALG00000002800Gallus gallus
 GRK7ENSG00000114124Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
grk7a / Q49HM9 / G protein-coupled receptor kinase 7a / GRK7* / Q8WTQ7* / G protein-coupled receptor kinase 7*ENSDARG0000002060274
grk5l / G protein-coupled receptor kinase 5 like / GRK5* / P34947* / Q8VEB1* / G protein-coupled receptor kinase 5*ENSDARG0000007881544
grk1b / G protein-coupled receptor kinase 1 bENSDARG0000010468543
grk4 / G protein-coupled receptor kinase 4 / O70291* / P32298*ENSDARG0000007044843
grk1a / G protein-coupled receptor kinase 1 a / GRK1* / Q15835* / G protein-coupled receptor kinase 1*ENSDARG0000005880342
grk6 / G protein-coupled receptor kinase 6 / P43250*ENSDARG0000003215742
grk5 / G protein-coupled receptor kinase 5 / P34947* / Q8VEB1*ENSDARG0000003280139
grk3 / G protein-coupled receptor kinase 3 / P35626* / Q3UYH7* / Beta-adrenergic receptor kinase 2 *ENSDARG0000010409432


Protein motifs (from Interpro)
Interpro ID Name
 IPR000239  GPCR kinase
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016137  RGS domain
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0050896 response to stimulus IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004703 G-protein coupled receptor kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0050254 rhodopsin kinase activity IDA


Pathways (from Reactome)
Pathway description
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000070666 rhol / rhodopsin, like / RHO* / P15409* / P08100* / rhodopsin*  / reaction
 ENSDARG00000002193 rho / P35359 / rhodopsin / P08100*  / reaction






 

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contact: otassy@igbmc.fr