ENSDARG00000020785


Danio rerio

Features
Gene ID: ENSDARG00000020785
  
Biological name :lama4
  
Synonyms : lama4 / laminin, alpha 4
  
Possible biological names infered from orthology : laminin subunit alpha 4 / P97927 / Q16363
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 218886
Gene end: 259965
  
Corresponding Affymetrix probe sets: Dr.19727.1.A1_at (Zebrafish Array)   Dr.19760.1.A1_at (Zebrafish Array)   NM_001039065_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000006065
NCBI entrez gene - 566796     See in Manteia.
RefSeq - NM_001039065
RefSeq Peptide - NP_001034154
swissprot - F1QYU0
ZFIN ID - ZDB-GENE-040724-213
Ensembl - ENSDARG00000020785
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000015001Gallus gallus
 LAMA4ENSG00000112769Homo sapiens
 Lama4ENSMUSG00000019846Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lama5 / laminin, alpha 5 / O15230* / Q61001* / laminin subunit alpha 5*ENSDARG0000005854327
lama3 / laminin, alpha 3 / Q16787* / Q61789* / laminin subunit alpha 3* / Mus musculus laminin, alpha 3 (Lama3), transcript variant 2, mRNA.*ENSDARG0000007146220
lama1 / laminin, alpha 1 / P25391* / laminin subunit alpha 1*ENSDARG0000010227720
si:ch211-241e1.3 / LAMA3* / Q16787* / Q61789* / laminin subunit alpha 3* / Mus musculus laminin, alpha 3 (Lama3), transcript variant 2, mRNA.*ENSDARG0000002261517
lamb1a / laminin, beta 1a / LAMB1* / P02469* / P07942* / laminin subunit beta 1*ENSDARG0000010120910
CABZ01092781.1 / LAMB3* / Q13751* / laminin subunit beta 3*ENSDARG0000011004010
lamb2 / laminin, beta 2 (laminin S) / P55268* / Q61292* / laminin subunit beta 2*ENSDARG0000000208410
lamb1b / laminin, beta 1b / LAMB1* / P02469* / P07942* / laminin subunit beta 1*ENSDARG0000004552410
lamb2l / laminin, beta 2-likeENSDARG000000339509
lamb4 / laminin, beta 4 / A4D0S4* / laminin subunit beta 4*ENSDARG000000391339
lamc1 / Q1LVF0 / laminin, gamma 1 / P11047* / laminin subunit gamma 1*ENSDARG000000362799
lamc3 / laminin, gamma 3 / Q9R0B6* / Q9Y6N6* / laminin subunit gamma 3*ENSDARG000000935727
lamc2 / laminin, gamma 2 / Q13753* / laminin subunit gamma 2*ENSDARG000000682885
si:dkey-202e22.2ENSDARG000000612604
lama2 / laminin, alpha 2 / P24043* / laminin subunit alpha 2*ENSDARG000000993904
ntn4 / netrin 4 / Q9HB63* / Q9JI33*ENSDARG000001020663
CABZ01065423.1 / LAMA2* / P24043* / laminin subunit alpha 2*ENSDARG000001120192


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR002049  Laminin EGF domain
 IPR009254  Laminin alpha, domain I
 IPR010307  Laminin domain II
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001885 endothelial cell development IGI
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0016203 muscle attachment IMP
 biological_processGO:0030155 regulation of cell adhesion IEA
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0030903 notochord development IGI
 biological_processGO:0045995 regulation of embryonic development IEA
 biological_processGO:0048514 blood vessel morphogenesis IGI
 molecular_functionGO:0005102 signaling receptor binding IEA


Pathways (from Reactome)
Pathway description
Laminin interactions
MET activates PTK2 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000099 brain vasculature brain vasculature broken , abnormal
Show

 ZFA:0000114 heart heart decreased functionality , abnormal
Show

 ZFA:0000155 somite somite morphology , abnormal
somite U-shaped , abnormal
Show

 ZFA:0001056 myotome myotome morphology , abnormal
Show

 ZFA:0001079 blood vasculature blood vasculature broken , abnormal
Show

 ZFA:0001462 somite border somite border shape , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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