ENSDARG00000099390


Danio rerio

Features
Gene ID: ENSDARG00000099390
  
Biological name :lama2
  
Synonyms : lama2 / laminin, alpha 2
  
Possible biological names infered from orthology : laminin subunit alpha 2 / P24043 / Q60675
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 1903481
Gene end: 1979652
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000131993
swissprot - A0A0G2KI51
ZFIN ID - ZDB-GENE-060119-1
Ensembl - ENSDARG00000099390
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LAMA2ENSGALG00000042388Gallus gallus
 LAMA2ENSG00000196569Homo sapiens
 Lama2ENSMUSG00000019899Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lama1 / laminin, alpha 1 / P25391* / laminin subunit alpha 1*ENSDARG0000010227747
lama5 / laminin, alpha 5 / O15230* / Q61001* / laminin subunit alpha 5*ENSDARG0000005854331
lamb2l / laminin, beta 2-likeENSDARG0000003395020
lamb2 / laminin, beta 2 (laminin S) / P55268* / Q61292* / laminin subunit beta 2*ENSDARG0000000208419
lamb1a / laminin, beta 1a / LAMB1* / P02469* / P07942* / laminin subunit beta 1*ENSDARG0000010120919
lamb1b / laminin, beta 1b / LAMB1* / P02469* / P07942* / laminin subunit beta 1*ENSDARG0000004552419
lamc1 / Q1LVF0 / laminin, gamma 1 / P11047* / laminin subunit gamma 1*ENSDARG0000003627919
lamc3 / laminin, gamma 3 / Q9R0B6* / Q9Y6N6* / laminin subunit gamma 3*ENSDARG0000009357218
lamb4 / laminin, beta 4 / A4D0S4* / laminin subunit beta 4*ENSDARG0000003913317
lama4 / laminin, alpha 4 / P97927* / Q16363* / laminin subunit alpha 4*ENSDARG000000207859
lama3 / laminin, alpha 3 / Q16787* / Q61789* / laminin subunit alpha 3* / Mus musculus laminin, alpha 3 (Lama3), transcript variant 2, mRNA.*ENSDARG000000714628
si:ch211-241e1.3 / LAMA3* / Q16787* / Q61789* / laminin subunit alpha 3* / Mus musculus laminin, alpha 3 (Lama3), transcript variant 2, mRNA.*ENSDARG000000226157
si:dkey-202e22.2ENSDARG000000612603
ntn4 / netrin 4 / Q9HB63* / Q9JI33*ENSDARG000001020663
lamc2 / laminin, gamma 2 / Q13753* / laminin subunit gamma 2*ENSDARG000000682883
CABZ01065423.1 / LAMA2* / P24043* / laminin subunit alpha 2*ENSDARG000001120191
CABZ01092781.1 / LAMB3* / Q13751* / laminin subunit beta 3*ENSDARG000001100400


Protein motifs (from Interpro)
Interpro ID Name
 IPR000034  Laminin IV
 IPR000742  EGF-like domain
 IPR002049  Laminin EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007517 muscle organ development IMP
 biological_processGO:0016203 muscle attachment IMP
 biological_processGO:0022011 myelination in peripheral nervous system IGI
 biological_processGO:0060538 skeletal muscle organ development IMP


Pathways (from Reactome)
Pathway description
Laminin interactions
MET activates PTK2 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
brain decreased size , abnormal
Show

 ZFA:0000012 central nervous system central nervous system morphology , abnormal
Show

 ZFA:0000107 eye eye morphology , abnormal
eye decreased size , abnormal
Show

 ZFA:0000135 notochord notochord morphology , abnormal
Show

 ZFA:0000155 somite somite muscle cell detached from somite , abnormal
somite quality , abnormal
somite disorganized , abnormal
somite U-shaped , abnormal
somite degenerate , abnormal
Show

 ZFA:0000473 trunk musculature trunk musculature degenerate , abnormal
trunk musculature quality , abnormal
Show

 ZFA:0000610 vertical myoseptum vertical myoseptum deformed , abnormal
Show

 ZFA:0000944 posterior lateral line posterior lateral line Schwann cell development decreased process quality , abnormal
posterior lateral line myelination of posterior lateral line nerve axons arrested , abnormal
posterior lateral line myelination of posterior lateral line nerve axons decreased occurrence , abnormal
Show

 ZFA:0001056 myotome myotome structure , abnormal
myotome extracellular matrix structure , abnormal
myotome skeletal muscle cell decreased amount , abnormal
myotome skeletal muscle cell degeneration , abnormal
myotome refractivity , abnormal
myotome morphology , abnormal
myotome degenerate , abnormal
myotome skeletal muscle degenerate , abnormal
myotome decreased size , abnormal
myotome dystrophic , abnormal
Show

 ZFA:0001089 myoseptum myoseptum broken , abnormal
Show

 ZFA:0001094 whole organism whole organism immobile , abnormal
whole organism viability , abnormal
whole organism decreased speed , abnormal
whole organism decreased size , abnormal
Show

 ZFA:0005145 muscle muscle damaged , abnormal
muscle dystrophic , abnormal
muscle refractivity , abnormal
muscle degenerate , abnormal
muscle disorganized , abnormal
Show

 ZFA:0005277 skeletal muscle skeletal muscle structure , abnormal
skeletal muscle structure , ameliorated
skeletal muscle disorganized , abnormal
skeletal muscle disorganized , ameliorated
skeletal muscle deformed , abnormal
skeletal muscle decreased strength , abnormal
skeletal muscle morphology , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell detached from vertical myoseptum , abnormal
skeletal muscle cell retracted , abnormal
skeletal muscle cell dystrophic , abnormal
skeletal muscle cell apoptotic , abnormal
skeletal muscle cell detached from myoseptum , abnormal
skeletal muscle cell disorganized , abnormal
skeletal muscle cell undulate , abnormal
skeletal muscle cell alignment skeletal muscle , abnormal
skeletal muscle cell filamentous actin aggregated , abnormal
skeletal muscle cell myofibril detached from myotome muscle tendon junction, abnormal
skeletal muscle cell myofibril detached from skeletal muscle cell myofibril, abnormal
skeletal muscle cell Z disc disorganized , abnormal
skeletal muscle cell M band disorganized , abnormal
Show

 ZFA:0009116 slow muscle cell slow muscle cell detached from myoseptum , abnormal
Show

 ZFA:0009117 fast muscle cell fast muscle cell detached from myoseptum , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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