ENSDARG00000021916


Danio rerio

Features
Gene ID: ENSDARG00000021916
  
Biological name :vax1
  
Synonyms : vax1 / ventral anterior homeobox 1
  
Possible biological names infered from orthology : Q2NKI2 / Q5SQQ9
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 21432693
Gene end: 21441464
  
Corresponding Affymetrix probe sets: DrAffx.1.61.S1_at (Zebrafish Array)   NM_194410_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000039283
NCBI entrez gene - 373870     See in Manteia.
RefSeq - NM_194410
RefSeq Peptide - NP_919391
swissprot - A0A0R4I9B5
ZFIN ID - ZDB-GENE-030904-9
Ensembl - ENSDARG00000021916
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 VAX1ENSGALG00000009261Gallus gallus
 VAX1ENSG00000148704Homo sapiens
 Vax1ENSMUSG00000006270Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
vax2 / Q801E1 / ventral anterior homeobox 2 / Q9UIW0* / Q9WTP9*ENSDARG0000005870246
noto / notochord homeobox / A8MTQ0* / Q5TIS6* / Homeobox protein notochord *ENSDARG0000002120118
emx3 / empty spiracles homeobox 3ENSDARG0000002041716
en1b / engrailed homeobox 1b / EN1* / P09065* / Q05925* / engrailed homeobox 1* / Homeobox protein engrailed-1 *ENSDARG0000009873015
en1a / engrailed homeobox 1a / EN1* / Q05925* / engrailed homeobox 1*ENSDARG0000001432115
emx1 / Q804S6 / empty spiracles homeobox 1ENSDARG0000003956915
en2a / P09015 / engrailed homeobox 2a / EN2* / P09066* / P19622* / engrailed homeobox 2* / Homeobox protein engrailed-2 *ENSDARG0000002659915
en2b / engrailed homeobox 2b / EN2* / P09066* / P19622* / engrailed homeobox 2* / Homeobox protein engrailed-2 *ENSDARG0000003886815
emx2 / empty spiracles homeobox 2 / Q04743* / Q04744* / Homeobox protein EMX2 *ENSDARG0000003970114


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR033020  Ventral anterior homeobox 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0007420 brain development IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000109 forebrain forebrain retinal pigmented epithelium mislocalized adaxially , abnormal
Show

 ZFA:0000152 retina retina perforate , abnormal
retina intrinsic apoptotic signaling pathway by p53 class mediator increased occurrence , abnormal
retina cell apoptotic , abnormal
Show

 ZFA:0001284 optic fissure optic fissure open , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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