ENSDARG00000058702


Danio rerio

Features
Gene ID: ENSDARG00000058702
  
Biological name :vax2
  
Synonyms : Q801E1 / vax2 / ventral anterior homeobox 2
  
Possible biological names infered from orthology : Q9UIW0 / Q9WTP9
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 8844285
Gene end: 8881514
  
Corresponding Affymetrix probe sets: DrAffx.1.62.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000076061
NCBI entrez gene - 373869     See in Manteia.
swissprot - B3DIR5
swissprot - Q801E1
ZFIN ID - ZDB-GENE-030904-8
Ensembl - ENSDARG00000058702
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 VAX2ENSG00000116035Homo sapiens
 Vax2ENSMUSG00000034777Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
vax1 / ventral anterior homeobox 1 / Q2NKI2* / Q5SQQ9*ENSDARG0000002191647
en1b / engrailed homeobox 1b / EN1* / P09065* / Q05925* / engrailed homeobox 1* / Homeobox protein engrailed-1 *ENSDARG0000009873017
noto / notochord homeobox / A8MTQ0* / Q5TIS6* / Homeobox protein notochord *ENSDARG0000002120117
emx1 / Q804S6 / empty spiracles homeobox 1ENSDARG0000003956917
emx2 / empty spiracles homeobox 2 / Q04743* / Q04744* / Homeobox protein EMX2 *ENSDARG0000003970116
emx3 / empty spiracles homeobox 3ENSDARG0000002041716
en1a / engrailed homeobox 1a / EN1* / Q05925* / engrailed homeobox 1*ENSDARG0000001432116
en2b / engrailed homeobox 2b / EN2* / P09066* / P19622* / engrailed homeobox 2* / Homeobox protein engrailed-2 *ENSDARG0000003886816
en2a / P09015 / engrailed homeobox 2a / EN2* / P09066* / P19622* / engrailed homeobox 2* / Homeobox protein engrailed-2 *ENSDARG0000002659915


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR033021  Ventral anterior homeobox 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0021554 optic nerve development IMP
 biological_processGO:0030900 forebrain development ISS
 biological_processGO:0048048 embryonic eye morphogenesis IEA
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0060042 retina morphogenesis in camera-type eye IGI
 biological_processGO:0061386 closure of optic fissure IMP
 biological_processGO:0090259 regulation of retinal ganglion cell axon guidance IMP
 biological_processGO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator IGI
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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