ENSDARG00000039701


Danio rerio

Features
Gene ID: ENSDARG00000039701
  
Biological name :emx2
  
Synonyms : empty spiracles homeobox 2 / emx2
  
Possible biological names infered from orthology : Homeobox protein EMX2 / Q04743 / Q04744
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 19322686
Gene end: 19327657
  
Corresponding Affymetrix probe sets: Dr.278.1.S1_at (Zebrafish Array)   Dr.9996.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000058035
swissprot - Q90264
ZFIN ID - ZDB-GENE-990415-54
Ensembl - ENSDARG00000039701
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EMX2ENSGALG00000009302Gallus gallus
 EMX2ENSG00000170370Homo sapiens
 Emx2ENSMUSG00000043969Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
emx1 / Q804S6 / empty spiracles homeobox 1ENSDARG0000003956962
emx3 / empty spiracles homeobox 3ENSDARG0000002041758
noto / notochord homeobox / A8MTQ0* / Q5TIS6* / Homeobox protein notochord *ENSDARG0000002120120
vax2 / Q801E1 / ventral anterior homeobox 2 / Q9UIW0* / Q9WTP9*ENSDARG0000005870220
en2a / P09015 / engrailed homeobox 2a / EN2* / P09066* / P19622* / engrailed homeobox 2* / Homeobox protein engrailed-2 *ENSDARG0000002659919
vax1 / ventral anterior homeobox 1 / Q2NKI2* / Q5SQQ9*ENSDARG0000002191618
en1b / engrailed homeobox 1b / EN1* / P09065* / Q05925* / engrailed homeobox 1* / Homeobox protein engrailed-1 *ENSDARG0000009873018
en2b / engrailed homeobox 2b / EN2* / P09066* / P19622* / engrailed homeobox 2* / Homeobox protein engrailed-2 *ENSDARG0000003886818
en1a / engrailed homeobox 1a / EN1* / Q05925* / engrailed homeobox 1*ENSDARG0000001432116


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007420 brain development IEP
 biological_processGO:0060121 vestibular receptor cell stereocilium organization IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000030 macula utricle macula utricle stereocilium bundle orientation macula utricle , abnormal
macula utricle vestibular receptor cell stereocilium organization decreased process quality , abnormal
Show

 ZFA:0000166 lateral crista lateral crista stereocilium bundle orientation lateral crista , abnormal
lateral crista vestibular receptor cell stereocilium organization decreased process quality , abnormal
Show

 ZFA:0000243 neuromast neuromast stereocilium bundle bilateral symmetry , abnormal
neuromast stereocilium bundle unidirectional , abnormal
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 ZFA:0000505 dorsal telencephalon dorsal telencephalon morphology , abnormal
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 ZFA:0000940 posterior lateral line neuromast posterior lateral line neuromast neuromast hair cell absent , abnormal
Show

 ZFA:0000944 posterior lateral line posterior lateral line neuromast hair cell development decreased process quality , abnormal
posterior lateral line posterior lateral line neuromast development decreased process quality , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell stereocilium bundle orientation neuromast , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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