ENSDARG00000026582


Danio rerio

Features
Gene ID: ENSDARG00000026582
  
Biological name :iscub
  
Synonyms : iron-sulfur cluster assembly enzyme b / iscub
  
Possible biological names infered from orthology : iron-sulfur cluster assembly enzyme / Iron-sulfur cluster assembly enzyme ISCU, mitochondrial / ISCU / Q9D7P6 / Q9H1K1
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 31860043
Gene end: 31868847
  
Corresponding Affymetrix probe sets: Dr.1482.1.A1_at (Zebrafish Array)   NM_001017800_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000033254
Ensembl peptide - ENSDARP00000120406
Ensembl peptide - ENSDARP00000124124
NCBI entrez gene - 550498     See in Manteia.
RefSeq - NM_001017800
RefSeq Peptide - NP_001017800
swissprot - F1QM53
swissprot - E9QGB4
swissprot - F8W4V5
ZFIN ID - ZDB-GENE-050417-332
Ensembl - ENSDARG00000026582
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ISCUENSGALG00000004869Gallus gallus
 ISCUENSG00000136003Homo sapiens
 IscuENSMUSG00000025825Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ISCU (1 of many) / si:ch211-191d15.2 / ISCU* / Q9D7P6* / Q9H1K1* / iron-sulfur cluster assembly enzyme* / Iron-sulfur cluster assembly enzyme ISCU, mitochondrial *ENSDARG0000003559673


Protein motifs (from Interpro)
Interpro ID Name
 IPR002871  NIF system FeS cluster assembly, NifU, N-terminal
 IPR011339  ISC system FeS cluster assembly, IscU scaffold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006879 cellular iron ion homeostasis IBA
 biological_processGO:0016226 iron-sulfur cluster assembly IEA
 biological_processGO:0097428 protein maturation by iron-sulfur cluster transfer IBA
 cellular_componentGO:0005759 mitochondrial matrix IBA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008198 ferrous iron binding IBA
 molecular_functionGO:0036455 iron-sulfur transferase activity IBA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IBA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IBA


Pathways (from Reactome)
Pathway description
Mitochondrial iron-sulfur cluster biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000078352 lyrm4 / B8JLQ0 / LYR motif containing 4 / Q8K215* / Q9HD34* / LYR motif-containing protein 4 *  / complex
 ENSDARG00000026582 iscub / iron-sulfur cluster assembly enzyme b / ISCU* / Q9D7P6* / Q9H1K1* / iron-sulfur cluster assembly enzyme* / Iron-sulfur cluster assembly enzyme ISCU, mitochondrial *  / complex
 ENSDARG00000101110 LYRM4 / si:ch211-152c8.4 / Q8K215* / Q9HD34* / LYR motif containing 4* / LYR motif-containing protein 4 *  / complex
 ENSDARG00000062237 nfs1 / NFS1 cysteine desulfurase / Q9Y697* / Q9Z1J3* / AL109827.1* / Cysteine desulfurase, mitochondrial *  / complex






 

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