ENSDARG00000062237


Danio rerio

Features
Gene ID: ENSDARG00000062237
  
Biological name :nfs1
  
Synonyms : nfs1 / NFS1 cysteine desulfurase
  
Possible biological names infered from orthology : AL109827.1 / Cysteine desulfurase, mitochondrial / Q9Y697 / Q9Z1J3
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 24348425
Gene end: 24356093
  
Corresponding Affymetrix probe sets: Dr.26514.1.A1_at (Zebrafish Array)   NM_001044993_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000084180
NCBI entrez gene - 562714     See in Manteia.
RefSeq - NM_001044993
RefSeq Peptide - NP_001038458
swissprot - Q1LYQ9
ZFIN ID - ZDB-GENE-060405-1
Ensembl - ENSDARG00000062237
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NFS1ENSGALG00000001568Gallus gallus
 AL109827.1ENSG00000272897Homo sapiens
 NFS1ENSG00000244005Homo sapiens
 Nfs1ENSMUSG00000027618Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
scly / selenocysteine lyase / Q96I15*ENSDARG0000007381329


Protein motifs (from Interpro)
Interpro ID Name
 IPR000192  Aminotransferase class V domain
 IPR010240  Cysteine desulfurase IscS
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR016454  Cysteine desulfurase
 IPR020578  Aminotransferase class-V, pyridoxal-phosphate binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0044571 [2Fe-2S] cluster assembly IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0031071 cysteine desulfurase activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial iron-sulfur cluster biogenesis
Molybdenum cofactor biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000026582 iscub / iron-sulfur cluster assembly enzyme b / ISCU* / Q9D7P6* / Q9H1K1* / iron-sulfur cluster assembly enzyme* / Iron-sulfur cluster assembly enzyme ISCU, mitochondrial *  / complex
 ENSDARG00000008239 mocs3 / molybdenum cofactor synthesis 3 / A2BDX3* / O95396* / Adenylyltransferase and sulfurtransferase MOCS3 Molybdopterin-synthase adenylyltransferase Molybdopterin-synthase sulfurtransferase*  / reaction
 ENSDARG00000062237 nfs1 / NFS1 cysteine desulfurase / Q9Y697* / Q9Z1J3* / AL109827.1* / Cysteine desulfurase, mitochondrial *  / complex
 ENSDARG00000078352 lyrm4 / B8JLQ0 / LYR motif containing 4 / Q8K215* / Q9HD34* / LYR motif-containing protein 4 *  / complex
 ENSDARG00000101110 LYRM4 / si:ch211-152c8.4 / Q8K215* / Q9HD34* / LYR motif containing 4* / LYR motif-containing protein 4 *  / complex






 

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