ENSDARG00000034344


Danio rerio

Features
Gene ID: ENSDARG00000034344
  
Biological name :pcdh19
  
Synonyms : pcdh19 / protocadherin 19
  
Possible biological names infered from orthology : Q80TF3 / Q8TAB3
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 40300961
Gene end: 40390757
  
Corresponding Affymetrix probe sets: Dr.16091.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000142262
Ensembl peptide - ENSDARP00000124001
Ensembl peptide - ENSDARP00000155634
NCBI entrez gene - 555688     See in Manteia.
RefSeq - NM_001127519
RefSeq - XM_009291120
RefSeq Peptide - NP_001120991
swissprot - F8W3X3
swissprot - A0A140LG84
ZFIN ID - ZDB-GENE-030131-4218
Ensembl - ENSDARG00000034344
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PCDH19ENSGALG00000006822Gallus gallus
 PCDH19ENSG00000165194Homo sapiens
 Pcdh19ENSMUSG00000051323Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pcdh17 / protocadherin 17 / O14917*ENSDARG0000002704146
pcdh18a / protocadherin 18a / PCDH18* / Q9HCL0* / protocadherin 18*ENSDARG0000008980536
pcdh18b / protocadherin 18b / Q9HCL0* / PCDH18* / Q8VHR0* / protocadherin 18*ENSDARG0000005249436
pcdh10a / protocadherin 10a / PCDH10* / Q9P2E7* / protocadherin 10*ENSDARG0000009972934
si:ch73-233f7.1ENSDARG0000006190929
pcdh12 / protocadherin 12 / O55134* / Q9NPG4*ENSDARG0000007659428
PCDH8 / si:ch211-199f5.1 / O95206* / Q7TSK3* / protocadherin 8*ENSDARG0000010218528
pcdh2ab5 / protocadherin 2 alpha b 5 / Pcdha3* / Pcdha2* / protocadherin alpha 2* / protocadherin alpha 3*ENSDARG0000009034827
pcdh1a6 / pcdh1a4 / protocadherin 1 alpha 6 / Pcdha3* / Pcdha2* / protocadherin alpha 2* / protocadherin alpha 3*ENSDARG0000009717026
pcdh1gb9 / protocadherin 1 gamma b 9 / Q9Y5E8* / Q91XY4* / Pcdhga3* / Pcdhga4* / Pcdhga5* / Pcdhga6* / Pcdhga7* / Pcdhga8* / PCDHB15* / Pcdhga10* / Pcdhga11* / protocadherin beta 15* / Prot...ENSDARG0000008847526
pcdh8 / protocadherin 8 / O95206*ENSDARG0000000646726
pcdh1g30 / protocadherin 1 gamma 30ENSDARG0000010186526
pcdh2g5 / pcdh2g17 / pcdh2g20 / pcdh2g28 / pcdh2g29 / pcdh2g13 / protocadherin 2 gamma 5 / Q9Y5E8* / PCDHB15* / protocadherin beta 15*ENSDARG0000009878825
pcdh1g2 / protocadherin 1 gamma 2 / Q9Y5E8* / Q91XY4* / Pcdhga3* / Pcdhga4* / Pcdhga5* / Pcdhga6* / Pcdhga7* / Pcdhga8* / PCDHB15* / Pcdhga10* / Pcdhga11* / protocadherin beta 15* / Protoca...ENSDARG0000010123225
pcdh1g31 / protocadherin 1 gamma 31ENSDARG0000010067025
pcdh2ab11 / protocadherin 2 alpha b 11 / Pcdha3* / Pcdha2* / protocadherin alpha 2* / protocadherin alpha 3*ENSDARG0000008959325
pcdh1gb2 / protocadherin 1 gamma b 2 / Q9Y5E8* / Q91XY4* / Pcdhga3* / Pcdhga4* / Pcdhga5* / Pcdhga6* / Pcdhga7* / Pcdhga8* / PCDHB15* / Pcdhga10* / Pcdhga11* / protocadherin beta 15* / Prot...ENSDARG0000010130724
PCDHB15 / protocadherin beta 15 / Q9Y5E8*ENSDARG0000010133824


Protein motifs (from Interpro)
Interpro ID Name
 IPR002126  Cadherin
 IPR013164  Cadherin, N-terminal
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR030716  Protocadherin-19


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001841 neural tube formation IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0048854 brain morphogenesis IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain disorganized , abnormal
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 ZFA:0000029 hindbrain hindbrain disorganized , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary morphology , abnormal
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 ZFA:0000050 optic vesicle optic vesicle malformed , abnormal
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 ZFA:0000109 forebrain forebrain condensed , abnormal
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 ZFA:0000131 neural keel neural keel increased width , abnormal
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 ZFA:0000133 neural rod neural rod increased width , abnormal
neural rod disorganized , abnormal
neural rod Y-shaped , abnormal
neural rod collapsed , abnormal
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 ZFA:0000445 optic tectum optic tectum has extra parts of type neuron , abnormal
optic tectum cell proliferation increased occurrence , abnormal
optic tectum neuron morphology , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001261 ventricular system ventricular system epithelium morphology , abnormal
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 ZFA:0001321 neurocranial trabecula neurocranial trabecula fused with neurocranial trabecula , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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