ENSDARG00000035127


Danio rerio

Features
Gene ID: ENSDARG00000035127
  
Biological name :rxrab
  
Synonyms : retinoid x receptor, alpha b / rxrab
  
Possible biological names infered from orthology : P19793 / P28700 / retinoid X receptor alpha / RXRA
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 64476118
Gene end: 64511428
  
Corresponding Affymetrix probe sets: Dr.624.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000004918
swissprot - F1RDN3
ZFIN ID - ZDB-GENE-990415-243
Ensembl - ENSDARG00000035127
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RXRAENSGALG00000042055Gallus gallus
 RXRAENSG00000186350Homo sapiens
 RxraENSMUSG00000015846Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rxraa / retinoid X receptor, alpha a / RXRA* / P19793* / P28700* / retinoid X receptor alpha*ENSDARG0000005773791
rxrgb / Q6DHP9 / retinoid X receptor, gamma b / RXRG* / P28705* / P48443* / retinoid X receptor gamma* / Retinoic acid receptor RXR-gamma *ENSDARG0000000469780
rxrba / Q7SYN5 / retinoid x receptor, beta a / RXRB* / P28704* / P28702* / retinoid X receptor beta*ENSDARG0000007895480
rxrbb / retinoid x receptor, beta b / RXRB* / P28702* / P28704* / retinoid X receptor beta*ENSDARG0000000200674
nr2f2 / nuclear receptor subfamily 2, group F, member 2 / P24468* / P43135*ENSDARG0000004092639
nr2f5 / Q06726 / nuclear receptor subfamily 2, group F, member 5ENSDARG0000003317239
hnf4a / hepatocyte nuclear factor 4, alpha / P41235* / P49698*ENSDARG0000002149439
Q06725 / nr2f1a / nuclear receptor subfamily 2, group F, member 1a / NR2F1* / P10589* / nuclear receptor subfamily 2 group F member 1*ENSDARG0000005269538
nr2f6a / nuclear receptor subfamily 2, group F, member 6a / NR2F6* / P43136* / P10588* / nuclear receptor subfamily 2 group F member 6*ENSDARG0000000360737
hnf4g / hepatocyte nuclear factor 4, gamma / Q14541*ENSDARG0000007156537
nr2f1b / Q6PH18 / nuclear receptor subfamily 2, group F, member 1bENSDARG0000001716837
nr2f6b / nuclear receptor subfamily 2, group F, member 6b / NR2F6* / P43136* / P10588* / nuclear receptor subfamily 2 group F member 6*ENSDARG0000000316536
nr2c2 / nuclear receptor subfamily 2, group C, member 2 / P49116* / P49117*ENSDARG0000004247736
nr2c1 / nuclear receptor subfamily 2, group C, member 1 / P13056* / Q505F1*ENSDARG0000004552732
nr2e3 / nuclear receptor subfamily 2, group E, member 3 / Q9QXZ7* / Q9Y5X4* / Photoreceptor-specific nuclear receptor *ENSDARG0000004590432
nr2e1 / nuclear receptor subfamily 2, group E, member 1 / Q64104* / Q9Y466*ENSDARG0000001710732
CABZ01057488.1ENSDARG0000010474227


Protein motifs (from Interpro)
Interpro ID Name
 IPR000003  Retinoid X receptor/HNF4
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR021780  Nuclear/hormone receptor activator site AF-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Recycling of bile acids and salts
Synthesis of bile acids and bile salts
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Import of palmitoyl-CoA into the mitochondrial matrix
Regulation of pyruvate dehydrogenase (PDH) complex
Endogenous sterols
Nuclear Receptor transcription pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
SUMOylation of intracellular receptors
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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