ENSGALG00000042055


Gallus gallus

Features
Gene ID: ENSGALG00000042055
  
Biological name :RXRA
  
Synonyms : retinoid X receptor alpha / RXRA
  
Possible biological names infered from orthology : P19793 / P28700
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 7753256
Gene end: 7827661
  
Corresponding Affymetrix probe sets: GgaAffx.1720.1.S1_at (Chicken Array)   GgaAffx.1720.1.S1_s_at (Chicken Array)   GgaAffx.1720.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046810
NCBI entrez gene - 417143     See in Manteia.
RefSeq - XM_003642291
RefSeq - XM_004945961
RefSeq - XM_015279790
swissprot - A0A1D5P2B5
Ensembl - ENSGALG00000042055
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rxraaENSDARG00000057737Danio rerio
 rxrabENSDARG00000035127Danio rerio
 RXRAENSG00000186350Homo sapiens
 RxraENSMUSG00000015846Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RXRG / retinoic acid receptor RXR-gamma / P28705* / P48443* / retinoid X receptor gamma*ENSGALG0000004073058
NR2C2 / nuclear receptor subfamily 2 group C member 2 / P49116* / P49117*ENSGALG0000000851929
NR2F1 / nuclear receptor subfamily 2 group F member 1 / P10589*ENSGALG0000002790728
NR2F2 / COUP transcription factor 2 / P24468* / P43135* / nuclear receptor subfamily 2 group F member 2*ENSGALG0000000700028
HNF4G / hepatocyte nuclear factor 4 gamma / Q14541*ENSGALG0000004262125
NR2F6 / nuclear receptor subfamily 2 group F member 6 / P10588* / P43136*ENSGALG0000004301024
NR2C1 / nuclear receptor subfamily 2 group C member 1 / P13056* / Q505F1*ENSGALG0000001132723
HNF4A / hepatocyte nuclear factor 4-alpha / P41235* / P49698*ENSGALG0000000428523
HNF4beta / hepatic nuclear factor 4beta ENSGALG0000000570822
NR2E3 / photoreceptor-specific nuclear receptor / Q9QXZ7* / Q9Y5X4* / nuclear receptor subfamily 2 group E member 3*ENSGALG0000000209321
NR2E1 / nuclear receptor subfamily 2 group E member 1 / Q64104* / Q9Y466*ENSGALG0000001530521


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR013088  Zinc finger, NHR/GATA-type
 IPR021780  Nuclear/hormone receptor activator site AF-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001890 placenta development IEA
 biological_processGO:0001893 maternal placenta development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007566 embryo implantation IEA
 biological_processGO:0019048 modulation by virus of host morphology or physiology IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0035357 peroxisome proliferator activated receptor signaling pathway IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045994 positive regulation of translational initiation by iron IEA
 biological_processGO:0048384 retinoic acid receptor signaling pathway IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis IEA
 biological_processGO:0055012 ventricular cardiac muscle cell differentiation IEA
 biological_processGO:0060038 cardiac muscle cell proliferation IEA
 biological_processGO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development IEA
 biological_processGO:0060687 regulation of branching involved in prostate gland morphogenesis IEA
 biological_processGO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043235 receptor complex IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001972 retinoic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0004886 9-cis retinoic acid receptor activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016922 nuclear receptor binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0031490 chromatin DNA binding IEA
 molecular_functionGO:0042277 peptide binding IEA
 molecular_functionGO:0042809 vitamin D receptor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0044323 retinoic acid-responsive element binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0050692 DBD domain binding IEA
 molecular_functionGO:0050693 LBD domain binding IEA
 molecular_functionGO:0070644 vitamin D response element binding IEA


Pathways (from Reactome)
Pathway description
Recycling of bile acids and salts
Synthesis of bile acids and bile salts
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Import of palmitoyl-CoA into the mitochondrial matrix
Regulation of pyruvate dehydrogenase (PDH) complex
Endogenous sterols
Transcriptional regulation of white adipocyte differentiation
Nuclear Receptor transcription pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
SUMOylation of intracellular receptors
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr