ENSDARG00000052695


Danio rerio

Features
Gene ID: ENSDARG00000052695
  
Biological name :nr2f1a
  
Synonyms : nr2f1a / nuclear receptor subfamily 2, group F, member 1a / Q06725
  
Possible biological names infered from orthology : NR2F1 / nuclear receptor subfamily 2 group F member 1 / P10589
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 49744713
Gene end: 49751549
  
Corresponding Affymetrix probe sets: Dr.16.1.S1_at (Zebrafish Array)   NM_131180_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000116750
NCBI entrez gene - 30418     See in Manteia.
RefSeq - XM_005165507
RefSeq - NM_131180
RefSeq Peptide - NP_571255
swissprot - Q06725
ZFIN ID - ZDB-GENE-980526-115
Ensembl - ENSDARG00000052695
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NR2F1ENSGALG00000027907Gallus gallus
 NR2F1ENSG00000175745Homo sapiens
 Nr2f1ENSMUSG00000069171Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nr2f2 / nuclear receptor subfamily 2, group F, member 2 / P24468* / P43135*ENSDARG0000004092686
nr2f1b / Q6PH18 / nuclear receptor subfamily 2, group F, member 1bENSDARG0000001716882
nr2f5 / Q06726 / nuclear receptor subfamily 2, group F, member 5ENSDARG0000003317276
nr2f6a / nuclear receptor subfamily 2, group F, member 6a / NR2F6* / P43136* / P10588* / nuclear receptor subfamily 2 group F member 6*ENSDARG0000000360761
nr2f6b / nuclear receptor subfamily 2, group F, member 6b / NR2F6* / P43136* / P10588* / nuclear receptor subfamily 2 group F member 6*ENSDARG0000000316561
rxrgb / Q6DHP9 / retinoid X receptor, gamma b / RXRG* / P28705* / P48443* / retinoid X receptor gamma* / Retinoic acid receptor RXR-gamma *ENSDARG0000000469737
rxraa / retinoid X receptor, alpha a / RXRA* / P19793* / P28700* / retinoid X receptor alpha*ENSDARG0000005773737
nr2c2 / nuclear receptor subfamily 2, group C, member 2 / P49116* / P49117*ENSDARG0000004247736
rxrba / Q7SYN5 / retinoid x receptor, beta a / RXRB* / P28704* / P28702* / retinoid X receptor beta*ENSDARG0000007895436
nr2e3 / nuclear receptor subfamily 2, group E, member 3 / Q9QXZ7* / Q9Y5X4* / Photoreceptor-specific nuclear receptor *ENSDARG0000004590435
rxrab / retinoid x receptor, alpha b / RXRA* / P19793* / P28700* / retinoid X receptor alpha*ENSDARG0000003512735
rxrbb / retinoid x receptor, beta b / RXRB* / P28702* / P28704* / retinoid X receptor beta*ENSDARG0000000200635
nr2c1 / nuclear receptor subfamily 2, group C, member 1 / P13056* / Q505F1*ENSDARG0000004552733
nr2e1 / nuclear receptor subfamily 2, group E, member 1 / Q64104* / Q9Y466*ENSDARG0000001710733
hnf4a / hepatocyte nuclear factor 4, alpha / P41235* / P49698*ENSDARG0000002149432
hnf4g / hepatocyte nuclear factor 4, gamma / Q14541*ENSDARG0000007156529
CABZ01057488.1ENSDARG0000010474223


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003068  Transcription factor COUP
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001935 endothelial cell proliferation IMP
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel endothelial cell decreased amount , abnormal
intersegmental vessel arrested , abnormal
Show

 ZFA:0001286 caudal vein plexus caudal vein plexus structure , abnormal
Show

 ZFA:0005024 trunk vasculature trunk vasculature blood circulation disrupted , abnormal
Show

 ZFA:0005295 axial blood vessel axial blood vessel blood circulation disrupted , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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