ENSDARG00000038363


Danio rerio

Features
Gene ID: ENSDARG00000038363
  
Biological name :drd4a
  
Synonyms : dopamine receptor D4a / drd4a
  
Possible biological names infered from orthology : D(4) dopamine receptor / dopamine receptor D4 / DRD4 / P21917 / P51436
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 4707173
Gene end: 4733221
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000128545
Ensembl peptide - ENSDARP00000006774
Ensembl peptide - ENSDARP00000137479
Ensembl peptide - ENSDARP00000148666
NCBI entrez gene - 503564     See in Manteia.
RefSeq - NM_001012616
RefSeq Peptide - NP_001012634
swissprot - F1QH78
swissprot - A0A0R4IR92
swissprot - Q5DJ16
swissprot - X1WE94
ZFIN ID - ZDB-GENE-070112-996
Ensembl - ENSDARG00000038363
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DRD4ENSGALG00000040761Gallus gallus
 DRD4ENSG00000069696Homo sapiens
 Drd4ENSMUSG00000025496Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
drd4b / dopamine receptor D4b / DRD4* / P51436* / P21917* / dopamine receptor D4* / D(4) dopamine receptor *ENSDARG0000003582074
drd4-rs / dopamine receptor D4 related sequenceENSDARG0000000191255
drd2b / dopamine receptor D2b / DRD2* / P61168* / P14416* / dopamine receptor D2* / D(2) dopamine receptor *ENSDARG0000001109140
drd2a / dopamine receptor D2a / DRD2* / P61168* / P14416* / dopamine receptor D2* / D(2) dopamine receptor *ENSDARG0000005692638
drd2l / dopamine receptor D2 likeENSDARG0000001485838
drd3 / dopamine receptor D3 / P30728* / P35462* / D(3) dopamine receptor *ENSDARG0000003213136
hrh2b / histamine receptor H2b / HRH2* / P25021* / P97292* / histamine receptor H2* / Histamine H2 receptor *ENSDARG0000005747928
adrb3a / adrenoceptor beta 3a / ADRB3* / P25962* / P13945* / adrenoceptor beta 3* / Beta-3 adrenergic receptor *ENSDARG0000005364627
BX530018.1 / DRD5* / P21918* / dopamine receptor D5*ENSDARG0000003757627
hrh2a / histamine receptor H2a / HRH2* / P25021* / histamine receptor H2*ENSDARG0000010744427
drd1b / dopamine receptor D1b / DRD1* / P21728* / dopamine receptor D1*ENSDARG0000003891827
drd1a / dopamine receptor D1a / DRD1* / Q61616* / P21728* / dopamine receptor D1* / D(1A) dopamine receptor *ENSDARG0000007164027
htr2ab / 5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate b / HTR2A* / P35363* / P28223* / 5-hydroxytryptamine receptor 2A* / 5-hydroxytryptamine (serotonin) receptor 2A*ENSDARG0000005816527
AL935174.5ENSDARG0000011512926
drd7 / dopamine receptor D7ENSDARG0000005628426
adrb1 / adrenoceptor beta 1 / P08588* / P34971* / Beta-1 adrenergic receptor *ENSDARG0000000749026
drd6b / dopamine receptor D6bENSDARG0000004076526
adrb3b / adrenoceptor beta 3b / ADRB3* / P25962* / P13945* / adrenoceptor beta 3* / Beta-3 adrenergic receptor *ENSDARG0000005291925
htr2b / 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled / P41595* / 5-hydroxytryptamine receptor 2B*ENSDARG0000011592525
htr2cl1 / 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 / HTR2C* / P34968* / P28335* / 5-hydroxytryptamine receptor 2C* / 5-hydroxytryptamine (serotonin) receptor 2C*ENSDARG0000001822825


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000929  Dopamine receptor family
 IPR002185  Dopamine D4 receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway IEA
 biological_processGO:0007212 dopamine receptor signaling pathway IEA
 biological_processGO:0021514 ventral spinal cord interneuron differentiation IMP
 biological_processGO:0021520 spinal cord motor neuron cell fate specification IMP
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004952 dopamine neurotransmitter receptor activity IEA


Pathways (from Reactome)
Pathway description
Dopamine receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord motor neuron increased amount , abnormal
spinal cord motor neuron decreased amount , abnormal
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 ZFA:0000778 spinal cord interneuron spinal cord interneuron increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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