ENSDARG00000115925


Danio rerio

Features
Gene ID: ENSDARG00000115925
  
Biological name :htr2b
  
Synonyms : 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled / htr2b
  
Possible biological names infered from orthology : 5-hydroxytryptamine receptor 2B / 5-hydroxytryptamine (serotonin) receptor 2B / P41595 / Q02152
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 37671430
Gene end: 37686966
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000147603
NCBI entrez gene - 751784     See in Manteia.
RefSeq - NM_001044743
RefSeq Peptide - NP_001038208
swissprot - Q0GH74
ZFIN ID - ZDB-GENE-081022-57
Ensembl - ENSDARG00000115925
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HTR2BENSGALG00000007681Gallus gallus
 HTR2BENSG00000135914Homo sapiens
 Htr2bENSMUSG00000026228Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
htr2cl1 / 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 / HTR2C* / P34968* / P28335* / 5-hydroxytryptamine receptor 2C* / 5-hydroxytryptamine (serotonin) receptor 2C*ENSDARG0000001822844
htr2aa / 5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a / HTR2A* / P35363* / P28223* / 5-hydroxytryptamine receptor 2A* / 5-hydroxytryptamine (serotonin) receptor 2A*ENSDARG0000005702944
htr2ab / 5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate b / HTR2A* / P35363* / P28223* / 5-hydroxytryptamine receptor 2A* / 5-hydroxytryptamine (serotonin) receptor 2A*ENSDARG0000005816542
htr2cl2 / 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 2ENSDARG0000001321039
drd2b / dopamine receptor D2b / DRD2* / P61168* / P14416* / dopamine receptor D2* / D(2) dopamine receptor *ENSDARG0000001109126
drd2a / dopamine receptor D2a / DRD2* / P61168* / P14416* / dopamine receptor D2* / D(2) dopamine receptor *ENSDARG0000005692626
drd3 / dopamine receptor D3 / P30728* / P35462* / D(3) dopamine receptor *ENSDARG0000003213125
drd4-rs / dopamine receptor D4 related sequenceENSDARG0000000191225
drd2l / dopamine receptor D2 likeENSDARG0000001485824
adrb1 / adrenoceptor beta 1 / P08588* / P34971* / Beta-1 adrenergic receptor *ENSDARG0000000749024
drd4b / dopamine receptor D4b / DRD4* / P51436* / P21917* / dopamine receptor D4* / D(4) dopamine receptor *ENSDARG0000003582023
AL935174.5ENSDARG0000011512923
drd1b / dopamine receptor D1b / DRD1* / P21728* / dopamine receptor D1*ENSDARG0000003891823
adrb3a / adrenoceptor beta 3a / ADRB3* / P25962* / P13945* / adrenoceptor beta 3* / Beta-3 adrenergic receptor *ENSDARG0000005364623
hrh2a / histamine receptor H2a / HRH2* / P25021* / histamine receptor H2*ENSDARG0000010744422
adrb3b / adrenoceptor beta 3b / ADRB3* / P25962* / P13945* / adrenoceptor beta 3* / Beta-3 adrenergic receptor *ENSDARG0000005291922
drd7 / dopamine receptor D7ENSDARG0000005628422
BX530018.1 / DRD5* / P21918* / dopamine receptor D5*ENSDARG0000003757622
htr6 / 5-hydroxytryptamine (serotonin) receptor 6 / P50406* / Q9R1C8* / 5-hydroxytryptamine receptor 6*ENSDARG0000001609522
adrb2a / adrenoceptor beta 2, surface a / ADRB2* / P18762* / P07550* / adrenoceptor beta 2* / Beta-2 adrenergic receptor *ENSDARG0000008812422


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000482  5-Hydroxytryptamine 2B receptor
 IPR002231  5-hydroxytryptamine receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006939 smooth muscle contraction IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0042310 vasoconstriction IEA
 biological_processGO:0042493 response to drug IBA
 biological_processGO:0050795 regulation of behavior IEA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IBA
 biological_processGO:0098664 G-protein coupled serotonin receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004993 G-protein coupled serotonin receptor activity IBA
 molecular_functionGO:0030594 neurotransmitter receptor activity IBA


Pathways (from Reactome)
Pathway description
Serotonin receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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