ENSDARG00000052919


Danio rerio

Features
Gene ID: ENSDARG00000052919
  
Biological name :adrb3b
  
Synonyms : adrb3b / adrenoceptor beta 3b
  
Possible biological names infered from orthology : ADRB3 / adrenoceptor beta 3 / Beta-3 adrenergic receptor / P13945 / P25962
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 41199660
Gene end: 41214668
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000108055
NCBI entrez gene - 792519     See in Manteia.
swissprot - B3DIE4
ZFIN ID - ZDB-GENE-081022-154
Ensembl - ENSDARG00000052919
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADRB3ENSGALG00000019018Gallus gallus
 ADRB3ENSG00000188778Homo sapiens
 Adrb3ENSMUSG00000031489Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adrb3a / adrenoceptor beta 3a / ADRB3* / P25962* / P13945* / adrenoceptor beta 3* / Beta-3 adrenergic receptor *ENSDARG0000005364647
adrb1 / adrenoceptor beta 1 / P08588* / P34971* / Beta-1 adrenergic receptor *ENSDARG0000000749042
adrb2a / adrenoceptor beta 2, surface a / ADRB2* / P18762* / P07550* / adrenoceptor beta 2* / Beta-2 adrenergic receptor *ENSDARG0000008812438
adrb2b / adrenoceptor beta 2, surface b / ADRB2* / P18762* / P07550* / adrenoceptor beta 2* / Beta-2 adrenergic receptor *ENSDARG0000005451037
hrh2a / histamine receptor H2a / HRH2* / P25021* / histamine receptor H2*ENSDARG0000010744429
BX530018.1 / DRD5* / P21918* / dopamine receptor D5*ENSDARG0000003757629
drd1b / dopamine receptor D1b / DRD1* / P21728* / dopamine receptor D1*ENSDARG0000003891828
drd1a / dopamine receptor D1a / DRD1* / Q61616* / P21728* / dopamine receptor D1* / D(1A) dopamine receptor *ENSDARG0000007164028
drd7 / dopamine receptor D7ENSDARG0000005628428
AL935174.5ENSDARG0000011512927
drd6b / dopamine receptor D6bENSDARG0000004076527
hrh2b / histamine receptor H2b / HRH2* / P25021* / P97292* / histamine receptor H2* / Histamine H2 receptor *ENSDARG0000005747925
drd2b / dopamine receptor D2b / DRD2* / P61168* / P14416* / dopamine receptor D2* / D(2) dopamine receptor *ENSDARG0000001109125
drd4-rs / dopamine receptor D4 related sequenceENSDARG0000000191225
drd2a / dopamine receptor D2a / DRD2* / P61168* / P14416* / dopamine receptor D2* / D(2) dopamine receptor *ENSDARG0000005692625
drd3 / dopamine receptor D3 / P30728* / P35462* / D(3) dopamine receptor *ENSDARG0000003213125
htr2b / 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled / P41595* / 5-hydroxytryptamine receptor 2B*ENSDARG0000011592524
drd2l / dopamine receptor D2 likeENSDARG0000001485824
htr2cl1 / 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 / HTR2C* / P34968* / P28335* / 5-hydroxytryptamine receptor 2C* / 5-hydroxytryptamine (serotonin) receptor 2C*ENSDARG0000001822823
drd4b / dopamine receptor D4b / DRD4* / P51436* / P21917* / dopamine receptor D4* / D(4) dopamine receptor *ENSDARG0000003582023


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001659 temperature homeostasis IBA
 biological_processGO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0015052 beta3-adrenergic receptor activity IBA
 molecular_functionGO:0051379 epinephrine binding IBA
 molecular_functionGO:0051380 norepinephrine binding IBA


Pathways (from Reactome)
Pathway description
Adrenoceptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism viability , abnormal
Show

 ZFA:0001114 head head malformed , abnormal
head shape , abnormal
Show

 ZFA:0001115 trunk trunk shape , abnormal
Show

 ZFA:0001167 vertebra 1 vertebra 1 malformed , abnormal
Show

 ZFA:0001168 vertebra 2 vertebra 2 malformed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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