Manteia

ENSGALG00000019018

Gallus gallus

Features

Gene ID:	ENSGALG00000019018

Biological name :	ADRB3

Synonyms :	ADRB3 / adrenoceptor beta 3

Possible biological names infered from orthology :	Beta-3 adrenergic receptor / P13945 / P25962

Species:	Gallus gallus

Chr. number:	22
Strand:	-1
Band:
Gene start:	2263412
Gene end:	2265233

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSGALP00000029364 swissprot - E1C4B7 Ensembl - ENSGALG00000019018

See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
adrb3a	ENSDARG00000053646	Danio rerio
adrb3b	ENSDARG00000052919	Danio rerio
ADRB3	ENSG00000188778	Homo sapiens
Adrb3	ENSMUSG00000031489	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
ADRB1 / adrenoceptor beta 1 / P08588* / P34971* / Beta-1 adrenergic receptor *	ENSGALG00000008949	42
ADRB2 / adrenoceptor beta 2 / P07550* / P18762* / Beta-2 adrenergic receptor *	ENSGALG00000040035	37
DRD5 / dopamine receptor D5 / P21918* / Q8BLD9* / D(1B) dopamine receptor *	ENSGALG00000014975	25
DD1CR / dopamine D1C receptor	ENSGALG00000006540	25
DRD1 / dopamine receptor D1 / P21728* / Q61616* / D(1A) dopamine receptor *	ENSGALG00000039698	24
HTR6 / 5-hydroxytryptamine receptor 6 / P50406* / Q9R1C8* / 5-hydroxytryptamine (serotonin) receptor 6*	ENSGALG00000004066	24
	ENSGALG00000015953	21
DRD2 / dopamine receptor D2 / P14416* / P61168* / D(2) dopamine receptor *	ENSGALG00000007794	21
DRD3 / dopamine receptor D3 / P30728* / P35462* / D(3) dopamine receptor *	ENSGALG00000015117	21
HRH2 / histamine receptor H2 / P25021* / P97292* / Histamine H2 receptor *	ENSGALG00000024171	21
HTR2B / 5-hydroxytryptamine receptor 2B / P41595* / Q02152* / 5-hydroxytryptamine (serotonin) receptor 2B*	ENSGALG00000007681	20
HTR2C / Gallus gallus 5-hydroxytryptamine receptor 2C (HTR2C), mRNA. / P28335* / P34968* / 5-hydroxytryptamine receptor 2C* / 5-hydroxytryptamine (serotonin) receptor 2C*	ENSGALG00000005853	19
DRD4 / dopamine receptor D4 / P21917* / P51436* / D(4) dopamine receptor *	ENSGALG00000040761	19
HTR2A / Gallus gallus 5-hydroxytryptamine receptor 2A (HTR2A), mRNA. / P28223* / P35363* / 5-hydroxytryptamine receptor 2A* / 5-hydroxytryptamine (serotonin) receptor 2A*	ENSGALG00000016992	19

Protein motifs (from Interpro)

Interpro ID	Name
IPR000276	G protein-coupled receptor, rhodopsin-like
IPR000507	Beta 1 adrenoceptor
IPR002233	Adrenoceptor family
IPR017452	GPCR, rhodopsin-like, 7TM

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001659	temperature homeostasis	IBA
biological_process	GO:0002024	diet induced thermogenesis	IEA
biological_process	GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure	IEA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007190	activation of adenylate cyclase activity	IEA
biological_process	GO:0007267	cell-cell signaling	IBA
biological_process	GO:0009409	response to cold	IEA
biological_process	GO:0031649	heat generation	IEA
biological_process	GO:0040015	negative regulation of multicellular organism growth	IEA
biological_process	GO:0043410	positive regulation of MAPK cascade	IEA
biological_process	GO:0045823	positive regulation of heart contraction	IEA
biological_process	GO:0050873	brown fat cell differentiation	IEA
biological_process	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	IBA
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0005887	integral component of plasma membrane	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0043235	receptor complex	IEA
molecular_function	GO:0004871	obsolete signal transducer activity	IEA
molecular_function	GO:0004930	G-protein coupled receptor activity	IEA
molecular_function	GO:0004935	adrenergic receptor activity	IEA
molecular_function	GO:0004939	beta-adrenergic receptor activity	IEA
molecular_function	GO:0004940	beta1-adrenergic receptor activity	IEA
molecular_function	GO:0015052	beta3-adrenergic receptor activity	IEA
molecular_function	GO:0031699	beta-3 adrenergic receptor binding	IEA
molecular_function	GO:0042803	protein homodimerization activity	IEA
molecular_function	GO:0051379	epinephrine binding	IBA
molecular_function	GO:0051380	norepinephrine binding	IEA

Pathways (from Reactome)

Pathway description

Adrenoceptors

G alpha (s) signalling events

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr