ENSGALG00000007794


Gallus gallus

Features
Gene ID: ENSGALG00000007794
  
Biological name :DRD2
  
Synonyms : dopamine receptor D2 / DRD2
  
Possible biological names infered from orthology : D(2) dopamine receptor / P14416 / P61168
  
Species: Gallus gallus
  
Chr. number: 24
Strand: 1
Band:
Gene start: 5726541
Gene end: 5731611
  
Corresponding Affymetrix probe sets: GgaAffx.4862.1.S1_at (Chicken Array)   GgaAffx.4862.3.S1_at (Chicken Array)   GgaAffx.4862.4.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012625
Ensembl peptide - ENSGALP00000055205
Ensembl peptide - ENSGALP00000050761
NCBI entrez gene - 428252     See in Manteia.
RefSeq - NM_001113290
RefSeq - XM_015298029
RefSeq - XM_015298031
RefSeq Peptide - NP_001106761
swissprot - A9YZQ5
swissprot - A0A1D5PQP0
swissprot - A0A1D5PDB7
Ensembl - ENSGALG00000007794
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 drd2aENSDARG00000056926Danio rerio
 drd2bENSDARG00000011091Danio rerio
 DRD2ENSG00000149295Homo sapiens
 Drd2ENSMUSG00000032259Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DRD3 / dopamine receptor D3 / P30728* / P35462* / D(3) dopamine receptor *ENSGALG0000001511748
DRD4 / dopamine receptor D4 / P21917* / P51436* / D(4) dopamine receptor *ENSGALG0000004076135
DRD5 / dopamine receptor D5 / P21918* / Q8BLD9* / D(1B) dopamine receptor *ENSGALG0000001497528
HTR2B / 5-hydroxytryptamine receptor 2B / P41595* / Q02152* / 5-hydroxytryptamine (serotonin) receptor 2B*ENSGALG0000000768127
DD1CR / dopamine D1C receptor ENSGALG0000000654027
DRD1 / dopamine receptor D1 / P21728* / Q61616* / D(1A) dopamine receptor *ENSGALG0000003969827
HRH2 / histamine receptor H2 / P25021* / P97292* / Histamine H2 receptor *ENSGALG0000002417127
ENSGALG0000001595326
HTR2C / Gallus gallus 5-hydroxytryptamine receptor 2C (HTR2C), mRNA. / P28335* / P34968* / 5-hydroxytryptamine receptor 2C* / 5-hydroxytryptamine (serotonin) receptor 2C*ENSGALG0000000585326
HTR2A / Gallus gallus 5-hydroxytryptamine receptor 2A (HTR2A), mRNA. / P28223* / P35363* / 5-hydroxytryptamine receptor 2A* / 5-hydroxytryptamine (serotonin) receptor 2A*ENSGALG0000001699226
ADRB2 / adrenoceptor beta 2 / P07550* / P18762* / Beta-2 adrenergic receptor *ENSGALG0000004003525
ADRB1 / adrenoceptor beta 1 / P08588* / P34971* / Beta-1 adrenergic receptor *ENSGALG0000000894925
ADRB3 / adrenoceptor beta 3 / P13945* / P25962* / Beta-3 adrenergic receptor *ENSGALG0000001901824
HTR6 / 5-hydroxytryptamine receptor 6 / P50406* / Q9R1C8* / 5-hydroxytryptamine (serotonin) receptor 6*ENSGALG0000000406623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000929  Dopamine receptor family
 IPR001922  Dopamine D2 receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001659 temperature homeostasis IEA
 biological_processGO:0001661 conditioned taste aversion IDA
 biological_processGO:0001963 synaptic transmission, dopaminergic IBA
 biological_processGO:0001964 startle response IEA
 biological_processGO:0001975 response to amphetamine IEA
 biological_processGO:0001976 neurological system process involved in regulation of systemic arterial blood pressure IEA
 biological_processGO:0002027 regulation of heart rate IEA
 biological_processGO:0002028 regulation of sodium ion transport IEA
 biological_processGO:0002052 positive regulation of neuroblast proliferation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007194 negative regulation of adenylate cyclase activity IBA
 biological_processGO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway IEA
 biological_processGO:0007212 dopamine receptor signaling pathway IEA
 biological_processGO:0007270 neuron-neuron synaptic transmission IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0007608 sensory perception of smell IEA
 biological_processGO:0007625 grooming behavior IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0007628 adult walking behavior IEA
 biological_processGO:0007631 feeding behavior IEA
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0008542 visual learning IEA
 biological_processGO:0009416 response to light stimulus IEA
 biological_processGO:0009636 response to toxic substance IBA
 biological_processGO:0014059 regulation of dopamine secretion IEA
 biological_processGO:0021853 cerebral cortex GABAergic interneuron migration IEA
 biological_processGO:0021984 adenohypophysis development IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0030432 peristalsis IEA
 biological_processGO:0030534 adult behavior IEA
 biological_processGO:0032228 regulation of synaptic transmission, GABAergic IEA
 biological_processGO:0032467 positive regulation of cytokinesis IEA
 biological_processGO:0032922 circadian regulation of gene expression IEA
 biological_processGO:0034776 response to histamine IEA
 biological_processGO:0035810 positive regulation of urine volume IEA
 biological_processGO:0035815 positive regulation of renal sodium excretion IEA
 biological_processGO:0040018 positive regulation of multicellular organism growth IEA
 biological_processGO:0042220 response to cocaine IEA
 biological_processGO:0042417 dopamine metabolic process IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043266 regulation of potassium ion transport IEA
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0043473 pigmentation IEA
 biological_processGO:0045776 negative regulation of blood pressure IEA
 biological_processGO:0045824 negative regulation of innate immune response IEA
 biological_processGO:0048148 behavioral response to cocaine IEA
 biological_processGO:0048149 behavioral response to ethanol IEA
 biological_processGO:0048169 regulation of long-term neuronal synaptic plasticity IEA
 biological_processGO:0048755 branching morphogenesis of a nerve IEA
 biological_processGO:0050482 arachidonic acid secretion IEA
 biological_processGO:0050709 negative regulation of protein secretion IEA
 biological_processGO:0050804 modulation of chemical synaptic transmission IEA
 biological_processGO:0051481 negative regulation of cytosolic calcium ion concentration IBA
 biological_processGO:0051584 regulation of dopamine uptake involved in synaptic transmission IEA
 biological_processGO:0051586 positive regulation of dopamine uptake involved in synaptic transmission IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 biological_processGO:0051967 negative regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:0060124 positive regulation of growth hormone secretion IEA
 biological_processGO:0060134 prepulse inhibition IEA
 biological_processGO:0060158 phospholipase C-activating dopamine receptor signaling pathway IEA
 biological_processGO:0060160 negative regulation of dopamine receptor signaling pathway IEA
 biological_processGO:1900168 positive regulation of glial cell-derived neurotrophic factor secretion IEA
 biological_processGO:1901386 negative regulation of voltage-gated calcium channel activity IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IBA
 cellular_componentGO:0060170 ciliary membrane IEA
 cellular_componentGO:0097730 non-motile cilium IEA
 molecular_functionGO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004952 dopamine neurotransmitter receptor activity IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0035240 dopamine binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0097159 organic cyclic compound binding IDA


Pathways (from Reactome)
Pathway description
Dopamine receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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