Manteia

ENSGALG00000040035

Gallus gallus

Features

Gene ID:	ENSGALG00000040035

Biological name :	ADRB2

Synonyms :	ADRB2 / adrenoceptor beta 2

Possible biological names infered from orthology :	Beta-2 adrenergic receptor / P07550 / P18762

Species:	Gallus gallus

Chr. number:	13
Strand:	-1
Band:
Gene start:	8649968
Gene end:	8651161

Corresponding Affymetrix probe sets:	GgaAffx.1818.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000048596 swissprot - A0A1D5P7A9 Ensembl - ENSGALG00000040035

See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
adrb2a	ENSDARG00000088124	Danio rerio
adrb2b	ENSDARG00000054510	Danio rerio
ADRB2	ENSG00000169252	Homo sapiens
Adrb2	ENSMUSG00000045730	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
ADRB1 / adrenoceptor beta 1 / P08588* / P34971* / Beta-1 adrenergic receptor *	ENSGALG00000008949	51
ADRB3 / adrenoceptor beta 3 / P13945* / P25962* / Beta-3 adrenergic receptor *	ENSGALG00000019018	48
DRD5 / dopamine receptor D5 / P21918* / Q8BLD9* / D(1B) dopamine receptor *	ENSGALG00000014975	33
DRD1 / dopamine receptor D1 / P21728* / Q61616* / D(1A) dopamine receptor *	ENSGALG00000039698	32
DD1CR / dopamine D1C receptor	ENSGALG00000006540	31
HTR6 / 5-hydroxytryptamine receptor 6 / P50406* / Q9R1C8* / 5-hydroxytryptamine (serotonin) receptor 6*	ENSGALG00000004066	28
DRD2 / dopamine receptor D2 / P14416* / P61168* / D(2) dopamine receptor *	ENSGALG00000007794	28
HRH2 / histamine receptor H2 / P25021* / P97292* / Histamine H2 receptor *	ENSGALG00000024171	27
	ENSGALG00000015953	26
DRD3 / dopamine receptor D3 / P30728* / P35462* / D(3) dopamine receptor *	ENSGALG00000015117	25
HTR2B / 5-hydroxytryptamine receptor 2B / P41595* / Q02152* / 5-hydroxytryptamine (serotonin) receptor 2B*	ENSGALG00000007681	25
HTR2A / Gallus gallus 5-hydroxytryptamine receptor 2A (HTR2A), mRNA. / P28223* / P35363* / 5-hydroxytryptamine receptor 2A* / 5-hydroxytryptamine (serotonin) receptor 2A*	ENSGALG00000016992	24
HTR2C / Gallus gallus 5-hydroxytryptamine receptor 2C (HTR2C), mRNA. / P28335* / P34968* / 5-hydroxytryptamine receptor 2C* / 5-hydroxytryptamine (serotonin) receptor 2C*	ENSGALG00000005853	24
DRD4 / dopamine receptor D4 / P21917* / P51436* / D(4) dopamine receptor *	ENSGALG00000040761	23

Protein motifs (from Interpro)

Interpro ID	Name
IPR000276	G protein-coupled receptor, rhodopsin-like
IPR000332	Beta 2 adrenoceptor
IPR002233	Adrenoceptor family
IPR017452	GPCR, rhodopsin-like, 7TM

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	IEA
biological_process	GO:0002024	diet induced thermogenesis	IEA
biological_process	GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure	IEA
biological_process	GO:0002028	regulation of sodium ion transport	IEA
biological_process	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin	IEA
biological_process	GO:0006898	receptor-mediated endocytosis	IEA
biological_process	GO:0006940	regulation of smooth muscle contraction	IEA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007190	activation of adenylate cyclase activity	IEA
biological_process	GO:0009409	response to cold	IEA
biological_process	GO:0010739	positive regulation of protein kinase A signaling	IEA
biological_process	GO:0030501	positive regulation of bone mineralization	IEA
biological_process	GO:0031398	positive regulation of protein ubiquitination	IEA
biological_process	GO:0031649	heat generation	IEA
biological_process	GO:0040015	negative regulation of multicellular organism growth	IEA
biological_process	GO:0043410	positive regulation of MAPK cascade	IEA
biological_process	GO:0045453	bone resorption	IEA
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	IEA
biological_process	GO:0045986	negative regulation of smooth muscle contraction	IEA
biological_process	GO:0050873	brown fat cell differentiation	IEA
biological_process	GO:0061885	positive regulation of mini excitatory postsynaptic potential	IEA
biological_process	GO:0071875	adrenergic receptor signaling pathway	IEA
biological_process	GO:0071902	positive regulation of protein serine/threonine kinase activity	IEA
biological_process	GO:0097746	regulation of blood vessel diameter	IEA
biological_process	GO:1901098	positive regulation of autophagosome maturation	IEA
biological_process	GO:1904504	positive regulation of lipophagy	IEA
biological_process	GO:1904646	cellular response to amyloid-beta	IEA
biological_process	GO:2000969	positive regulation of AMPA receptor activity	IEA
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0005887	integral component of plasma membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0016324	apical plasma membrane	IEA
cellular_component	GO:0043235	receptor complex	IEA
molecular_function	GO:0001540	amyloid-beta binding	IEA
molecular_function	GO:0004871	obsolete signal transducer activity	IEA
molecular_function	GO:0004930	G-protein coupled receptor activity	IEA
molecular_function	GO:0004935	adrenergic receptor activity	IEA
molecular_function	GO:0004941	beta2-adrenergic receptor activity	IEA
molecular_function	GO:0008179	adenylate cyclase binding	IEA
molecular_function	GO:0015459	potassium channel regulator activity	IEA
molecular_function	GO:0019899	enzyme binding	IEA
molecular_function	GO:0042803	protein homodimerization activity	IEA
molecular_function	GO:0044877	protein-containing complex binding	IEA
molecular_function	GO:0051380	norepinephrine binding	IEA

Pathways (from Reactome)

Pathway description

Adrenoceptors

G alpha (s) signalling events

Ub-specific processing proteases

Cargo recognition for clathrin-mediated endocytosis

Clathrin-mediated endocytosis

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr