ENSDARG00000088124


Danio rerio

Features
Gene ID: ENSDARG00000088124
  
Biological name :adrb2a
  
Synonyms : adrb2a / adrenoceptor beta 2, surface a
  
Possible biological names infered from orthology : ADRB2 / adrenoceptor beta 2 / Beta-2 adrenergic receptor / P07550 / P18762
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 34825465
Gene end: 34830615
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000130127
swissprot - E7EYN4
ZFIN ID - ZDB-GENE-100414-3
Ensembl - ENSDARG00000088124
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADRB2ENSGALG00000040035Gallus gallus
 ADRB2ENSG00000169252Homo sapiens
 Adrb2ENSMUSG00000045730Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adrb2b / adrenoceptor beta 2, surface b / ADRB2* / P18762* / P07550* / adrenoceptor beta 2* / Beta-2 adrenergic receptor *ENSDARG0000005451056
adrb1 / adrenoceptor beta 1 / P08588* / P34971* / Beta-1 adrenergic receptor *ENSDARG0000000749046
adrb3a / adrenoceptor beta 3a / ADRB3* / P25962* / P13945* / adrenoceptor beta 3* / Beta-3 adrenergic receptor *ENSDARG0000005364639
adrb3b / adrenoceptor beta 3b / ADRB3* / P25962* / P13945* / adrenoceptor beta 3* / Beta-3 adrenergic receptor *ENSDARG0000005291938
drd1b / dopamine receptor D1b / DRD1* / P21728* / dopamine receptor D1*ENSDARG0000003891832
drd6b / dopamine receptor D6bENSDARG0000004076531
AL935174.5ENSDARG0000011512930
drd1a / dopamine receptor D1a / DRD1* / Q61616* / P21728* / dopamine receptor D1* / D(1A) dopamine receptor *ENSDARG0000007164029
BX530018.1 / DRD5* / P21918* / dopamine receptor D5*ENSDARG0000003757629
drd7 / dopamine receptor D7ENSDARG0000005628428
hrh2a / histamine receptor H2a / HRH2* / P25021* / histamine receptor H2*ENSDARG0000010744428
drd3 / dopamine receptor D3 / P30728* / P35462* / D(3) dopamine receptor *ENSDARG0000003213126
drd2a / dopamine receptor D2a / DRD2* / P61168* / P14416* / dopamine receptor D2* / D(2) dopamine receptor *ENSDARG0000005692626
drd2b / dopamine receptor D2b / DRD2* / P61168* / P14416* / dopamine receptor D2* / D(2) dopamine receptor *ENSDARG0000001109126
htr2cl1 / 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 / HTR2C* / P34968* / P28335* / 5-hydroxytryptamine receptor 2C* / 5-hydroxytryptamine (serotonin) receptor 2C*ENSDARG0000001822824
htr2b / 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled / P41595* / 5-hydroxytryptamine receptor 2B*ENSDARG0000011592524
htr6 / 5-hydroxytryptamine (serotonin) receptor 6 / P50406* / Q9R1C8* / 5-hydroxytryptamine receptor 6*ENSDARG0000001609524
drd2l / dopamine receptor D2 likeENSDARG0000001485823
htr2cl2 / 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 2ENSDARG0000001321023
drd4-rs / dopamine receptor D4 related sequenceENSDARG0000000191223


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000332  Beta 2 adrenoceptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure IBA
 biological_processGO:0002027 regulation of heart rate IMP
 biological_processGO:0006940 regulation of smooth muscle contraction IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0045986 negative regulation of smooth muscle contraction IBA
 biological_processGO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway IBA
 biological_processGO:0097746 regulation of blood vessel diameter IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004935 adrenergic receptor activity IEA
 molecular_functionGO:0004941 beta2-adrenergic receptor activity IBA
 molecular_functionGO:0051379 epinephrine binding IBA


Pathways (from Reactome)
Pathway description
Adrenoceptors
G alpha (s) signalling events
Ub-specific processing proteases
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000084 yolk yolk width , abnormal
Show

 ZFA:0000368 integument integument melanosome decreased size , abnormal
integument melanosome variant shape , abnormal
integument melanosome decreased amount , abnormal
integument melanosome decreased pigmentation , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr