ENSDARG00000054510


Danio rerio

Features
Gene ID: ENSDARG00000054510
  
Biological name :adrb2b
  
Synonyms : adrb2b / adrenoceptor beta 2, surface b
  
Possible biological names infered from orthology : ADRB2 / adrenoceptor beta 2 / Beta-2 adrenergic receptor / P07550 / P18762
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 35078766
Gene end: 35082715
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000112597
NCBI entrez gene - 100037315     See in Manteia.
RefSeq - NM_001089471
RefSeq Peptide - NP_001082940
swissprot - F1QBF9
ZFIN ID - ZDB-GENE-070410-32
Ensembl - ENSDARG00000054510
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADRB2ENSGALG00000040035Gallus gallus
 ADRB2ENSG00000169252Homo sapiens
 Adrb2ENSMUSG00000045730Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adrb2a / adrenoceptor beta 2, surface a / ADRB2* / P18762* / P07550* / adrenoceptor beta 2* / Beta-2 adrenergic receptor *ENSDARG0000008812455
adrb1 / adrenoceptor beta 1 / P08588* / P34971* / Beta-1 adrenergic receptor *ENSDARG0000000749047
adrb3a / adrenoceptor beta 3a / ADRB3* / P25962* / P13945* / adrenoceptor beta 3* / Beta-3 adrenergic receptor *ENSDARG0000005364639
adrb3b / adrenoceptor beta 3b / ADRB3* / P25962* / P13945* / adrenoceptor beta 3* / Beta-3 adrenergic receptor *ENSDARG0000005291937
drd6b / dopamine receptor D6bENSDARG0000004076530
drd1b / dopamine receptor D1b / DRD1* / P21728* / dopamine receptor D1*ENSDARG0000003891830
drd7 / dopamine receptor D7ENSDARG0000005628430
AL935174.5ENSDARG0000011512930
drd1a / dopamine receptor D1a / DRD1* / Q61616* / P21728* / dopamine receptor D1* / D(1A) dopamine receptor *ENSDARG0000007164028
BX530018.1 / DRD5* / P21918* / dopamine receptor D5*ENSDARG0000003757628
drd2a / dopamine receptor D2a / DRD2* / P61168* / P14416* / dopamine receptor D2* / D(2) dopamine receptor *ENSDARG0000005692626
drd2l / dopamine receptor D2 likeENSDARG0000001485825
drd3 / dopamine receptor D3 / P30728* / P35462* / D(3) dopamine receptor *ENSDARG0000003213125
drd2b / dopamine receptor D2b / DRD2* / P61168* / P14416* / dopamine receptor D2* / D(2) dopamine receptor *ENSDARG0000001109125
htr6 / 5-hydroxytryptamine (serotonin) receptor 6 / P50406* / Q9R1C8* / 5-hydroxytryptamine receptor 6*ENSDARG0000001609525
hrh2a / histamine receptor H2a / HRH2* / P25021* / histamine receptor H2*ENSDARG0000010744425
htr2ab / 5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate b / HTR2A* / P35363* / P28223* / 5-hydroxytryptamine receptor 2A* / 5-hydroxytryptamine (serotonin) receptor 2A*ENSDARG0000005816524
htr2b / 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled / P41595* / 5-hydroxytryptamine receptor 2B*ENSDARG0000011592523
htr2cl1 / 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 / HTR2C* / P34968* / P28335* / 5-hydroxytryptamine receptor 2C* / 5-hydroxytryptamine (serotonin) receptor 2C*ENSDARG0000001822823
drd4b / dopamine receptor D4b / DRD4* / P51436* / P21917* / dopamine receptor D4* / D(4) dopamine receptor *ENSDARG0000003582022


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR002233  Adrenoceptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure IBA
 biological_processGO:0002027 regulation of heart rate IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0045986 negative regulation of smooth muscle contraction IBA
 biological_processGO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004935 adrenergic receptor activity IEA
 molecular_functionGO:0004941 beta2-adrenergic receptor activity IBA
 molecular_functionGO:0051379 epinephrine binding IBA


Pathways (from Reactome)
Pathway description
Adrenoceptors
G alpha (s) signalling events
Ub-specific processing proteases
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism edematous , abnormal
whole organism swollen , abnormal
whole organism curled , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk shape , abnormal
Show

 ZFA:0001655 pericardial cavity pericardial cavity increased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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