ENSGALG00000040761


Gallus gallus

Features
Gene ID: ENSGALG00000040761
  
Biological name :DRD4
  
Synonyms : dopamine receptor D4 / DRD4
  
Possible biological names infered from orthology : D(4) dopamine receptor / P21917 / P51436
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 520312
Gene end: 526176
  
Corresponding Affymetrix probe sets: GgaAffx.3186.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052151
NCBI entrez gene - 423016     See in Manteia.
RefSeq - NM_001142849
RefSeq Peptide - NP_001136321
swissprot - B6UVA0
Ensembl - ENSGALG00000040761
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 drd4aENSDARG00000038363Danio rerio
 drd4bENSDARG00000035820Danio rerio
 DRD4ENSG00000069696Homo sapiens
 Drd4ENSMUSG00000025496Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DRD2 / dopamine receptor D2 / P14416* / P61168* / D(2) dopamine receptor *ENSGALG0000000779440
DRD3 / dopamine receptor D3 / P30728* / P35462* / D(3) dopamine receptor *ENSGALG0000001511738
HTR2B / 5-hydroxytryptamine receptor 2B / P41595* / Q02152* / 5-hydroxytryptamine (serotonin) receptor 2B*ENSGALG0000000768129
HRH2 / histamine receptor H2 / P25021* / P97292* / Histamine H2 receptor *ENSGALG0000002417128
DRD1 / dopamine receptor D1 / P21728* / Q61616* / D(1A) dopamine receptor *ENSGALG0000003969827
DRD5 / dopamine receptor D5 / P21918* / Q8BLD9* / D(1B) dopamine receptor *ENSGALG0000001497526
HTR2C / Gallus gallus 5-hydroxytryptamine receptor 2C (HTR2C), mRNA. / P28335* / P34968* / 5-hydroxytryptamine receptor 2C* / 5-hydroxytryptamine (serotonin) receptor 2C*ENSGALG0000000585326
ADRB3 / adrenoceptor beta 3 / P13945* / P25962* / Beta-3 adrenergic receptor *ENSGALG0000001901826
ADRB1 / adrenoceptor beta 1 / P08588* / P34971* / Beta-1 adrenergic receptor *ENSGALG0000000894926
HTR6 / 5-hydroxytryptamine receptor 6 / P50406* / Q9R1C8* / 5-hydroxytryptamine (serotonin) receptor 6*ENSGALG0000000406625
HTR2A / Gallus gallus 5-hydroxytryptamine receptor 2A (HTR2A), mRNA. / P28223* / P35363* / 5-hydroxytryptamine receptor 2A* / 5-hydroxytryptamine (serotonin) receptor 2A*ENSGALG0000001699225
DD1CR / dopamine D1C receptor ENSGALG0000000654025
ADRB2 / adrenoceptor beta 2 / P07550* / P18762* / Beta-2 adrenergic receptor *ENSGALG0000004003524
ENSGALG0000001595323


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000929  Dopamine receptor family
 IPR002185  Dopamine D4 receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0001975 response to amphetamine IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway IEA
 biological_processGO:0007212 dopamine receptor signaling pathway IEA
 biological_processGO:0008344 adult locomotory behavior IEA
 biological_processGO:0032417 positive regulation of sodium:proton antiporter activity IEA
 biological_processGO:0033674 positive regulation of kinase activity IEA
 biological_processGO:0034776 response to histamine IEA
 biological_processGO:0042053 regulation of dopamine metabolic process IEA
 biological_processGO:0042596 fear response IEA
 biological_processGO:0042752 regulation of circadian rhythm IEA
 biological_processGO:0048148 behavioral response to cocaine IEA
 biological_processGO:0050482 arachidonic acid secretion IEA
 biological_processGO:0050709 negative regulation of protein secretion IEA
 biological_processGO:0060080 inhibitory postsynaptic potential IEA
 biological_processGO:1901386 negative regulation of voltage-gated calcium channel activity IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004952 dopamine neurotransmitter receptor activity IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0035240 dopamine binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0051379 epinephrine binding IEA
 molecular_functionGO:0051380 norepinephrine binding IEA


Pathways (from Reactome)
Pathway description
Dopamine receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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