ENSGALG00000005853


Gallus gallus

Features
Gene ID: ENSGALG00000005853
  
Biological name :HTR2C
  
Synonyms : Gallus gallus 5-hydroxytryptamine receptor 2C (HTR2C), mRNA. / HTR2C
  
Possible biological names infered from orthology : 5-hydroxytryptamine receptor 2C / 5-hydroxytryptamine (serotonin) receptor 2C / P28335 / P34968
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 2805897
Gene end: 2838788
  
Corresponding Affymetrix probe sets: GgaAffx.20220.1.S1_at (Chicken Array)   GgaAffx.3661.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009390
NCBI entrez gene - 428707     See in Manteia.
RefSeq - XM_015278431
RefSeq - NM_001318421
RefSeq - XM_004940650
RefSeq - XM_004940651
RefSeq Peptide - NP_001305350
swissprot - F1N989
Ensembl - ENSGALG00000005853
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 htr2cl1ENSDARG00000018228Danio rerio
 HTR2CENSG00000147246Homo sapiens
 Htr2cENSMUSG00000041380Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HTR2A / Gallus gallus 5-hydroxytryptamine receptor 2A (HTR2A), mRNA. / P28223* / P35363* / 5-hydroxytryptamine receptor 2A* / 5-hydroxytryptamine (serotonin) receptor 2A*ENSGALG0000001699249
HTR2B / 5-hydroxytryptamine receptor 2B / P41595* / Q02152* / 5-hydroxytryptamine (serotonin) receptor 2B*ENSGALG0000000768142
DRD2 / dopamine receptor D2 / P14416* / P61168* / D(2) dopamine receptor *ENSGALG0000000779424
DRD1 / dopamine receptor D1 / P21728* / Q61616* / D(1A) dopamine receptor *ENSGALG0000003969822
HTR6 / 5-hydroxytryptamine receptor 6 / P50406* / Q9R1C8* / 5-hydroxytryptamine (serotonin) receptor 6*ENSGALG0000000406622
DD1CR / dopamine D1C receptor ENSGALG0000000654021
ADRB1 / adrenoceptor beta 1 / P08588* / P34971* / Beta-1 adrenergic receptor *ENSGALG0000000894921
ENSGALG0000001595321
DRD3 / dopamine receptor D3 / P30728* / P35462* / D(3) dopamine receptor *ENSGALG0000001511721
DRD5 / dopamine receptor D5 / P21918* / Q8BLD9* / D(1B) dopamine receptor *ENSGALG0000001497521
DRD4 / dopamine receptor D4 / P21917* / P51436* / D(4) dopamine receptor *ENSGALG0000004076121
ADRB2 / adrenoceptor beta 2 / P07550* / P18762* / Beta-2 adrenergic receptor *ENSGALG0000004003520
ADRB3 / adrenoceptor beta 3 / P13945* / P25962* / Beta-3 adrenergic receptor *ENSGALG0000001901820
HRH2 / histamine receptor H2 / P25021* / P97292* / Histamine H2 receptor *ENSGALG0000002417119


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000377  5-Hydroxytryptamine 2C receptor
 IPR002231  5-hydroxytryptamine receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001662 behavioral fear response IEA
 biological_processGO:0006182 cGMP biosynthetic process IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007208 phospholipase C-activating serotonin receptor signaling pathway IEA
 biological_processGO:0007210 serotonin receptor signaling pathway IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0007631 feeding behavior IEA
 biological_processGO:0010513 positive regulation of phosphatidylinositol biosynthetic process IEA
 biological_processGO:0031644 regulation of neurological system process IEA
 biological_processGO:0032098 regulation of appetite IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043397 regulation of corticotropin-releasing hormone secretion IEA
 biological_processGO:0045600 positive regulation of fat cell differentiation IEA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IEA
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0001587 Gq/11-coupled serotonin receptor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004993 G-protein coupled serotonin receptor activity IBA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0030594 neurotransmitter receptor activity IBA
 molecular_functionGO:0051378 serotonin binding IEA
 molecular_functionGO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding IEA


Pathways (from Reactome)
Pathway description
Serotonin receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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