ENSDARG00000040152


Danio rerio

Features
Gene ID: ENSDARG00000040152
  
Biological name :nek4
  
Synonyms : nek4 / NIMA-related kinase 4
  
Possible biological names infered from orthology : P51957
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 3991911
Gene end: 4024087
  
Corresponding Affymetrix probe sets: Dr.26039.1.A1_at (Zebrafish Array)   NM_201012_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000058727
Ensembl peptide - ENSDARP00000131076
NCBI entrez gene - 393987     See in Manteia.
RefSeq - NM_201012
RefSeq Peptide - NP_957306
swissprot - F1R3Y5
swissprot - A0A0R4IDN6
ZFIN ID - ZDB-GENE-040426-1392
Ensembl - ENSDARG00000040152
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NEK4ENSGALG00000041428Gallus gallus
 NEK4ENSG00000114904Homo sapiens
 Nek4ENSMUSG00000021918Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nek11 / NIMA-related kinase 11 / Q8C0Q4* / Q8NG66* / Serine/threonine-protein kinase Nek11 *ENSDARG0000008756417
nek8 / NIMA-related kinase 8 / Q86SG6* / Q91ZR4* / Serine/threonine-protein kinase Nek8 *ENSDARG0000004562616
NEK3 / NIMA related kinase 3 / P51956*ENSDARG0000005886916
nek12 / NIMA-related kinase 12 / NEK9* / Q8TD19* / Q8K1R7* / NIMA related kinase 9* / Serine/threonine-protein kinase Nek9 *ENSDARG0000003717415
nek2 / NIMA-related kinase 2 / O35942* / P51955* / Serine/threonine-protein kinase Nek2 *ENSDARG0000000561914
nek1 / NIMA-related kinase 1 / P51954* / Q96PY6* / NIMA (never in mitosis gene a)-related expressed kinase 1*ENSDARG0000002235011
nek7 / NIMA-related kinase 7 / Q8TDX7* / Q9ES74* / Serine/threonine-protein kinase Nek7 *ENSDARG0000005696611
nek6 / NIMA-related kinase 6 / Q9ES70* / Q9HC98* / Serine/threonine-protein kinase Nek6 *ENSDARG0000003796310


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IBA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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