ENSDARG00000044550


Danio rerio

Features
Gene ID: ENSDARG00000044550
  
Biological name :hif1al2
  
Synonyms : hif1al2 / hypoxia-inducible factor 1, alpha subunit, like 2
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 27327442
Gene end: 27338639
  
Corresponding Affymetrix probe sets: Dr.25766.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000108595
NCBI entrez gene - 497283     See in Manteia.
RefSeq - NM_001012371
RefSeq Peptide - NP_001012371
swissprot - F1QQQ1
ZFIN ID - ZDB-GENE-050211-2
Ensembl - ENSDARG00000044550
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
epas1a / endothelial PAS domain protein 1a / EPAS1* / Q99814* / P97481* / endothelial PAS domain protein 1* / Endothelial PAS domain-containing protein 1 *ENSDARG0000000869729
hif1ab / hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b / HIF1A* / Q61221* / Q16665* / Hypoxia-inducible factor 1-alpha * / hypoxia inducible fact...ENSDARG0000003429328
hif1aa / hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a / HIF1A* / Q61221* / Q16665* / Hypoxia-inducible factor 1-alpha * / hypoxia inducible fact...ENSDARG0000000618127
epas1b / endothelial PAS domain protein 1b / EPAS1* / Q99814* / P97481* / endothelial PAS domain protein 1* / Endothelial PAS domain-containing protein 1 *ENSDARG0000005767127
hif1al / hypoxia-inducible factor 1, alpha subunit, like / HIF3A* / Q9Y2N7* / Q0VBL6* / Hypoxia-inducible factor 3-alpha * / hypoxia inducible factor 3 alpha subunit*ENSDARG0000010082623
sim1a / single-minded family bHLH transcription factor 1a / SIM1* / Q61045* / P81133* / Single-minded homolog 1 * / single-minded family bHLH transcription factor 1*ENSDARG0000002331619
NPAS3 / neuronal PAS domain protein 3 / Q8IXF0*ENSDARG0000010982018
npas1 / neuronal PAS domain protein 1 / P97459* / Q99742* / Neuronal PAS domain-containing protein 1 *ENSDARG0000001587618
sim1b / single-minded family bHLH transcription factor 1b / SIM1* / Q61045* / P81133* / Single-minded homolog 1 * / single-minded family bHLH transcription factor 1*ENSDARG0000001378917
clocka / clock circadian regulator a / CLOCK* / O15516* / O08785* / clock circadian regulator* / Circadian locomoter output cycles protein kaput *ENSDARG0000001170314
npas2 / neuronal PAS domain protein 2 / Q99743*ENSDARG0000001653614
clockb / clock circadian regulator b / CLOCK* / O15516* / O08785* / clock circadian regulator* / Circadian locomoter output cycles protein kaput *ENSDARG0000000363114
arntl2 / aryl hydrocarbon receptor nuclear translocator-like 2 / Q2VPD4* / Q8WYA1* / Aryl hydrocarbon receptor nuclear translocator-like protein 2 *ENSDARG0000004138113
arntl1a / aryl hydrocarbon receptor nuclear translocator-like 1a / ARNTL* / O00327* / Q9WTL8* / aryl hydrocarbon receptor nuclear translocator like* / Mus musculus aryl hydrocarbon receptor...ENSDARG0000000679113
arntl1b / aryl hydrocarbon receptor nuclear translocator-like 1b / ARNTL* / O00327* / Q9WTL8* / aryl hydrocarbon receptor nuclear translocator like* / Mus musculus aryl hydrocarbon receptor...ENSDARG0000003573213
arnt / aryl hydrocarbon receptor nuclear translocator / P27540* / P53762*ENSDARG0000002185512
arnt2 / aryl-hydrocarbon receptor nuclear translocator 2 / Q61324* / Q9HBZ2*ENSDARG0000010369712
CABZ01064671.1ENSDARG000000399359


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR001610  PAC motif
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR013655  PAS fold-3
 IPR013767  PAS fold
 IPR014887  HIF-1 alpha, transactivation domain, C-terminal
 IPR021537  Hypoxia-inducible factor, alpha subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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