ENSDARG00000103697


Danio rerio

Features
Gene ID: ENSDARG00000103697
  
Biological name :arnt2
  
Synonyms : arnt2 / aryl-hydrocarbon receptor nuclear translocator 2
  
Possible biological names infered from orthology : Q61324 / Q9HBZ2
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 10701732
Gene end: 10877536
  
Corresponding Affymetrix probe sets: Dr.8302.2.S1_a_at (Zebrafish Array)   Dr.8302.3.S1_a_at (Zebrafish Array)   NM_131674_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000131846
Ensembl peptide - ENSDARP00000136894
NCBI entrez gene - 64277     See in Manteia.
RefSeq - NM_131674
RefSeq Peptide - NP_571749
swissprot - A0A0R4ILG9
swissprot - A0A0R4ID51
ZFIN ID - ZDB-GENE-001207-3
Ensembl - ENSDARG00000103697
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARNT2ENSGALG00000006445Gallus gallus
 ARNT2ENSG00000172379Homo sapiens
 Arnt2ENSMUSG00000015709Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arnt / aryl hydrocarbon receptor nuclear translocator / P27540* / P53762*ENSDARG0000002185548
arntl1a / aryl hydrocarbon receptor nuclear translocator-like 1a / ARNTL* / O00327* / Q9WTL8* / aryl hydrocarbon receptor nuclear translocator like* / Mus musculus aryl hydrocarbon receptor...ENSDARG0000000679127
arntl1b / aryl hydrocarbon receptor nuclear translocator-like 1b / ARNTL* / O00327* / Q9WTL8* / aryl hydrocarbon receptor nuclear translocator like* / Mus musculus aryl hydrocarbon receptor...ENSDARG0000003573227
arntl2 / aryl hydrocarbon receptor nuclear translocator-like 2 / Q2VPD4* / Q8WYA1* / Aryl hydrocarbon receptor nuclear translocator-like protein 2 *ENSDARG0000004138126
clocka / clock circadian regulator a / CLOCK* / O15516* / O08785* / clock circadian regulator* / Circadian locomoter output cycles protein kaput *ENSDARG0000001170319
npas2 / neuronal PAS domain protein 2 / Q99743*ENSDARG0000001653618
clockb / clock circadian regulator b / CLOCK* / O15516* / O08785* / clock circadian regulator* / Circadian locomoter output cycles protein kaput *ENSDARG0000000363118
epas1a / endothelial PAS domain protein 1a / EPAS1* / Q99814* / P97481* / endothelial PAS domain protein 1* / Endothelial PAS domain-containing protein 1 *ENSDARG0000000869718
epas1b / endothelial PAS domain protein 1b / EPAS1* / Q99814* / P97481* / endothelial PAS domain protein 1* / Endothelial PAS domain-containing protein 1 *ENSDARG0000005767118
NPAS3 / neuronal PAS domain protein 3 / Q8IXF0*ENSDARG0000010982017
hif1ab / hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b / HIF1A* / Q61221* / Q16665* / Hypoxia-inducible factor 1-alpha * / hypoxia inducible fact...ENSDARG0000003429317
sim1a / single-minded family bHLH transcription factor 1a / SIM1* / Q61045* / P81133* / Single-minded homolog 1 * / single-minded family bHLH transcription factor 1*ENSDARG0000002331616
npas1 / neuronal PAS domain protein 1 / P97459* / Q99742* / Neuronal PAS domain-containing protein 1 *ENSDARG0000001587615
hif1aa / hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a / HIF1A* / Q61221* / Q16665* / Hypoxia-inducible factor 1-alpha * / hypoxia inducible fact...ENSDARG0000000618115
hif1al / hypoxia-inducible factor 1, alpha subunit, like / HIF3A* / Q9Y2N7* / Q0VBL6* / Hypoxia-inducible factor 3-alpha * / hypoxia inducible factor 3 alpha subunit*ENSDARG0000010082615
sim1b / single-minded family bHLH transcription factor 1b / SIM1* / Q61045* / P81133* / Single-minded homolog 1 * / single-minded family bHLH transcription factor 1*ENSDARG0000001378914
hif1al2 / hypoxia-inducible factor 1, alpha subunit, like 2ENSDARG0000004455011
CABZ01064671.1ENSDARG000000399359


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR001067  Nuclear translocator
 IPR001610  PAC motif
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR013655  PAS fold-3
 IPR013767  PAS fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds
Endogenous sterols
Xenobiotics
Aryl hydrocarbon receptor signalling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle increased size , abnormal
cardiac ventricle decreased thickness , abnormal
Show

 ZFA:0000029 hindbrain hindbrain anterior/posterior pattern specification disrupted , abnormal
hindbrain axon morphology , abnormal
hindbrain axon mislocalised , abnormal
hindbrain radial glial cell morphology , abnormal
Show

 ZFA:0000032 hypothalamus hypothalamus dopaminergic neuron decreased amount , abnormal
hypothalamus neurosecretory neuron decreased amount , abnormal
hypothalamus absent , abnormal
Show

 ZFA:0000076 swim bladder swim bladder uninflated , abnormal
Show

 ZFA:0000101 diencephalon diencephalon dopaminergic neuron decreased amount , abnormal
diencephalon ventral region decreased amount , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000470 preoptic area preoptic area neurosecretory neuron decreased amount , abnormal
preoptic area absent , abnormal
Show

 ZFA:0000633 caudal tuberculum caudal tuberculum dopaminergic neuron decreased amount , abnormal
caudal tuberculum neurosecretory neuron decreased amount , abnormal
Show

 ZFA:0000890 floor plate spinal cord region floor plate spinal cord region glial cell (sensu Vertebrata) amount , abnormal
floor plate spinal cord region glial cell (sensu Vertebrata) increased size , abnormal
Show

 ZFA:0001083 ventricular zone ventricular zone neuron projection decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism movement behavioral quality , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head cuboid , abnormal
Show

 ZFA:0001176 blastoderm blastoderm blastoderm cell circular , abnormal
Show

 ZFA:0001261 ventricular system ventricular system increased volume , abnormal
Show

 ZFA:0001659 diencephalic nucleus diencephalic nucleus axon displaced to hindbrain medial region, abnormal
Show

 ZFA:0005091 hepatic sinusoid hepatic sinusoid morphology , abnormal
hepatic sinusoid increased size , abnormal
hepatic sinusoid blood increased volume , abnormal
Show

 ZFA:0007024 anterior neural keel anterior neural keel neuron projection decreased amount , abnormal
Show

 ZFA:0009301 dopaminergic neuron dopaminergic neuron decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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