ENSDARG00000052701


Danio rerio

Features
Gene ID: ENSDARG00000052701
  
Biological name :smpd2b
  
Synonyms : smpd2b / sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase)
  
Possible biological names infered from orthology : O60906 / O70572 / SMPD2 / sphingomyelin phosphodiesterase 2 / sphingomyelin phosphodiesterase 2, neutral
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 54680730
Gene end: 54705050
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000069090
Ensembl peptide - ENSDARP00000154779
NCBI entrez gene - 797914     See in Manteia.
swissprot - E7FBR1
ZFIN ID - ZDB-GENE-130530-640
Ensembl - ENSDARG00000052701
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SMPD2ENSGALG00000033245Gallus gallus
 SMPD2ENSG00000135587Homo sapiens
 Smpd2ENSMUSG00000019822Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
smpd2a / sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase) / SMPD2* / O60906* / sphingomyelin phosphodiesterase 2*ENSDARG0000004052351


Protein motifs (from Interpro)
Interpro ID Name
 IPR005135  Endonuclease/exonuclease/phosphatase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism
TNFR1-mediated ceramide production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018569 tnfrsf1a / tumor necrosis factor receptor superfamily, member 1a / P19438* / P25118* / TNF receptor superfamily member 1A*  / reaction / complex
 ENSDARG00000013598 tnfb / tumor necrosis factor b (TNF superfamily, member 2) / LTA* / TNF* / P01375* / P06804* / P09225* / P01374* / lymphotoxin A* / lymphotoxin alpha* / tumor necrosis factor*  / reaction / complex
 ENSDARG00000051920 nsmaf / neutral sphingomyelinase (N-SMase) activation associated factor / Q92636* / neutral sphingomyelinase activation associated factor*  / reaction / complex
 ENSDARG00000041619 rack1 / O42248 / receptor for activated C kinase 1 / P68040* / P63244* / Receptor of activated protein C kinase 1 Receptor of activated protein C kinase 1, N-terminally processed*  / complex / reaction






 

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