ENSDARG00000052846


Danio rerio

Features
Gene ID: ENSDARG00000052846
  
Biological name :fsta
  
Synonyms : follistatin a / fsta / Q9YHV4
  
Possible biological names infered from orthology : follistatin / follistatin FST315 / FST / P19883
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 40504910
Gene end: 40510399
  
Corresponding Affymetrix probe sets: Dr.198.1.S1_at (Zebrafish Array)   Dr.198.1.S2_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000051064
Ensembl peptide - ENSDARP00000122591
NCBI entrez gene - 100004116     See in Manteia.
RefSeq - NM_131037
RefSeq Peptide - NP_571112
swissprot - Q9YHV4
ZFIN ID - ZDB-GENE-990714-11
Ensembl - ENSDARG00000052846
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FSTENSGALG00000014908Gallus gallus
 FSTENSG00000134363Homo sapiens
 FstENSMUSG00000021765Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fstb / follistatin b / FST* / P19883* / follistatin* / follistatin FST315 *ENSDARG0000005799273
fstl3 / follistatin-like 3 (secreted glycoprotein) / Q9EQC7* / O95633* / follistatin like 3* / Follistatin-related protein 3 *ENSDARG0000002567037


Protein motifs (from Interpro)
Interpro ID Name
 IPR002350  Kazal domain
 IPR003645  Follistatin-like, N-terminal
 IPR015369  Follistatin/Osteonectin EGF domain
 IPR017878  TB domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0009994 oocyte differentiation NAS
 biological_processGO:0030901 midbrain development IMP
 biological_processGO:0043049 otic placode formation IGI
 biological_processGO:0048263 determination of dorsal identity IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 cellular_componentGO:0005576 extracellular region NAS


Pathways (from Reactome)
Pathway description
Antagonism of Activin by Follistatin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000051 otic vesicle otic vesicle aplastic , abnormal
otic vesicle decreased size , abnormal
otic vesicle malformed , abnormal
Show

 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton aplastic , abnormal
Show

 ZFA:0000162 trigeminal placode trigeminal placode decreased size , abnormal
Show

 ZFA:0000217 inner ear inner ear lacks all parts of type otolith , abnormal
Show

 ZFA:0000445 optic tectum optic tectum decreased size , abnormal
optic tectum neuron decreased amount , abnormal
Show

 ZFA:0001216 splanchnocranium splanchnocranium hyperplastic , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage hyperplastic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000103892 CABZ01074203.1 / INHBB* / P09529* / inhibin beta B subunit*  / complex / reaction
 ENSDARG00000012671 inhbaa / inhibin, beta Aa / INHBA* / P08476* / inhibin beta A subunit*  / reaction / complex
 ENSDARG00000040777 inhbb / inhibin, beta B / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*  / complex / reaction
 ENSDARG00000052846 fsta / Q9YHV4 / follistatin a / FST* / P19883* / follistatin* / follistatin FST315 *  / complex / reaction
 ENSDARG00000057992 fstb / follistatin b / FST* / P19883* / follistatin* / follistatin FST315 *  / complex / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr