ENSDARG00000012671


Danio rerio

Features
Gene ID: ENSDARG00000012671
  
Biological name :inhbaa
  
Synonyms : inhbaa / inhibin, beta Aa
  
Possible biological names infered from orthology : INHBA / Inhibin beta A chain / inhibin beta A subunit / P08476 / Q04998
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 3050020
Gene end: 3062610
  
Corresponding Affymetrix probe sets: Dr.16113.1.S1_at (Zebrafish Array)   Dr.26207.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000006400
NCBI entrez gene - 30072     See in Manteia.
swissprot - Q8QGE3
ZFIN ID - ZDB-GENE-000210-21
Ensembl - ENSDARG00000012671
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 INHBAENSGALG00000034616Gallus gallus
 INHBAENSG00000122641Homo sapiens
 InhbaENSMUSG00000041324Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
inhbab / inhibin, beta Ab / INHBA* / P08476* / inhibin beta A subunit*ENSDARG0000002475964
inhbb / inhibin, beta B / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*ENSDARG0000004077742
INHBE / inhibin beta E subunit / INHBC* / P58166* / P55103* / inhibin beta C subunit*ENSDARG0000010098635
CABZ01074203.1 / INHBB* / P09529* / inhibin beta B subunit*ENSDARG0000010389230
tgfb3 / transforming growth factor, beta 3 / P10600*ENSDARG0000001936721
tgfb1a / transforming growth factor, beta 1a / TGFB1* / P01137* / transforming growth factor beta 1*ENSDARG0000004150220
tgfb1b / transforming growth factor, beta 1b / TGFB1* / P04202* / P01137* / transforming growth factor beta 1*ENSDARG0000003489520
gdf11 / growth differentiation factor 11 / O95390* / Q9Z1W4*ENSDARG0000004492420
mstnb / O42222 / myostatin b / MSTN* / O08689* / O14793* / myostatin*ENSDARG0000006913319
mstna / myostatin a / MSTN* / O14793* / O08689* / myostatin*ENSDARG0000004294719
tgfb2 / transforming growth factor, beta 2 / P27090* / P61812* / Transforming growth factor beta-2 Latency-associated peptide*ENSDARG0000002708719
ndr1 / nodal-related 1 / NODAL* / Q96S42* / P43021* / nodal growth differentiation factor*ENSDARG0000005709618
gdf3 / P35621 / growth differentiation factor 3 / GDF1* / CERS1* / Q9NR23* / P27544* / P27545* / Q07104* / P20863* / P27539* / ceramide synthase 1* / growth differentiation factor 1* / Embr...ENSDARG0000003799517
tgfb2l / transforming growth factor, beta 2, likeENSDARG0000007187917
spaw / southpaw / NODAL* / P43021* / Q96S42* / nodal growth differentiation factor*ENSDARG0000001430916
gdf10a / growth differentiation factor 10a / GDF10* / P97737* / P55107* / growth differentiation factor 10*ENSDARG0000009537815
bmp15 / bone morphogenetic protein 15ENSDARG0000003749114
gdf10b / growth differentiation factor 10b / GDF10* / P97737* / P55107* / growth differentiation factor 10*ENSDARG0000007389114
ndr2 / nodal-related 2 / NODAL* / Q96S42* / nodal growth differentiation factor*ENSDARG0000010127914
bmp3 / bone morphogenetic protein 3 / P12645* / Q8BHE5* / Bone morphotic protein 3 *ENSDARG0000006052613


Protein motifs (from Interpro)
Interpro ID Name
 IPR000491  Inhibin, beta A subunit
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0031101 fin regeneration IMP
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0060395 SMAD protein signal transduction IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Signaling by Activin
Glycoprotein hormones
Antagonism of Activin by Follistatin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001269 regenerating fin regenerating fin decreased length , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000104700 acvr2ab / activin A receptor type 2Ab / ACVR2A* / P27037* / activin A receptor type 2A*  / reaction / complex
 ENSDARG00000011188 acvr2aa / activin A receptor type 2Aa / P27038* / ACVR2A* / P27037* / Activin receptor type-2A * / activin A receptor type 2A*  / reaction / complex
 ENSDARG00000044422 acvr2ba / activin A receptor type 2Ba / Q13705* / ACVR2B* / P27040* / Activin receptor type-2B * / activin A receptor type 2B*  / reaction / complex
 ENSDARG00000103108 acvr2bb / activin A receptor type 2Bb / ACVR2B* / Q13705* / activin A receptor type 2B*  / reaction / complex
 ENSDARG00000012671 inhbaa / inhibin, beta Aa / INHBA* / P08476* / inhibin beta A subunit*  / complex
 ENSDARG00000018968 acvr1ba / activin A receptor type 1Ba / Q61271* / ACVR1B* / P36896* / Activin receptor type-1B * / activin A receptor type 1B*  / complex / reaction
 ENSDARG00000052846 fsta / Q9YHV4 / follistatin a / FST* / P19883* / follistatin* / follistatin FST315 *  / reaction / complex
 ENSDARG00000052142 acvr1bb / activin A receptor type 1Bb / Q61271* / ACVR1B* / P36896* / Activin receptor type-1B * / activin A receptor type 1B*  / complex / reaction
 ENSDARG00000052433 inha / inhibin, alpha / P05111* / inhibin alpha subunit*  / complex
 ENSDARG00000040777 inhbb / inhibin, beta B / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*  / complex
 ENSDARG00000057992 fstb / follistatin b / FST* / P19883* / follistatin* / follistatin FST315 *  / reaction / complex
 ENSDARG00000086172 ACVR1C / activin A receptor type 1C / Q8NER5*  / complex
 ENSDARG00000025670 fstl3 / follistatin-like 3 (secreted glycoprotein) / Q9EQC7* / O95633* / follistatin like 3* / Follistatin-related protein 3 *  / reaction / complex
 ENSDARG00000103892 CABZ01074203.1 / INHBB* / P09529* / inhibin beta B subunit*  / complex






 

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