Manteia

ENSDARG00000060526

Danio rerio

Features

Gene ID:	ENSDARG00000060526

Biological name :	bmp3

Synonyms :	bmp3 / bone morphogenetic protein 3

Possible biological names infered from orthology :	Bone morphotic protein 3 / P12645 / Q8BHE5

Species:	Danio rerio

Chr. number:	5
Strand:	1
Band:
Gene start:	39667272
Gene end:	39673477

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000079823 swissprot - A2AVJ4 ZFIN ID - ZDB-GENE-030131-7192 Ensembl - ENSDARG00000060526

See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
BMP3	ENSGALG00000035052	Gallus gallus
BMP3	ENSG00000152785	Homo sapiens
Bmp3	ENSMUSG00000029335	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
gdf10a / growth differentiation factor 10a / GDF10* / P97737* / P55107* / growth differentiation factor 10*	ENSDARG00000095378	39
gdf10b / growth differentiation factor 10b / GDF10* / P97737* / P55107* / growth differentiation factor 10*	ENSDARG00000073891	35
spaw / southpaw / NODAL* / P43021* / Q96S42* / nodal growth differentiation factor*	ENSDARG00000014309	16
gdf3 / P35621 / growth differentiation factor 3 / GDF1* / CERS1* / Q9NR23* / P27544* / P27545* / Q07104* / P20863* / P27539* / ceramide synthase 1* / growth differentiation factor 1* / Embr...	ENSDARG00000037995	16
ndr1 / nodal-related 1 / NODAL* / Q96S42* / P43021* / nodal growth differentiation factor*	ENSDARG00000057096	16
gdf9 / growth differentiation factor 9 / O60383* / Q07105*	ENSDARG00000003229	15
ndr2 / nodal-related 2 / NODAL* / Q96S42* / nodal growth differentiation factor*	ENSDARG00000101279	15
gdf11 / growth differentiation factor 11 / O95390* / Q9Z1W4*	ENSDARG00000044924	14
mstna / myostatin a / MSTN* / O14793* / O08689* / myostatin*	ENSDARG00000042947	14
bmp15 / bone morphogenetic protein 15	ENSDARG00000037491	14
tgfb2 / transforming growth factor, beta 2 / P27090* / P61812* / Transforming growth factor beta-2 Latency-associated peptide*	ENSDARG00000027087	13
inhbb / inhibin, beta B / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*	ENSDARG00000040777	13
INHBE / inhibin beta E subunit / INHBC* / P58166* / P55103* / inhibin beta C subunit*	ENSDARG00000100986	13
tgfb3 / transforming growth factor, beta 3 / P10600*	ENSDARG00000019367	13
tgfb1b / transforming growth factor, beta 1b / TGFB1* / P04202* / P01137* / transforming growth factor beta 1*	ENSDARG00000034895	13
inhbab / inhibin, beta Ab / INHBA* / P08476* / inhibin beta A subunit*	ENSDARG00000024759	13
mstnb / O42222 / myostatin b / MSTN* / O08689* / O14793* / myostatin*	ENSDARG00000069133	13
inhbaa / inhibin, beta Aa / INHBA* / P08476* / inhibin beta A subunit*	ENSDARG00000012671	12
tgfb1a / transforming growth factor, beta 1a / TGFB1* / P01137* / transforming growth factor beta 1*	ENSDARG00000041502	12
tgfb2l / transforming growth factor, beta 2, like	ENSDARG00000071879	12

Protein motifs (from Interpro)

Interpro ID	Name
IPR001839	Transforming growth factor-beta, C-terminal
IPR015615	Transforming growth factor-beta-related
IPR017197	Bone morphogenetic protein 3/3B
IPR017948	Transforming growth factor beta, conserved site
IPR029034	Cystine-knot cytokine

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001649	osteoblast differentiation	IEA
biological_process	GO:0010469	regulation of signaling receptor activity	IEA
biological_process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	IBA
biological_process	GO:0030509	BMP signaling pathway	IBA
biological_process	GO:0042981	regulation of apoptotic process	IBA
biological_process	GO:0043408	regulation of MAPK cascade	IBA
biological_process	GO:0048468	cell development	IBA
biological_process	GO:0048701	embryonic cranial skeleton morphogenesis	IMP
biological_process	GO:0060395	SMAD protein signal transduction	IBA
cellular_component	GO:0005576	extracellular region	IEA
cellular_component	GO:0005615	extracellular space	IBA
molecular_function	GO:0005125	cytokine activity	IEA
molecular_function	GO:0005160	transforming growth factor beta receptor binding	IBA
molecular_function	GO:0008083	growth factor activity	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0001458	cranial cartilage	cranial cartilage hypoplastic , abnormal	Show
ZFA:0001460	pharyngeal arch cartilage	pharyngeal arch cartilage morphology , abnormal	Show
ZFA:0001580	neurocranium	neurocranium morphology , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr