Manteia

ENSDARG00000095378

Danio rerio

Features

Gene ID:	ENSDARG00000095378

Biological name :	gdf10a

Synonyms :	gdf10a / growth differentiation factor 10a

Possible biological names infered from orthology :	GDF10 / growth differentiation factor 10 / P55107 / P97737

Species:	Danio rerio

Chr. number:	13
Strand:	1
Band:
Gene start:	31285660
Gene end:	31289625

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000113675 Ensembl peptide - ENSDARP00000117036 NCBI entrez gene - 563003 See in Manteia. swissprot - B8A5X9 swissprot - F1QRZ6 ZFIN ID - ZDB-GENE-090312-17 Ensembl - ENSDARG00000095378

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
GDF10	ENSGALG00000005985	Gallus gallus
GDF10	ENSG00000266524	Homo sapiens
Gdf10	ENSMUSG00000021943	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
gdf10b / growth differentiation factor 10b / GDF10* / P97737* / P55107* / growth differentiation factor 10*	ENSDARG00000073891	45
bmp3 / bone morphogenetic protein 3 / P12645* / Q8BHE5* / Bone morphotic protein 3 *	ENSDARG00000060526	40
gdf3 / P35621 / growth differentiation factor 3 / GDF1* / CERS1* / Q9NR23* / P27544* / P27545* / Q07104* / P20863* / P27539* / ceramide synthase 1* / growth differentiation factor 1* / Embr...	ENSDARG00000037995	18
ndr1 / nodal-related 1 / NODAL* / Q96S42* / P43021* / nodal growth differentiation factor*	ENSDARG00000057096	16
spaw / southpaw / NODAL* / P43021* / Q96S42* / nodal growth differentiation factor*	ENSDARG00000014309	16
ndr2 / nodal-related 2 / NODAL* / Q96S42* / nodal growth differentiation factor*	ENSDARG00000101279	15
inhbb / inhibin, beta B / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*	ENSDARG00000040777	15
tgfb2l / transforming growth factor, beta 2, like	ENSDARG00000071879	14
mstna / myostatin a / MSTN* / O14793* / O08689* / myostatin*	ENSDARG00000042947	14
inhbaa / inhibin, beta Aa / INHBA* / P08476* / inhibin beta A subunit*	ENSDARG00000012671	14
tgfb1a / transforming growth factor, beta 1a / TGFB1* / P01137* / transforming growth factor beta 1*	ENSDARG00000041502	14
bmp15 / bone morphogenetic protein 15	ENSDARG00000037491	14
tgfb1b / transforming growth factor, beta 1b / TGFB1* / P04202* / P01137* / transforming growth factor beta 1*	ENSDARG00000034895	14
tgfb3 / transforming growth factor, beta 3 / P10600*	ENSDARG00000019367	14
tgfb2 / transforming growth factor, beta 2 / P27090* / P61812* / Transforming growth factor beta-2 Latency-associated peptide*	ENSDARG00000027087	14
inhbab / inhibin, beta Ab / INHBA* / P08476* / inhibin beta A subunit*	ENSDARG00000024759	13
gdf9 / growth differentiation factor 9 / O60383* / Q07105*	ENSDARG00000003229	13
mstnb / O42222 / myostatin b / MSTN* / O08689* / O14793* / myostatin*	ENSDARG00000069133	13
INHBE / inhibin beta E subunit / INHBC* / P58166* / P55103* / inhibin beta C subunit*	ENSDARG00000100986	13
gdf11 / growth differentiation factor 11 / O95390* / Q9Z1W4*	ENSDARG00000044924	13

Protein motifs (from Interpro)

Interpro ID	Name
IPR001839	Transforming growth factor-beta, C-terminal
IPR015615	Transforming growth factor-beta-related
IPR017948	Transforming growth factor beta, conserved site
IPR029034	Cystine-knot cytokine

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0010469	regulation of signaling receptor activity	IEA
biological_process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	IBA
biological_process	GO:0030509	BMP signaling pathway	IBA
biological_process	GO:0042981	regulation of apoptotic process	IBA
biological_process	GO:0043408	regulation of MAPK cascade	IBA
biological_process	GO:0048468	cell development	IBA
biological_process	GO:0060395	SMAD protein signal transduction	IBA
cellular_component	GO:0005576	extracellular region	IEA
cellular_component	GO:0005615	extracellular space	IBA
molecular_function	GO:0005125	cytokine activity	IBA
molecular_function	GO:0005160	transforming growth factor beta receptor binding	IBA
molecular_function	GO:0008083	growth factor activity	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr