ENSGALG00000005985


Gallus gallus

Features
Gene ID: ENSGALG00000005985
  
Biological name :GDF10
  
Synonyms : GDF10 / growth differentiation factor 10
  
Possible biological names infered from orthology : P55107 / P97737
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 18020616
Gene end: 18032111
  
Corresponding Affymetrix probe sets: GgaAffx.3720.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009611
NCBI entrez gene - 423776     See in Manteia.
RefSeq - XM_421648
swissprot - F1NA57
Ensembl - ENSGALG00000005985
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gdf10aENSDARG00000095378Danio rerio
 gdf10bENSDARG00000073891Danio rerio
 GDF10ENSG00000266524Homo sapiens
 Gdf10ENSMUSG00000021943Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BMP3 / bone morphogenetic protein 3 precursor / P12645* / Q8BHE5* / Bone morphotic protein 3 * / bone morphogenetic protein 3*ENSGALG0000003505247
GDF3 / embryonic growth/differentiation factor 1 / GDF1* / CERS1* / P27545* / P27544* / Q9NR23* / Q07104* / P20863* / P27539* / ceramide synthase 1* / growth differentiation factor 3* / gr...ENSGALG0000000316119
BMP15 / bone morphogenetic protein 15 precursor ENSGALG0000000474218
NODAL* / P43021* / Q96S42* / nodal growth differentiation factor*ENSGALG0000000320917
GDF9 / growth differentiation factor 9 / O60383* / Q07105*ENSGALG0000002840716
INHBB / inhibin beta B chain precursor / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*ENSGALG0000002877016
INHBA / inhibin beta A chain precursor / P08476* / Q04998* / Inhibin beta A chain * / inhibin beta A subunit*ENSGALG0000003461615
GDF8 / O42220 / Growth/differentiation factor 8 / MSTN* / O08689* / O14793* / myostatin*ENSGALG0000003945815
TGFB2 / P27090* / P61812* / transforming growth factor beta 2* / Transforming growth factor beta-2 Latency-associated peptide*ENSGALG0000000961214
TGFB3 / transforming growth factor beta 3 / P10600*ENSGALG0000001034614
GDF15* / Q99988* / Q9Z0J7* / growth differentiation factor 15* / Mus musculus growth differentiation factor 15 (Gdf15), transcript variant 2, mRNA.*ENSGALG000000462788


Protein motifs (from Interpro)
Interpro ID Name
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR017197  Bone morphogenetic protein 3/3B
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IEA
 biological_processGO:0030509 BMP signaling pathway IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0045668 negative regulation of osteoblast differentiation IEA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0060395 SMAD protein signal transduction IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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