ENSGALG00000028770


Gallus gallus

Features
Gene ID: ENSGALG00000028770
  
Biological name :INHBB
  
Synonyms : INHBB / inhibin beta B chain precursor
  
Possible biological names infered from orthology : Inhibin beta B chain / inhibin beta B subunit / P09529 / Q04999
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 25714824
Gene end: 25719385
  
Corresponding Affymetrix probe sets: Gga.520.1.S1_at (Chicken Array)   Gga.520.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042014
NCBI entrez gene - 396126     See in Manteia.
RefSeq - NM_205206
RefSeq - XM_015289788
RefSeq Peptide - NP_990537
swissprot - R4GIS0
Ensembl - ENSGALG00000028770
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01074203.1ENSDARG00000103892Danio rerio
 inhbbENSDARG00000040777Danio rerio
 INHBBENSG00000163083Homo sapiens
 InhbbENSMUSG00000037035Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
INHBA / inhibin beta A chain precursor / P08476* / Q04998* / Inhibin beta A chain * / inhibin beta A subunit*ENSGALG0000003461642
GDF8 / O42220 / Growth/differentiation factor 8 / MSTN* / O08689* / O14793* / myostatin*ENSGALG0000003945820
TGFB2 / P27090* / P61812* / transforming growth factor beta 2* / Transforming growth factor beta-2 Latency-associated peptide*ENSGALG0000000961219
TGFB3 / transforming growth factor beta 3 / P10600*ENSGALG0000001034618
GDF3 / embryonic growth/differentiation factor 1 / GDF1* / CERS1* / P27545* / P27544* / Q9NR23* / Q07104* / P20863* / P27539* / ceramide synthase 1* / growth differentiation factor 3* / gr...ENSGALG0000000316118
GDF10 / growth differentiation factor 10 / P55107* / P97737*ENSGALG0000000598516
GDF9 / growth differentiation factor 9 / O60383* / Q07105*ENSGALG0000002840715
NODAL* / P43021* / Q96S42* / nodal growth differentiation factor*ENSGALG0000000320915
BMP3 / bone morphogenetic protein 3 precursor / P12645* / Q8BHE5* / Bone morphotic protein 3 * / bone morphogenetic protein 3*ENSGALG0000003505214
BMP15 / bone morphogenetic protein 15 precursor ENSGALG0000000474214
GDF15* / Q99988* / Q9Z0J7* / growth differentiation factor 15* / Mus musculus growth differentiation factor 15 (Gdf15), transcript variant 2, mRNA.*ENSGALG000000462787


Protein motifs (from Interpro)
Interpro ID Name
 IPR000381  Inhibin, beta B subunit
 IPR001111  TGF-beta, propeptide
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR006311  Twin-arginine translocation pathway, signal sequence
 IPR015615  Transforming growth factor-beta-related
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009267 cellular response to starvation IEA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0032924 activin receptor signaling pathway IEA
 biological_processGO:0044320 cellular response to leptin stimulus IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0046676 negative regulation of insulin secretion IEA
 biological_processGO:0046881 positive regulation of follicle-stimulating hormone secretion IEA
 biological_processGO:0046882 negative regulation of follicle-stimulating hormone secretion IEA
 biological_processGO:0048178 negative regulation of hepatocyte growth factor biosynthetic process IEA
 biological_processGO:0048599 oocyte development IEA
 biological_processGO:0060279 positive regulation of ovulation IEA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Signaling by Activin
Glycoprotein hormones
Antagonism of Activin by Follistatin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006158 ACVR2B / activin receptor type-2B precursor / P27040* / Q13705* / Activin receptor type-2B * / activin A receptor type 2B*  / complex / reaction
 ENSGALG00000028770 INHBB / inhibin beta B chain precursor / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*  / complex
 ENSGALG00000029515 P43031 / Inhibin alpha chain / INHA* / Q04997* / P05111* / inhibin alpha subunit*  / complex
 ENSGALG00000041257 ACVR1C / activin A receptor type 1C / Q8K348* / Q8NER5* / Activin receptor type-1C *  / complex
 ENSGALG00000029599 ACVR1B / activin A receptor type 1B / P36896* / Q61271* / Activin receptor type-1B *  / reaction / complex
 ENSGALG00000012444 ACVR2A / Q90669 / Activin receptor type-2A / P27037* / P27038* / activin A receptor type 2A*  / complex / reaction
 ENSGALG00000034616 INHBA / inhibin beta A chain precursor / P08476* / Q04998* / Inhibin beta A chain * / inhibin beta A subunit*  / complex
 ENSGALG00000042356 FSTL3 / follistatin like 3 / O95633* / Q9EQC7* / Follistatin-related protein 3 *  / complex / reaction






 

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