ENSGALG00000029599


Gallus gallus

Features
Gene ID: ENSGALG00000029599
  
Biological name :ACVR1B
  
Synonyms : activin A receptor type 1B / ACVR1B
  
Possible biological names infered from orthology : Activin receptor type-1B / P36896 / Q61271
  
Species: Gallus gallus
  
Chr. number: 33
Strand: -1
Band:
Gene start: 9635
Gene end: 25890
  
Corresponding Affymetrix probe sets: GgaAffx.9272.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050438
Ensembl peptide - ENSGALP00000056042
NCBI entrez gene - 768878     See in Manteia.
RefSeq - XM_015300266
RefSeq - XM_015300267
swissprot - A0A1D5PT02
Ensembl - ENSGALG00000029599
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acvr1baENSDARG00000018968Danio rerio
 acvr1bbENSDARG00000052142Danio rerio
 ACVR1BENSG00000135503Homo sapiens
 Acvr1bENSMUSG00000000532Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TGFBR1 / transforming growth factor beta receptor 1 / P36897* / Q64729* / transforming growth factor, beta receptor I*ENSGALG0000003317970
ACVR1C / activin A receptor type 1C / Q8K348* / Q8NER5* / Activin receptor type-1C *ENSGALG0000004125762
BMPR1A / bone morphogenetic protein receptor type-1A precursor / P36894* / P36895* / Bone morphotic protein receptor type-1A * / bone morphogenetic protein receptor type 1A*ENSGALG0000000200349
BMPR1B / bone morphogenetic protein receptor type-1B precursor / O00238* / P36898* / bone morphogenetic protein receptor type 1B* / Mus musculus bone morphotic protein receptor, type 1B (B...ENSGALG0000001221649
ACVR1 / Q90ZK6 / Activin receptor type-1 / Q04771* / P37172* / activin A receptor type 1* / Mus musculus activin A receptor, type 1 (Acvr1), transcript variant 5, mRNA.*ENSGALG0000003730147
ACVRL1 / activin A receptor like type 1 / P37023* / Q61288* / Serine/threonine-protein kinase receptor R3 *ENSGALG0000003563545
ACVR2A / Q90669 / Activin receptor type-2A / P27037* / P27038* / activin A receptor type 2A*ENSGALG0000001244428
Q90999 / TGFBR2 / TGF-beta receptor type-2 / Q62312* / P37173* / transforming growth factor beta receptor 2* / transforming growth factor, beta receptor II*ENSGALG0000001144228
ACVR2B / activin receptor type-2B precursor / P27040* / Q13705* / Activin receptor type-2B * / activin A receptor type 2B*ENSGALG0000000615828
ENSGALG0000001205528
BMPR2 / bone morphogenetic protein receptor type 2 / O35607* / Q13873* / Bone morphotic protein receptor type-2 *ENSGALG0000000845926


Protein motifs (from Interpro)
Interpro ID Name
 IPR000333  Ser/Thr protein kinase, TGFB receptor
 IPR000472  Activin types I and II receptor domain
 IPR000719  Protein kinase domain
 IPR003605  GS domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001942 hair follicle development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway IEA
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0032924 activin receptor signaling pathway IEA
 biological_processGO:0032927 positive regulation of activin receptor signaling pathway IEA
 biological_processGO:0038092 nodal signaling pathway IEA
 biological_processGO:0045648 positive regulation of erythrocyte differentiation IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 biological_processGO:1901165 positive regulation of trophoblast cell migration IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 cellular_componentGO:0048179 activin receptor complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004675 transmembrane receptor protein serine/threonine kinase activity IEA
 molecular_functionGO:0004702 obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016361 activin receptor activity, type I IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017002 activin-activated receptor activity IEA
 molecular_functionGO:0019838 growth factor binding IEA
 molecular_functionGO:0034711 inhibin binding IEA
 molecular_functionGO:0046332 SMAD binding IEA
 molecular_functionGO:0048185 activin binding IEA


Pathways (from Reactome)
Pathway description
Signaling by Activin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006158 ACVR2B / activin receptor type-2B precursor / P27040* / Q13705* / Activin receptor type-2B * / activin A receptor type 2B*  / reaction / complex
 ENSGALG00000012444 ACVR2A / Q90669 / Activin receptor type-2A / P27037* / P27038* / activin A receptor type 2A*  / reaction / complex
 ENSGALG00000028770 INHBB / inhibin beta B chain precursor / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*  / reaction / complex
 ENSGALG00000029599 ACVR1B / activin A receptor type 1B / P36896* / Q61271* / Activin receptor type-1B *  / complex / reaction
 ENSGALG00000014184 SMAD2* / Q15796* / Q62432* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / reaction
 ENSGALG00000034616 INHBA / inhibin beta A chain precursor / P08476* / Q04998* / Inhibin beta A chain * / inhibin beta A subunit*  / complex / reaction
 ENSGALG00000036001 SMAD2Z / SMAD2* / Q62432* / Q15796* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / reaction






 

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