ENSMUSG00000000532


Mus musculus

Features
Gene ID: ENSMUSG00000000532
  
Biological name :Acvr1b
  
Synonyms : Activin receptor type-1B / Acvr1b / Q61271
  
Possible biological names infered from orthology : activin A receptor type 1B / P36896
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: F1
Gene start: 101174067
Gene end: 101213684
  
Corresponding Affymetrix probe sets: 10427015 (MoGene1.0st)   1422098_at (Mouse Genome 430 2.0 Array)   1433725_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000000544
NCBI entrez gene - 11479     See in Manteia.
MGI - MGI:1338944
RefSeq - NM_007395
RefSeq Peptide - NP_031421
swissprot - Q3TZF1
swissprot - Q61271
Ensembl - ENSMUSG00000000532
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acvr1baENSDARG00000018968Danio rerio
 acvr1bbENSDARG00000052142Danio rerio
 ACVR1BENSGALG00000029599Gallus gallus
 ACVR1BENSG00000135503Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q64729 / Tgfbr1 / transforming growth factor, beta receptor I / P36897* / transforming growth factor beta receptor 1*ENSMUSG0000000761369
Acvr1c / Q8K348 / Activin receptor type-1C / Q8NER5* / activin A receptor type 1C*ENSMUSG0000002683463
Bmpr1b / P36898 / Mus musculus bone morphotic protein receptor, type 1B (Bmpr1b), transcript variant 6, mRNA. / O00238* / bone morphogenetic protein receptor type 1B*ENSMUSG0000005243049
Bmpr1a / P36895 / Bone morphotic protein receptor type-1A / P36894* / bone morphogenetic protein receptor type 1A*ENSMUSG0000002179649
Acvr1 / P37172 / Mus musculus activin A receptor, type 1 (Acvr1), transcript variant 5, mRNA. / Q04771* / activin A receptor type 1*ENSMUSG0000002683648
Acvrl1 / Q61288 / Serine/threonine-protein kinase receptor R3 / P37023* / activin A receptor like type 1*ENSMUSG0000000053047
Q62312 / Tgfbr2 / transforming growth factor, beta receptor II / P37173* / transforming growth factor beta receptor 2*ENSMUSG0000003244029
Acvr2a / P27038 / Activin receptor type-2A / P27037* / activin A receptor type 2A*ENSMUSG0000005215528
Acvr2b / P27040 / Activin receptor type-2B / Q13705* / activin A receptor type 2B*ENSMUSG0000006139328
Bmpr2 / O35607 / Bone morphotic protein receptor type-2 / Q13873* / bone morphogenetic protein receptor type 2*ENSMUSG0000006733626
Amhr2 / Q8K592 / Mus musculus anti-Mullerian hormone type 2 receptor (Amhr2), transcript variant 2, mRNA. / Q16671* / anti-Mullerian hormone receptor type 2*ENSMUSG0000002304726


Protein motifs (from Interpro)
Interpro ID Name
 IPR000333  Ser/Thr protein kinase, TGFB receptor
 IPR000472  Activin types I and II receptor domain
 IPR000719  Protein kinase domain
 IPR003605  GS domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IEA
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001942 hair follicle development IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway IEA
 biological_processGO:0007417 central nervous system development IEA
 biological_processGO:0007498 mesoderm development ISO
 biological_processGO:0009966 regulation of signal transduction IDA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0032924 activin receptor signaling pathway IEA
 biological_processGO:0032927 positive regulation of activin receptor signaling pathway IEA
 biological_processGO:0038092 nodal signaling pathway IEA
 biological_processGO:0045648 positive regulation of erythrocyte differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046545 development of primary female sexual characteristics IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 biological_processGO:1901165 positive regulation of trophoblast cell migration IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 cellular_componentGO:0048179 activin receptor complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0004675 transmembrane receptor protein serine/threonine kinase activity TAS
 molecular_functionGO:0004702 obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016361 activin receptor activity, type I IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017002 activin-activated receptor activity IEA
 molecular_functionGO:0019838 growth factor binding IEA
 molecular_functionGO:0034711 inhibin binding ISO
 molecular_functionGO:0046332 SMAD binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048185 activin binding IEA


Pathways (from Reactome)
Pathway description
Signaling by Activin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000367 abnormal coat/ hair morphology "anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0000377 abnormal hair follicle "malformed invagination of the epidermis from which the hair shaft develops" [J:65031]
Show

Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0000414 alopecia "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

Allelic Composition: Acvr1btm1.1Gsu/Acvr1btm1.1Gsu,Tg(KRT14-cre)8Brn/Tg(KRT14-cre)8Brn
Genetic Background: involves: 129 * C57BL/6J * FVB

 MP:0000427 abnormal hair cycle "aberrant growth or asynchronous timing of the hair growth " [J:65302]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0000652 enlarged sebaceous gland "increased size of the sebum secreting glands of the hair shaft" [J:30249]
Show

Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0000783 abnormal forebrain morphology "malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Acvr1ctm1Cfi/Acvr1c+,Gdf1tm1Sjl/Gdf1+,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129 * C57BL/6

 MP:0001102 small superior vagus ganglion "reduced size of the upper ganglion of the vagus nerve located at the jugular foramen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]
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Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
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Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0001216 abnormal epidermal layer morphology "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0001219 thickened epidermis "increase in the width of the epidermal cell layer in the skin" [J:65146]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0001566 hyperphosphatemia "abnormally high concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0001683 absent mesoderm "missing or failure to differentiate the middle primary germ layer " [J:40594]
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Allelic Composition: Unc13atm1Bros/Unc13atm1Bros
Genetic Background: Not Specified

 MP:0001693 failure of primitive streak formation "inability to form the epiblast ridge from which arises the germ layers of the embryo" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:33880]
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Allelic Composition: Unc13atm1Bros/Unc13atm1Bros
Genetic Background: Not Specified

 MP:0001694 failure to form egg cylinders "inability of inner cell mass cells to grow towards the abembryonic pole to form a cylinder-like structure" [The Atlas of Mouse Development , Revised edition:ISBN 0-12-402035-6, MGI:cls, J:34458]
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Allelic Composition: Unc13atm1Bros/Unc13atm1Bros
Genetic Background: Not Specified

 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
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Allelic Composition: Unc13atm1Bros/Unc13atm1Bros
Genetic Background: Not Specified

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

Allelic Composition: Acvr1btm1.1Gsu/Acvr1btm1.1Gsu,Tg(KRT14-cre)8Brn/Tg(KRT14-cre)8Brn
Genetic Background: involves: 129 * C57BL/6J * FVB

 MP:0002073 abnormal hair growth "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Casp8tm1.1Raz/Casp8tm1.1Raz
Genetic Background: involves: 129P2/OlaHsd

 MP:0002230 abnormal primitive streak formation "anomaly in the establishment of the midline ridge of embryonic epiblast that later develops into mesoderm and endoderm" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Acvr1ctm1Cfi/Acvr1c+,Gdf1tm1Sjl/Gdf1+,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129 * C57BL/6

 MP:0002239 abnormal nasal septum morphology "any structural anomaly of the structure that separates the two nasal cavities " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Acvr1ctm1Cfi/Acvr1c+,Gdf1tm1Sjl/Gdf1+,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129 * C57BL/6

 MP:0002582 disorganized extraembryonic tissue "a lack of the regular arrangement of the membranes involved with the embryo s protection and nutrition" [J:40596, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Unc13atm1Bros/Unc13atm1Bros
Genetic Background: Not Specified

 MP:0002768 small adrenal glands "reduced size of endocrine glands located above the kidneys responsible for hormone and epinephrine secretion" [J:78062]
Show

Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0003414 epidermal cyst "a cyst formed of a mass of epidermal cells which is present beneath the epidermis; the wall is lined with stratified squamous epithelium and exhibits increased/abnormal keratinization" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0003815 nude "having no hair at some time during or throughout lifespan, generally referring to primary genetic hairlessness" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0003875 abnormal hair follicle regresssion "abnormal length of time for the onset of catagen phase of the cyclic trasnformation of the hair follicle " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0003886 abnormal embryonic epiblast morphology "anomaly in the development/organization of the tissue that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Unc13atm1Bros/Unc13atm1Bros
Genetic Background: Not Specified

 MP:0005076 abnormal cell differentiation "anomaly in the process whereby relatively unspecialized cells, e. g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism s life history" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Unc13atm1Bros/Unc13atm1Bros
Genetic Background: Not Specified

 MP:0005157 holoprosencephaly "presence of a single forebrain hemisphere or lobe; often accompanied by a deficit in median facial development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83058]
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Allelic Composition: Acvr1btm1Enl/Acvr1b+,Gdf1tm1Sjl/Gdf1tm1Sjl
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0005501 abnormal skin physiology "atypical function of the membranous protective covering of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0009535 abnormal skin sebaceous gland morphology "any structural anomaly of the holocrine glands of the dermis that secrete sebum into the hair follicles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0009715 thick epidermis stratum basale "increased thickness of the deepest layer of the epidermis, which is composed of dividing stem cells and anchoring cells" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0010096 abnormal incisor color "anomaly in the color and shading of the incisor, which normally presents in shades of white" [PMID:12407097]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0010126 abnormal distal visceral endoderm morphology "any structural anomaly of the precursors of the anterior visceral endoderm that arises at the distal tip of the embryo" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:17387317]
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Allelic Composition: Unc13atm1Bros/Unc13atm1Bros
Genetic Background: Not Specified

 MP:0010680 abnormal skin adnexa physiology "any functional anomaly of the tissue or structures associated with or embedded in the skin such as hair and hair follicles, sweat glands, sebaceous glands and claws or nails" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0010699 dilated hair follicles "the luminal space of the hair follicle is increased in volume or area, sometimes with an increase of contained fluid or sebum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

 MP:0010736 abnormal extraembryonic ectoderm morphology "any structural anomaly of the layer of the ectoderm of the extraembryonic tissue" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Unc13atm1Bros/Unc13atm1Bros
Genetic Background: Not Specified

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Col2a1Lpk/Col2a1Lpk
Genetic Background: involves: C3H/HeH * C57BL/6J

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Unc13atm1Bros/Unc13atm1Bros
Genetic Background: Not Specified

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0011186 abnormal visceral endoderm morphology "any structural anomaly of the primitive endoderm-derived tissue which remains in contact with and surrounds the extra-embryonic ectoderm and the epiblast and provides signals for the differentiation and patterning of the epiblast; a small number of visceral endoderm cells also contribute to the endoderm of the embryonic gut" [PMID:21123814]
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Allelic Composition: Unc13atm1Bros/Unc13atm1Bros
Genetic Background: Not Specified

 MP:0012157 rostral body truncation "rostral part of body truncated; typically with the caudal portion of the body relatively normal" [MGI:csmith]
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Allelic Composition: Acvr1btm1Enl/Acvr1b+,Gdf1tm1Sjl/Gdf1tm1Sjl
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
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Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
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Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0030136 abnormal lower incisor morphology "any structural anomaly of the lower set of long teeth that are the most anterior and prominent in the jaw" [MGI:anna]
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Allelic Composition: Leprdb-lb/Leprdb-lb
Genetic Background: C57BL/6NCrl-Leprdb-lb/Crl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000109523 Gdf1 / P20863 / Embryonic growth/differentiation factor 1 / CERS1* / P27544* / P27539* / ceramide synthase 1* / growth differentiation factor 1*  / complex / reaction
 ENSMUSG00000024563 Smad2 / Q62432 / Mothers against decapentaplegic homolog 2 / Q15796* / SMAD family member 2*  / reaction
 ENSMUSG00000052155 Acvr2a / P27038 / Activin receptor type-2A / P27037* / activin A receptor type 2A*  / complex / reaction
 ENSMUSG00000000532 Acvr1b / Q61271 / Activin receptor type-1B / P36896* / activin A receptor type 1B*  / complex / reaction
 ENSMUSG00000032402 Smad3 / Q8BUN5 / Mothers against decapentaplegic homolog 3 / P84022* / SMAD family member 3*  / reaction
 ENSMUSG00000061393 Acvr2b / P27040 / Activin receptor type-2B / Q13705* / activin A receptor type 2B*  / complex / reaction
 ENSMUSG00000037171 Nodal / P43021 / Q96S42* / nodal growth differentiation factor*  / complex / reaction
 ENSMUSG00000026124 Cfc1 / P97766 / Cryptic protein / CFC1B* / P0CG36* / P0CG37* / cripto, FRL-1, cryptic family 1* / cripto, FRL-1, cryptic family 1B*  / complex
 ENSMUSG00000037035 Inhbb / Q04999 / Inhibin beta B chain / P09529* / inhibin beta B subunit*  / complex / reaction
 ENSMUSG00000041324 Inhba / Q04998 / Inhibin beta A chain / P08476* / inhibin beta A subunit*  / reaction / complex






 

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