Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000208	decreased hematocrit	"less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
MP:0000240	extramedullary hematopoiesis	"formation and development of blood cells outside the bone marrow, e.g., in the spleen, liver, or lymph nodes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
MP:0000242	impaired fertilization	"defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv
MP:0000527	abnormal kidney development	"anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Wnt4^tm1.1Boer/Wnt4^tm1.2Boer Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
MP:0001120	abnormal uterus morphology	"malformation or absence of the female muscular organ of gestation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dicer1^tm1Bdh/Dicer1^tm1Bdh,Plekha5^{Tg(AMH-cre)1Flor}/0 Genetic Background: involves: 129/Sv * C57BL/6 * SJL
MP:0001123	dilated uterus	"stretched or enlarged female muscular organ of gestation" [J:50844]	Show Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr,Inha^tm1Bay/Inha^tm1Bay Genetic Background: involves: 129S7/SvEvBrd
MP:0001126	abnormal ovary morphology	"malformed female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv
MP:0001129	impaired ovarian folliculogenesis	"a block in the formation of the spherical ovum in the ovary" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv
MP:0001130	abnormal ovarian folliculogenesis	"atypical formation or failure to form the spherical ovum in the ovary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:35782]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad4^tm1Rob/Smad4^tm1.1Rob Genetic Background: involves: 129S/SvEv * C57BL/6J
MP:0001131	abnormal ovarian follicles	"malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042]	Show Allelic Composition: Mbd2^tm1Bh/Mbd2^tm1Bh,Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Inhba^tm1Zuk/Inhba^tm3Zuk,Inhbb^tm1Jae/Inhbb^tm1Jae,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad2^tm1Cxd/Smad2^tm1.1Mwst,Smad3^tm1Par/Smad3^tm1Zuk Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Foxo1^tm1Rdp/Foxo1^tm1.1Rdp,Foxo3^tm1Rdp/Foxo3^tm1.1Rdp,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
MP:0001134	absent corpora lutea	"missing yellow endocrine body formed in the ovary after follicle rupture" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0001146	abnormal testis morphology	"anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Tcrb^tm1Mom/Tcrb^tm1Mom,Tcrd^tm1Mom/Tcrd^tm1Mom,Traf3ip2^tm1.1Lix/Traf3ip2^tm1.1Lix Genetic Background: B6.129-Tcrb^tm1Mom Traf3ip2^tm1.1Lix Tcrd^tm1Mom Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc1^tm1Djk/Tsc1^tm1Djk Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc2^tm1.1Mjg/Tsc2^tm1.1Mjg Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0001147	small testis	"reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ar^tm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Stk11^tm1Rdp/Stk11^tm1Rdp Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc1^tm1Djk/Tsc1^tm1Djk Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc2^tm1.1Mjg/Tsc2^tm1.1Mjg Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0001152	Leydig cell hyperplasia	"increased number of interstitial cells of the seminiferous tubules that secrete testosterone" [J:45065]	Show Allelic Composition: Raf1^tm1Bacc/Raf1^tm1Bacc Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: involves: 129S7/SvEvBrd
MP:0001153	small seminiferous tubules	"reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ar^tm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0001154	seminiferous tubule degeneration	"a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]	Show Allelic Composition: Raf1^tm1Bacc/Raf1^tm1Bacc Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺ Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 Allelic Composition: Ctnnb1^tm1Mmt/Ctnnb1⁺,Kras^tm4Tyj/Kras⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0001155	arrest of spermatogenesis	"block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ar^tm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0001156	abnormal spermatogenesis	"incomplete maturation or aberrant formation of the male gametes" [J:58959]	Show Allelic Composition: Tcrb^tm1Mom/Tcrb^tm1Mom,Tcrd^tm1Mom/Tcrd^tm1Mom,Traf3ip2^tm1.1Lix/Traf3ip2^tm1.1Lix Genetic Background: B6.129-Tcrb^tm1Mom Traf3ip2^tm1.1Lix Tcrd^tm1Mom Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc1^tm1Djk/Tsc1^tm1Djk Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc2^tm1.1Mjg/Tsc2^tm1.1Mjg Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0001272	increased metastatic potential		Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ Allelic Composition: Pten^tm1Hwu/Pten^tm1Hwu,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Dicer1^tm1Tara/Dicer1^tm1Tara,Pten^tm1Hwu/Pten^tm1Hwu,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Dicer1^tm1Tara/Dicer1^tm1Tara,Pten^tm1Hwu/Pten^tm1Hwu,Trp53^tm2Tyj/Trp53⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Pten^tm1Hwu/Pten^tm1Hwu,Trp53^tm2Tyj/Trp53⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd
MP:0001511	disheveled coat	"coat that looks generally unkempt" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Wnt4^tm1.1Boer/Wnt4^tm1.2Boer Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
MP:0001577	anemia	"less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
MP:0001712	abnormal placental development	"malformed or incomplete differentiation of the organ of metabolic exchange between the fetus and mother" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0001716	abnormal placental labyrinth	"malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0001728	failure of implantation	"inability of the blastocyst to attach to the endometrium of the uterus" [J:38772]	Show Allelic Composition: Dicer1^tm1Bdh/Dicer1^tm1Bdh,Plekha5^{Tg(AMH-cre)1Flor}/0 Genetic Background: involves: 129/Sv * C57BL/6 * SJL
MP:0001729	impaired implantation	"impaired ability of the blastocyst to attach to the endometrium of the uterus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0001732	postnatal growth retardation	"slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Wnt4^tm1.1Boer/Wnt4^tm1.2Boer Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
MP:0001749	suppressed circulating follicle stimulating hormone level	"repression of secretion into the blood of FSH, the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [J:45065, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Prdm16^csp1/Prdm16^csp1 Genetic Background: involves: BALB/c * C57BL/6J * FVB/NJ Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2.1Rob,Smad5^tm1Huy/Smad5^tm1Huy Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J Allelic Composition: Foxo1^tm1Rdp/Foxo1^tm1.1Rdp,Foxo3^tm1Rdp/Foxo3^tm1.1Rdp,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
MP:0001750	increased circulating follicle stimulating hormone level	"higher than normal levels in the blood stream of FSH, the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [J:35782, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad2^tm1Cxd/Smad2^tm1.1Mwst,Smad3^tm1Par/Smad3^tm1Zuk Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Kmt2b^tm1Afst/Kmt2b^tm1.1Afst,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
MP:0001751	increased circulating luteinizing hormone level	"higher than the normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35782, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad2^tm1Cxd/Smad2^tm1.1Mwst,Smad3^tm1Par/Smad3^tm1Zuk Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0001785	edema	"an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065]	Show Allelic Composition: Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0001914	hemorrhage	"loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0001922	reduced male fertility	"reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]	Show Allelic Composition: Raf1^tm1Bacc/Raf1^tm1Bacc Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: involves: 129S7/SvEvBrd
MP:0001923	reduced female fertility	"reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Inhba^tm1Zuk/Inhba^tm3Zuk Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad2^tm1Cxd/Smad2^tm1.1Mwst,Smad3^tm1Par/Smad3^tm1Zuk Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Kmt2b^tm1Afst/Kmt2b^tm1.1Afst,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0001924	infertility	"inability to produce live offspring" [J:47225]	Show Allelic Composition: Mbd2^tm1Bh/Mbd2^tm1Bh,Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001925	male infertility	"inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Raf1^tm1Bacc/Raf1^tm1Bacc Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amh^tm1Bhr/Amh^tm1Bhr,Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: Not Specified Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2.1Rob,Smad5^tm1Huy/Smad5^tm1Huy Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ar^tm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺ Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0001926	female infertility	"inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv Allelic Composition: Inhba^tm1Zuk/Inhba^tm3Zuk,Inhbb^tm1Jae/Inhbb^tm1Jae,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0001928	abnormal ovulation	"aberration in the release of an ovum from a rupturing Graafin follicle, normally regulated by a surge in lutenizing hormone" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0001930	abnormal meiosis	"malfunction in the process of nuclear division that results in gametes with one half the normal number of the original cell" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ar^tm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0001935	reduced litter size	"fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad4^tm1Rob/Smad4^tm1.1Rob Genetic Background: involves: 129S/SvEv * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Inhba^tm1Zuk/Inhba^tm3Zuk Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad2^tm1Cxd/Smad2^tm1.1Mwst,Smad3^tm1Par/Smad3^tm1Zuk Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Wnt4^tm1.1Boer/Wnt4^tm1.2Boer Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ Allelic Composition: Pten^tm1Hwu/Pten^tm1Hwu,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0001939	secondary sex reversal	"secondary sexual phenotype is not consistent with the chromosomal sex, i.e., internal and/or external genitalia are inconsistent with chromosomal sex " [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Raf1^tm1Bacc/Raf1^tm1Bacc Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amh^tm1Bhr/Amh^tm1Bhr,Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: Not Specified Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr,Inha^tm1Bay/Inha^tm1Bay Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr,Inha^tm1Bay/Inha⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amh^tm1Bhr/Amh⁺,Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Bmpr1a^tm1Bhr/Bmpr1a^tm2.1Bhr Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2^tm3(cre)Bhr Genetic Background: involves: 129S7/SvEvBrd
MP:0001940	testicular hypoplasia	"decreased cell number in the testicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0002016	ovarian cysts	"cystic ovary; usually refers to a benign growth" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv Allelic Composition: Inhba^tm1Zuk/Inhba^tm3Zuk,Inhbb^tm1Jae/Inhbb^tm1Jae,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Foxo1^tm1Rdp/Foxo1^tm1.1Rdp,Foxo3^tm1Rdp/Foxo3^tm1.1Rdp,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
MP:0002020	increased tumor incidence	"greater than average number of tumors, usually a specific type" [MGI:cls, J:34193]	Show Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr,Inha^tm1Bay/Inha^tm1Bay Genetic Background: involves: 129S7/SvEvBrd
MP:0002038	carcinoma	"malignant neoplasm arising from epithelial cells, usually glandular or squamous" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]	Show Allelic Composition: Dicer1^tm1Tara/Dicer1^tm1Tara,Pten^tm1Hwu/Pten^tm1Hwu,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Dicer1^tm1Tara/Dicer1^tm1Tara,Pten^tm1Hwu/Pten^tm1Hwu,Trp53^tm2Tyj/Trp53⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Prdm16^csp1/Prdm16^csp1 Genetic Background: involves: BALB/c * C57BL/6J * FVB/NJ Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2.1Rob,Smad5^tm1Huy/Smad5^tm1Huy Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Wnt4^tm1.1Boer/Wnt4^tm1.2Boer Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ Allelic Composition: Dicer1^tm1Tara/Dicer1^tm1Tara,Pten^tm1Hwu/Pten^tm1Hwu,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Dicer1^tm1Tara/Dicer1^tm1Tara,Pten^tm1Hwu/Pten^tm1Hwu,Trp53^tm2Tyj/Trp53⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Pten^tm1Hwu/Pten^tm1Hwu,Trp53^tm2Tyj/Trp53⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd
MP:0002210	abnormal sex determination	"anomaly of primary or secondary sexual development or characteristics" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Wnt4^tm1.2Bhr/Wnt4^tm1.2Bhr Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J
MP:0002216	abnormal seminiferous tubule morphology	"malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ar^tm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Stk11^tm1Rdp/Stk11^tm1Rdp Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc1^tm1Djk/Tsc1^tm1Djk Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc2^tm1.1Mjg/Tsc2^tm1.1Mjg Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0002286	cryptorchism	"failure of one or both of the testes to descend into the scrotum around the time of birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0002295	abnormal pulmonary circulation	"anomalous circulation of blood through the lungs" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
MP:0002637	small uterus	"reduced size of the female muscular organ of gestation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129
MP:0002676	uterine hyperplasia	"increased size of the uterus due to increased cell number" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0002680	decreased number of corpora lutea	"fewer than normal numbers of yellow endocrine body formed in the ovary after follicle rupture in a given oestrus cycle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv
MP:0002681	increased number of corpora lutea	"greater than normal numbers of yellow endocrine body formed in the ovary after follicle rupture in a given oestrus cycle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Inhba^tm1Zuk/Inhba^tm3Zuk Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J Allelic Composition: Inhba^tm1Zuk/Inhba^tm3Zuk,Inhbb^tm1Jae/Inhbb^tm1Jae,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
MP:0002682	reduced number of mature ovarian follicles	"fewer than normal numbers of spehroidal cell aggregations in the ovary containing the ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad4^tm1Rob/Smad4^tm1.1Rob Genetic Background: involves: 129S/SvEv * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Wnt4^tm1.1Boer/Wnt4^tm1.2Boer Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
MP:0002768	small adrenal glands	"reduced size of endocrine glands located above the kidneys responsible for hormone and epinephrine secretion" [J:78062]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0002773	decreased circulating luteinizing hormone level	"lower than normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35132, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Foxo1^tm1Rdp/Foxo1^tm1.1Rdp,Foxo3^tm1Rdp/Foxo3^tm1.1Rdp,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
MP:0002780	decreased circulating testosterone level	"less than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ar^tm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0002784	abnormal Sertoli cell morphology	"malformation of the cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [J:65900, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Raf1^tm1Bacc/Raf1^tm1Bacc Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Stk11^tm1Rdp/Stk11^tm1Rdp Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc1^tm1Djk/Tsc1^tm1Djk Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc2^tm1.1Mjg/Tsc2^tm1.1Mjg Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0002789	male pseudohermaphroditism	"pseudohermaphroditism in which the gonads are male (testes) and the karyotype is XY but the secondary sex characteristics are female-like or ambiguous" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Raf1^tm1Bacc/Raf1^tm1Bacc Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amh^tm1Bhr/Amh^tm1Bhr,Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: Not Specified Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr,Inha^tm1Bay/Inha^tm1Bay Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr,Inha^tm1Bay/Inha⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amh^tm1Bhr/Amh⁺,Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Bmpr1a^tm1Bhr/Bmpr1a^tm2.1Bhr Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2^tm3(cre)Bhr Genetic Background: involves: 129S7/SvEvBrd
MP:0003205	testicular atrophy	"wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺ Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0003231	abnormal placental vasculature	"malformation in the vessels of the placenta" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93157]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0003355	reduced ovulation	"reduction in the frequency in which an ovum is released from a rupturing ovarian follicle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad4^tm1Rob/Smad4^tm1.1Rob Genetic Background: involves: 129S/SvEv * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129
MP:0003379	absent sexual maturation	"failure to initiate pubertal changes that result in achievement of full sexual capacity" [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0003403	absent placental labyrinth	"malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:73417]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0003574	abnormal oviduct morphology	"malformation of the tube through which the ova pass from the ovary to the uterus" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129 Allelic Composition: Dicer1^tm1Tara/Dicer1^tm1Tara,Pten^tm1Hwu/Pten^tm1Hwu,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd
MP:0003579	ovarian carcinoma		Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2.1Rob,Smad5^tm1Huy/Smad5^tm1Huy Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk,Smad9^tm1Jfm/Smad9^tm1Jfm Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 Allelic Composition: Dicer1^tm1Tara/Dicer1^tm1Tara,Pten^tm1Hwu/Pten^tm1Hwu,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Dicer1^tm1Tara/Dicer1^tm1Tara,Pten^tm1Hwu/Pten^tm1Hwu,Trp53^tm2Tyj/Trp53⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Pten^tm1Hwu/Pten^tm1Hwu,Trp53^tm2Tyj/Trp53⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd
MP:0003582	abnormal ovary development	"abnormal morphogenesis of the female reproductive gland containing the germ cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Wnt4^tm1.1Boer/Wnt4^tm1.2Boer Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
MP:0003700	abnormal oviduct transport	"increased or decreased rate of passage of embryos or oocytes from the ovary to the uterus" [J:97633, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129
MP:0003826	abnormal Mullerian duct morphology	"malformation of the transient embryonic tubes that empty into the cloaca and in the female develop into the oviducts, uterus, and vagina" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Wnt4^tm1.2Bhr/Wnt4^tm1.2Bhr Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J
MP:0003830	abnormal testis development	"abnormal morphogenesis of the male reproductive gland containing the germ cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:100020]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0004014	abnormal uterine environment	"anomaly or inability of the uterus to support embryonic development" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0004244	abnormal spontaneous abortion rate	"change in frequency of a natural or accidental termination of a pregnancy at a stage where the embryo or the fetus is incapable of surviving independently of the mother" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0004256	abnormal maternal decidual layer morphology	"anomaly in the structure of the maternal uterine-derived portion of the placenta" [PMID:11433360]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0004505	decreased renal glomerulus number	"reduced number of the capillary loops of the kidney that normally function as a filtration unit" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Wnt4^tm1.1Boer/Wnt4^tm1.2Boer Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
MP:0004805	absent oocytes	"absence of mature germ cells in the female" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Inhba^tm1Zuk/Inhba^tm3Zuk,Inhbb^tm1Jae/Inhbb^tm1Jae,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
MP:0004834	ovary hemorrhage	"presence of bleeding in the ovary" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pgf^tm1Pec/Pgf^tm1Pec Genetic Background: involves: 129/Sv Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0004852	decreased testis weight	"reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Stk11^tm1Rdp/Stk11^tm1Rdp Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc1^tm1Djk/Tsc1^tm1Djk Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc2^tm1.1Mjg/Tsc2^tm1.1Mjg Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0004855	increased ovary weight	"greater average weight of the female reproductive gland containing the germ cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Inhba^tm1Zuk/Inhba^tm3Zuk,Inhbb^tm1Jae/Inhbb^tm1Jae,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
MP:0004856	decreased ovary weight	"reduction in the average weight of the female reproductive gland containing the germ cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Wnt4^tm1.1Boer/Wnt4^tm1.2Boer Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
MP:0004896	abnormal endometrium morphology	"any structural anomaly of the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy" [MESH:A05.360.319.679.490, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0004901	decreased male germ cell number	"reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Stk11^tm1Rdp/Stk11^tm1Rdp Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc1^tm1Djk/Tsc1^tm1Djk Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc2^tm1.1Mjg/Tsc2^tm1.1Mjg Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0004905	decreased uterus weight	"reduction in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129
MP:0005031	abnormal trophoblast	"malformation of the mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and contributes to the formation of the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0005131	increased follicle stimulating hormone level	"greater than expected concentration of the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Inhba^tm1Zuk/Inhba^tm3Zuk,Inhbb^tm1Jae/Inhbb^tm1Jae,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
MP:0005158	ovary hypoplasia	"underdeveloped ovaries, usually due to reduced cell number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:78931]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0005159	azoospermia	"absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ar^tm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0005182	increased circulating estradiol level	"greater than the normal blood concentration of this most potent naturally occurring estrogen in mammals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Foxo1^tm1Rdp/Foxo1^tm1.1Rdp,Foxo3^tm1Rdp/Foxo3^tm1.1Rdp,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
MP:0005185	decreased circulating progesterone level	"less than the normal blood concentration of this antiestrogenic steroid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66817]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129
MP:0005186	increased circulating progesterone level	"greater than the normal blood concentration of this antiestrogenic steroid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66817]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad4^tm1Rob/Smad4^tm1.1Rob Genetic Background: involves: 129S/SvEv * C57BL/6J
MP:0005324	ascites	"accumulation or retention of fluid within the peritoneal cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Dicer1^tm1Tara/Dicer1^tm1Tara,Pten^tm1Hwu/Pten^tm1Hwu,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Dicer1^tm1Tara/Dicer1^tm1Tara,Pten^tm1Hwu/Pten^tm1Hwu,Trp53^tm2Tyj/Trp53⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Pten^tm1Hwu/Pten^tm1Hwu,Trp53^tm2Tyj/Trp53⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd
MP:0005418	abnormal circulating hormone level	"anomalous blood concentration of any of the chemical substances that have specific regulatory effects on the activity of a certain organ or organs; originally applied to substances secreted by various endocrine glands and transported in the bloodstream to the target organs, it is sometimes extended to include substances that are not produced by the endocrine glands but that have similar effects" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Foxo1^tm1Rdp/Foxo1^tm1.1Rdp,Foxo3^tm1Rdp/Foxo3^tm1.1Rdp,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
MP:0005431	oocyte depletion	"reduced numbers or absence of germ cells in the female" [llw2:Linda Washburn , Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad4^tm1Rob/Smad4^tm1.1Rob Genetic Background: involves: 129S/SvEv * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad2^tm1Cxd/Smad2^tm1.1Mwst,Smad3^tm1Par/Smad3^tm1Zuk Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0005435	hemoperitoneum	"blood in the peritoneal cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:87293]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2.1Rob,Smad5^tm1Huy/Smad5^tm1Huy Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk,Smad9^tm1Jfm/Smad9^tm1Jfm Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6
MP:0006262	testis tumor	"presence of abnormal rapidly proliferating cells in the testis, usually in the form of a distinct mass" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:60034]	Show Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr,Inha^tm1Bay/Inha^tm1Bay Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr,Inha^tm1Bay/Inha⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amh^tm1Bhr/Amh⁺,Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2.1Rob,Smad5^tm1Huy/Smad5^tm1Huy Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺ Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 Allelic Composition: Ctnnb1^tm1Mmt/Ctnnb1⁺,Kras^tm4Tyj/Kras⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0006418	abnormal testis cord formation	"any structural anomaly in the formation of the attachments derived from the primordial seminiferous cords that differentiate into seminiferous tubules in adolescence; defective testis cord formation is most likely to reflect abnormal function of either Sertoli cells or peritubular myoid (PTM) cells which normally cooperate to deposit a layer of basal lamina that defines the edges of individual testis cords" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0008000	ovary tumor	"presence of abnormal rapidly proliferating cells in the ovary, usually in the form of a distinct mass" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2.1Rob,Smad5^tm1Huy/Smad5^tm1Huy Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk,Smad9^tm1Jfm/Smad9^tm1Jfm Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Kit^W-v/Kit^W-v,Trp53^tm1Brn/Trp53^tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/N
MP:0008256	abnormal myometrium morphology	"any structural anomaly of the smooth muscle coat of the uterus, which forms the main mass of the organ and surrounds and supports the endometrium" [MESH:A02.633.570.500, MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0008257	thin myometrium	"reduced thickness of the smooth muscle coat of the uterus, which forms the main mass of the organ and surrounds and supports the endometrium" [MESH:A02.633.570.500, MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129
MP:0008261	arrest of male meiosis	"cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ar^tm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0008803	abnormal placental labyrinth vasculature morphology	"any structural anomaly in blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0008868	abnormal granulosa cell morphology	"any structural anomaly of a supporting cell for the developing female gamete in the ovary of mammals; granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle" [MESH:A.05.360.319.114.630.535.200]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad4^tm1Rob/Smad4^tm1.1Rob Genetic Background: involves: 129S/SvEv * C57BL/6J
MP:0008871	abnormal ovarian follicle number	"abnormal numbers of spheroid cell aggregations in the ovary" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kmt2b^tm1Afst/Kmt2b^tm1.1Afst,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
MP:0008876	decreased uterine NK cell number	"reduced number of the uterine subset of the non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0008877	abnormal DNA methylation	"any anomaly in the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine of DNA" [GO:0006306]	Show Allelic Composition: Kmt2b^tm1Afst/Kmt2b^tm1.1Afst,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
MP:0008959	abnormal spongiotrophoblast cell morphology	"any structural anomaly of a trophoblast cell that arises in the junctional zone of the placenta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0008995	early reproductive senescence	"loss of reproductive capacity occurring at an earlier than expected age" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2.1Rob,Smad5^tm1Huy/Smad5^tm1Huy Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk,Smad9^tm1Jfm/Smad9^tm1Jfm Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6
MP:0009071	short oviduct	"length reduction or truncation of the tube through which the ova pass from the ovary to the uterus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129
MP:0009089	short uterine horn	"length reduction or truncation of either one of the pair of tubular extensions from the uterine body where the uterus and the uterine tubes meet" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0009092	endometrium hyperplasia	"overdevelopment or increased size, usually due an increased number of cells, of the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0009096	decreased endometrial gland number	"fewer than normal numbers of the simple or branched tubular glands found in the mucus membrane of the uterus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129
MP:0009139	failure of Mullerian duct regression	"failure of the transient embryonic paramesonephric ducts, which normally develop into the oviduct, uterus, cervix and upper vagina in the female, to regress in the male; persistence of Mullerian ducts is typically consistent with a loss of anti-Mullerian hormone signaling and may allow development of the female reproductive tract in males" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm2Kem/Ctnnb1^tm2.1Kem Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
MP:0009207	internal male genitalia hypoplasia	"underdevelopment or reduced size of the internal masculine genital organs, usually due to a reduced number of cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0009363	abnormal secondary ovarian follicle morphology	"any structural abnormality in the ovarian follicle in which the primary oocyte attains its full size and is surrounded by an extracellular glycoprotein layer (zona pellucida) that separates it from a peripheral layer of follicular cells permeated by one or more fluid-filled antra; the primary oocyte occupies the cumulus oophorus while the theca of the follicle develops into internal and external layers" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad4^tm1Rob/Smad4^tm1.1Rob Genetic Background: involves: 129S/SvEv * C57BL/6J Allelic Composition: Inhba^tm1Zuk/Inhba^tm3Zuk,Inhbb^tm1Jae/Inhbb^tm1Jae,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad2^tm1Cxd/Smad2^tm1.1Mwst,Smad3^tm1Par/Smad3^tm1Zuk Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0009373	abnormal cumulus expansion	"defective or reduced ability of the cumulus cells to synthesize and accumulate hyaluronan into an extracellular matrix (ECM), which provides an essential microenvironment for oocyte fertilization; this expanded ECM binds the oocyte and the cumulus cells together, protects the oocyte from the proteolytic and mechanical stresses during extrusion, and allows sperm binding, penetration, and fertilization" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad4^tm1Rob/Smad4^tm1.1Rob Genetic Background: involves: 129S/SvEv * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad2^tm1Cxd/Smad2^tm1.1Mwst,Smad3^tm1Par/Smad3^tm1Zuk Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0009374	failure of cumulus expansion	"complete inability of the cumulus cells to secrete an extensive extracellular matrix required for successful fertilization" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad4^tm1Rob/Smad4^tm1.1Rob Genetic Background: involves: 129S/SvEv * C57BL/6J
MP:0009397	increased trophoblast giant cell number	"greater than normal number of cells of the extraembryonic cell layer that contributes to the placenta" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0009433	polyovular ovarian follicle	"an ovarian follicle containing more than one oocyte (ovum)" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Inhba^tm1Zuk/Inhba^tm3Zuk Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
MP:0009444	ovarian follicular cyst	"a sac filled with fluid that may develop when the structure containing the egg fails to break open at the time of ovulation" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr5a1^tm1Klp/Nr5a1^tm2Klp Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
MP:0009592	Leydig cell tumor	"rare testicular tumors of the male gonadal interstitium that are frequently hormonally active, leading to feminizing or virilizing syndromes; Leydig cell tumors comprise 1-3% of all testicular neoplasms, can be pure or mixed with other sex cord-stromal or germ cell tumors, and are usually benign, although malignant variants also occur" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr,Inha^tm1Bay/Inha^tm1Bay Genetic Background: involves: 129S7/SvEvBrd
MP:0009648	abnormal superovulation	"impaired ability of a female to be induced to ovulate an expected number of ova after treatment with specific gonadotrophic hormones" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129
MP:0009661	abnormal pregnancy	"any anomaly in the process of maintaining a developing embryo or fetus within the female body from conception to birth" [ISBN:0198542771 "Rugh, Roberts, The Mouse: Its Reproduction and Development", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Dicer1^tm1Bdh/Dicer1^tm1Bdh Genetic Background: involves: 129 Allelic Composition: Pten^tm1Hwu/Pten^tm1Hwu,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd
MP:0011102	partial embryonic lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Genetic Background: involves: 129S7/SvEvBrd
MP:0011750	abnormal seminiferous tubule epithelium morphology	"any structural anomaly of the stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule" [MGI:csmith]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Stk11^tm1Rdp/Stk11^tm1Rdp Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc1^tm1Djk/Tsc1^tm1Djk Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Tsc2^tm1.1Mjg/Tsc2^tm1.1Mjg Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0012411	increased granulosa cell tumor incidence	"greater than the expected number of neoplasms derived from somatic cells of the sex cord in the ovary a given population in a given time period" [http://orcid.org/0000-0001-5208-3432]	Show Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr,Inha^tm1Bay/Inha^tm1Bay Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Huy Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2.1Rob,Smad5^tm1Huy/Smad5^tm1Huy Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Smad1^tm2Rob/Smad1^tm2Rob,Smad5^tm1Huy/Smad5^tm1Zuk Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ Allelic Composition: Pten^tm1Hwu/Pten^tm1Hwu,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺ Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 Allelic Composition: Ctnnb1^tm1Mmt/Ctnnb1⁺,Kras^tm4Tyj/Kras⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 Allelic Composition: Pten^tm1Hwu/Pten^tm1Hwu,Trp53^tm2Tyj/Trp53⁺,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd Allelic Composition: Foxo1^tm1Rdp/Foxo1^tm1.1Rdp,Foxo3^tm1Rdp/Foxo3^tm1.1Rdp,Amhr2^tm3(cre)Bhr/Amhr2⁺ Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Kit^W-v/Kit^W-v,Trp53^tm1Brn/Trp53^tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/N
MP:0013399	endometrium fibrosis	"invasion of fibrous connective tissue into the endometrium, often resulting from inflammation or injury" [MGI:Anna]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Pten^tm1Hwu/Pten^tm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
MP:0013539	increased ovary adenoma incidence	"greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in the ovary, occurring in a specific population in a given time period" [MGI:Anna]	Show Allelic Composition: Amhr2^tm3(cre)Bhr/Amhr2⁺,Kit^W-v/Kit^W-v,Trp53^tm1Brn/Trp53^tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/N

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr

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