ENSGALG00000003161


Gallus gallus

Features
Gene ID: ENSGALG00000003161
  
Biological name :GDF3
  
Synonyms : embryonic growth/differentiation factor 1 / GDF3
  
Possible biological names infered from orthology : ceramide synthase 1 / CERS1 / GDF1 / growth differentiation factor 1 / growth differentiation factor 3 / P20863 / P27539 / P27544 / P27545 / Q07104 / Q9NR23
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 3758227
Gene end: 3760332
  
Corresponding Affymetrix probe sets: Gga.4324.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004992
NCBI entrez gene - 396132     See in Manteia.
RefSeq - NM_205211
RefSeq Peptide - NP_990542
swissprot - Q98950
Ensembl - ENSGALG00000003161
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gdf3ENSDARG00000037995Danio rerio
 CERS1ENSG00000223802Homo sapiens
 GDF1ENSG00000130283Homo sapiens
 GDF3ENSG00000184344Homo sapiens
 Cers1ENSMUSG00000087408Mus musculus
 Gdf1ENSMUSG00000109523Mus musculus
 Gdf3ENSMUSG00000030117Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
INHBA / inhibin beta A chain precursor / P08476* / Q04998* / Inhibin beta A chain * / inhibin beta A subunit*ENSGALG0000003461621
BMP3 / bone morphogenetic protein 3 precursor / P12645* / Q8BHE5* / Bone morphotic protein 3 * / bone morphogenetic protein 3*ENSGALG0000003505220
GDF10 / growth differentiation factor 10 / P55107* / P97737*ENSGALG0000000598520
TGFB3 / transforming growth factor beta 3 / P10600*ENSGALG0000001034619
BMP15 / bone morphogenetic protein 15 precursor ENSGALG0000000474218
INHBB / inhibin beta B chain precursor / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*ENSGALG0000002877018
GDF9 / growth differentiation factor 9 / O60383* / Q07105*ENSGALG0000002840717
NODAL* / P43021* / Q96S42* / nodal growth differentiation factor*ENSGALG0000000320917
GDF8 / O42220 / Growth/differentiation factor 8 / MSTN* / O08689* / O14793* / myostatin*ENSGALG0000003945817
TGFB2 / P27090* / P61812* / transforming growth factor beta 2* / Transforming growth factor beta-2 Latency-associated peptide*ENSGALG0000000961217
GDF15* / Q99988* / Q9Z0J7* / growth differentiation factor 15* / Mus musculus growth differentiation factor 15 (Gdf15), transcript variant 2, mRNA.*ENSGALG000000462789


Protein motifs (from Interpro)
Interpro ID Name
 IPR001111  TGF-beta, propeptide
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0030509 BMP signaling pathway IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0060395 SMAD protein signal transduction IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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