ENSDARG00000040777


Danio rerio

Features
Gene ID: ENSDARG00000040777
  
Biological name :inhbb
  
Synonyms : inhbb / inhibin, beta B
  
Possible biological names infered from orthology : Inhibin beta B chain / inhibin beta B subunit / P09529 / Q04999
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 36967294
Gene end: 36974879
  
Corresponding Affymetrix probe sets: Dr.473.1.S1_at (Zebrafish Array)   NM_131068_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000059752
NCBI entrez gene - 30275     See in Manteia.
RefSeq - NM_131068
RefSeq Peptide - NP_571143
swissprot - B0S7E0
ZFIN ID - ZDB-GENE-990415-2
Ensembl - ENSDARG00000040777
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 INHBBENSGALG00000028770Gallus gallus
 INHBBENSG00000163083Homo sapiens
 InhbbENSMUSG00000037035Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CABZ01074203.1 / INHBB* / P09529* / inhibin beta B subunit*ENSDARG0000010389253
inhbaa / inhibin, beta Aa / INHBA* / P08476* / inhibin beta A subunit*ENSDARG0000001267142
inhbab / inhibin, beta Ab / INHBA* / P08476* / inhibin beta A subunit*ENSDARG0000002475942
INHBE / inhibin beta E subunit / INHBC* / P58166* / P55103* / inhibin beta C subunit*ENSDARG0000010098634
gdf11 / growth differentiation factor 11 / O95390* / Q9Z1W4*ENSDARG0000004492421
mstnb / O42222 / myostatin b / MSTN* / O08689* / O14793* / myostatin*ENSDARG0000006913321
mstna / myostatin a / MSTN* / O14793* / O08689* / myostatin*ENSDARG0000004294720
tgfb3 / transforming growth factor, beta 3 / P10600*ENSDARG0000001936720
tgfb2 / transforming growth factor, beta 2 / P27090* / P61812* / Transforming growth factor beta-2 Latency-associated peptide*ENSDARG0000002708719
tgfb2l / transforming growth factor, beta 2, likeENSDARG0000007187919
ndr1 / nodal-related 1 / NODAL* / Q96S42* / P43021* / nodal growth differentiation factor*ENSDARG0000005709618
tgfb1b / transforming growth factor, beta 1b / TGFB1* / P04202* / P01137* / transforming growth factor beta 1*ENSDARG0000003489518
tgfb1a / transforming growth factor, beta 1a / TGFB1* / P01137* / transforming growth factor beta 1*ENSDARG0000004150218
gdf3 / P35621 / growth differentiation factor 3 / GDF1* / CERS1* / Q9NR23* / P27544* / P27545* / Q07104* / P20863* / P27539* / ceramide synthase 1* / growth differentiation factor 1* / Embr...ENSDARG0000003799517
gdf10a / growth differentiation factor 10a / GDF10* / P97737* / P55107* / growth differentiation factor 10*ENSDARG0000009537817
spaw / southpaw / NODAL* / P43021* / Q96S42* / nodal growth differentiation factor*ENSDARG0000001430916
gdf10b / growth differentiation factor 10b / GDF10* / P97737* / P55107* / growth differentiation factor 10*ENSDARG0000007389116
bmp3 / bone morphogenetic protein 3 / P12645* / Q8BHE5* / Bone morphotic protein 3 *ENSDARG0000006052615
ndr2 / nodal-related 2 / NODAL* / Q96S42* / nodal growth differentiation factor*ENSDARG0000010127914
bmp15 / bone morphogenetic protein 15ENSDARG0000003749112


Protein motifs (from Interpro)
Interpro ID Name
 IPR000381  Inhibin, beta B subunit
 IPR001111  TGF-beta, propeptide
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0060395 SMAD protein signal transduction IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Signaling by Activin
Glycoprotein hormones
Antagonism of Activin by Follistatin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018968 acvr1ba / activin A receptor type 1Ba / Q61271* / ACVR1B* / P36896* / Activin receptor type-1B * / activin A receptor type 1B*  / complex / reaction
 ENSDARG00000052846 fsta / Q9YHV4 / follistatin a / FST* / P19883* / follistatin* / follistatin FST315 *  / complex / reaction
 ENSDARG00000052142 acvr1bb / activin A receptor type 1Bb / Q61271* / ACVR1B* / P36896* / Activin receptor type-1B * / activin A receptor type 1B*  / complex / reaction
 ENSDARG00000052433 inha / inhibin, alpha / P05111* / inhibin alpha subunit*  / complex
 ENSDARG00000104700 acvr2ab / activin A receptor type 2Ab / ACVR2A* / P27037* / activin A receptor type 2A*  / complex / reaction
 ENSDARG00000011188 acvr2aa / activin A receptor type 2Aa / P27038* / ACVR2A* / P27037* / Activin receptor type-2A * / activin A receptor type 2A*  / complex / reaction
 ENSDARG00000044422 acvr2ba / activin A receptor type 2Ba / Q13705* / ACVR2B* / P27040* / Activin receptor type-2B * / activin A receptor type 2B*  / reaction / complex
 ENSDARG00000040777 inhbb / inhibin, beta B / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*  / complex
 ENSDARG00000012671 inhbaa / inhibin, beta Aa / INHBA* / P08476* / inhibin beta A subunit*  / complex
 ENSDARG00000103892 CABZ01074203.1 / INHBB* / P09529* / inhibin beta B subunit*  / complex
 ENSDARG00000103108 acvr2bb / activin A receptor type 2Bb / ACVR2B* / Q13705* / activin A receptor type 2B*  / reaction / complex
 ENSDARG00000057992 fstb / follistatin b / FST* / P19883* / follistatin* / follistatin FST315 *  / reaction / complex
 ENSDARG00000086172 ACVR1C / activin A receptor type 1C / Q8NER5*  / complex
 ENSDARG00000025670 fstl3 / follistatin-like 3 (secreted glycoprotein) / Q9EQC7* / O95633* / follistatin like 3* / Follistatin-related protein 3 *  / reaction / complex






 

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