ENSDARG00000042947


Danio rerio

Features
Gene ID: ENSDARG00000042947
  
Biological name :mstna
  
Synonyms : mstna / myostatin a
  
Possible biological names infered from orthology : MSTN / myostatin / O08689 / O14793
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 12790837
Gene end: 12795340
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000063054
NCBI entrez gene - 445816     See in Manteia.
swissprot - Q68IN2
ZFIN ID - ZDB-GENE-050208-735
Ensembl - ENSDARG00000042947
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GDF8ENSGALG00000039458Gallus gallus
 MSTNENSG00000138379Homo sapiens
 MstnENSMUSG00000026100Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mstnb / O42222 / myostatin b / MSTN* / O08689* / O14793* / myostatin*ENSDARG0000006913367
gdf11 / growth differentiation factor 11 / O95390* / Q9Z1W4*ENSDARG0000004492460
tgfb3 / transforming growth factor, beta 3 / P10600*ENSDARG0000001936725
tgfb2 / transforming growth factor, beta 2 / P27090* / P61812* / Transforming growth factor beta-2 Latency-associated peptide*ENSDARG0000002708723
tgfb2l / transforming growth factor, beta 2, likeENSDARG0000007187922
tgfb1b / transforming growth factor, beta 1b / TGFB1* / P04202* / P01137* / transforming growth factor beta 1*ENSDARG0000003489522
tgfb1a / transforming growth factor, beta 1a / TGFB1* / P01137* / transforming growth factor beta 1*ENSDARG0000004150222
inhbab / inhibin, beta Ab / INHBA* / P08476* / inhibin beta A subunit*ENSDARG0000002475922
inhbb / inhibin, beta B / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*ENSDARG0000004077721
inhbaa / inhibin, beta Aa / INHBA* / P08476* / inhibin beta A subunit*ENSDARG0000001267120
gdf3 / P35621 / growth differentiation factor 3 / GDF1* / CERS1* / Q9NR23* / P27544* / P27545* / Q07104* / P20863* / P27539* / ceramide synthase 1* / growth differentiation factor 1* / Embr...ENSDARG0000003799519
INHBE / inhibin beta E subunit / INHBC* / P58166* / P55103* / inhibin beta C subunit*ENSDARG0000010098618
gdf10a / growth differentiation factor 10a / GDF10* / P97737* / P55107* / growth differentiation factor 10*ENSDARG0000009537817
gdf10b / growth differentiation factor 10b / GDF10* / P97737* / P55107* / growth differentiation factor 10*ENSDARG0000007389117
CABZ01074203.1 / INHBB* / P09529* / inhibin beta B subunit*ENSDARG0000010389217
bmp3 / bone morphogenetic protein 3 / P12645* / Q8BHE5* / Bone morphotic protein 3 *ENSDARG0000006052617
spaw / southpaw / NODAL* / P43021* / Q96S42* / nodal growth differentiation factor*ENSDARG0000001430916
ndr2 / nodal-related 2 / NODAL* / Q96S42* / nodal growth differentiation factor*ENSDARG0000010127916
gdf9 / growth differentiation factor 9 / O60383* / Q07105*ENSDARG0000000322914
ndr1 / nodal-related 1 / NODAL* / Q96S42* / P43021* / nodal growth differentiation factor*ENSDARG0000005709614


Protein motifs (from Interpro)
Interpro ID Name
 IPR001111  TGF-beta, propeptide
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR015616  Growth/differentiation factor 8
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0060395 SMAD protein signal transduction IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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