ENSDARG00000037491


Danio rerio

Features
Gene ID: ENSDARG00000037491
  
Biological name :bmp15
  
Synonyms : bmp15 / bone morphogenetic protein 15
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 51768343
Gene end: 51775688
  
Corresponding Affymetrix probe sets: Dr.7003.1.A1_at (Zebrafish Array)   Dr.7003.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000054590
Ensembl peptide - ENSDARP00000124690
swissprot - F1QA78
swissprot - F8W2L1
ZFIN ID - ZDB-GENE-030131-6115
Ensembl - ENSDARG00000037491
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BMP15ENSGALG00000004742Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gdf9 / growth differentiation factor 9 / O60383* / Q07105*ENSDARG0000000322922
bmp3 / bone morphogenetic protein 3 / P12645* / Q8BHE5* / Bone morphotic protein 3 *ENSDARG0000006052617
gdf10b / growth differentiation factor 10b / GDF10* / P97737* / P55107* / growth differentiation factor 10*ENSDARG0000007389116
gdf3 / P35621 / growth differentiation factor 3 / GDF1* / CERS1* / Q9NR23* / P27544* / P27545* / Q07104* / P20863* / P27539* / ceramide synthase 1* / growth differentiation factor 1* / Embr...ENSDARG0000003799516
gdf10a / growth differentiation factor 10a / GDF10* / P97737* / P55107* / growth differentiation factor 10*ENSDARG0000009537816
ndr1 / nodal-related 1 / NODAL* / Q96S42* / P43021* / nodal growth differentiation factor*ENSDARG0000005709615
spaw / southpaw / NODAL* / P43021* / Q96S42* / nodal growth differentiation factor*ENSDARG0000001430915
tgfb2 / transforming growth factor, beta 2 / P27090* / P61812* / Transforming growth factor beta-2 Latency-associated peptide*ENSDARG0000002708715
ndr2 / nodal-related 2 / NODAL* / Q96S42* / nodal growth differentiation factor*ENSDARG0000010127915
inhbab / inhibin, beta Ab / INHBA* / P08476* / inhibin beta A subunit*ENSDARG0000002475915
tgfb2l / transforming growth factor, beta 2, likeENSDARG0000007187914
tgfb3 / transforming growth factor, beta 3 / P10600*ENSDARG0000001936714
inhbaa / inhibin, beta Aa / INHBA* / P08476* / inhibin beta A subunit*ENSDARG0000001267114
inhbb / inhibin, beta B / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*ENSDARG0000004077713
INHBE / inhibin beta E subunit / INHBC* / P58166* / P55103* / inhibin beta C subunit*ENSDARG0000010098613
mstna / myostatin a / MSTN* / O14793* / O08689* / myostatin*ENSDARG0000004294713
tgfb1a / transforming growth factor, beta 1a / TGFB1* / P01137* / transforming growth factor beta 1*ENSDARG0000004150213
tgfb1b / transforming growth factor, beta 1b / TGFB1* / P04202* / P01137* / transforming growth factor beta 1*ENSDARG0000003489513
CABZ01074203.1 / INHBB* / P09529* / inhibin beta B subunit*ENSDARG0000010389212
mstnb / O42222 / myostatin b / MSTN* / O08689* / O14793* / myostatin*ENSDARG0000006913312


Protein motifs (from Interpro)
Interpro ID Name
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR015923  Bone morphogenetic protein 15
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001541 ovarian follicle development IEA
 biological_processGO:0001556 oocyte maturation IMP
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0046660 female sex differentiation IMP
 biological_processGO:0060016 granulosa cell development IEA
 biological_processGO:0060283 negative regulation of oocyte development IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000303 female organism female organism male , abnormal
female organism has extra parts of type spermatocyte , abnormal
female organism has extra parts of type sperm , abnormal
female organism has extra parts of type spermatogonium , abnormal
female organism male gamete generation increased occurrence , abnormal
Show

 ZFA:0000403 ovary ovary granulosa cell absent , abnormal
Show

 ZFA:0001109 oocyte oocyte maturity , abnormal
oocyte decreased amount , abnormal
oocyte degeneration , abnormal
Show

 ZFA:0001110 ovarian follicle ovarian follicle maturity , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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