ENSDARG00000055659


Danio rerio

Features
Gene ID: ENSDARG00000055659
  
Biological name :gpr161
  
Synonyms : gpr161 / G protein-coupled receptor 161 / Q90X46
  
Possible biological names infered from orthology : B2RPY5 / Q8N6U8
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 34148714
Gene end: 34162374
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000072514
Ensembl peptide - ENSDARP00000118097
NCBI entrez gene - 368421     See in Manteia.
RefSeq - NM_001007199
RefSeq Peptide - NP_001007200
swissprot - Q90X46
ZFIN ID - ZDB-GENE-030616-58
Ensembl - ENSDARG00000055659
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GPR161ENSGALG00000015247Gallus gallus
 GPR161ENSG00000143147Homo sapiens
 B2RPY5ENSMUSG00000040836Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:ch211-237c6.4 / B2RPY5* / GPR161* / Q8N6U8* / G protein-coupled receptor 161*ENSDARG0000005890367
gpr101 / G protein-coupled receptor 101 / Q80T62* / Q96P66*ENSDARG0000003921820
BX324188.1ENSDARG0000007597018
GPR45 / si:dkeyp-118h3.5 / Q9EQQ4* / Q9Y5Y3* / G protein-coupled receptor 45* / Probable G-protein coupled receptor 45 *ENSDARG0000006335715
gpr63 / G protein-coupled receptor 63 / Q9BZJ6* / Q9EQQ3* / Probable G-protein coupled receptor 63 *ENSDARG0000007454013


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0030819 obsolete positive regulation of cAMP biosynthetic process ISS
 biological_processGO:0051924 regulation of calcium ion transport IMP
 biological_processGO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005929 cilium ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0055037 recycling endosome ISS
 cellular_componentGO:0060170 ciliary membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity ISS


Pathways (from Reactome)
Pathway description
Hedgehog off state
Hedgehog on state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle orientation atrium , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000101 diencephalon diencephalon morphology , abnormal
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 ZFA:0000115 heart rudiment heart rudiment morphology , abnormal
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 ZFA:0000123 liver liver mislocalised , abnormal
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 ZFA:0000360 heart tube heart tube morphology , abnormal
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 ZFA:0001390 pancreatic bud pancreatic bud mislocalised , abnormal
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 ZFA:0005041 anterior lateral plate mesoderm anterior lateral plate mesoderm morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000012368 ttc21b / tetratricopeptide repeat domain 21B / Q0HA38* / Q7Z4L5*  / reaction / complex
 ENSDARG00000069269 wdr35 / WD repeat domain 35 / Q8BND3* / Q9P2L0*  / complex / reaction
 ENSDARG00000063672 zmp:0000000711 / TULP3* / O75386* / tubby like protein 3*  / complex / reaction
 ENSDARG00000037406 wdr19 / WD repeat domain 19 / Q3UGF1* / Q8NEZ3*  / reaction / complex
 ENSDARG00000031886 ift140 / intraflagellar transport 140 homolog (Chlamydomonas) / E9PY46* / Q96RY7* / Intraflagellar transport * / intraflagellar transport 140*  / complex / reaction






 

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