ENSDARG00000069269


Danio rerio

Features
Gene ID: ENSDARG00000069269
  
Biological name :wdr35
  
Synonyms : wdr35 / WD repeat domain 35
  
Possible biological names infered from orthology : Q8BND3 / Q9P2L0
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 32580382
Gene end: 32626247
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000091436
Ensembl peptide - ENSDARP00000119956
NCBI entrez gene - 565515     See in Manteia.
RefSeq - NM_001145589
RefSeq Peptide - NP_001139061
swissprot - F1R7T0
swissprot - B7ZD88
ZFIN ID - ZDB-GENE-060810-148
Ensembl - ENSDARG00000069269
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000016477Gallus gallus
 ENSGALG00000038544Gallus gallus
 WDR35ENSG00000118965Homo sapiens
 Wdr35ENSMUSG00000066643Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tulp4a / tubby like protein 4a / TULP4* / Q9JIL5* / Q9NRJ4* / tubby like protein 4*ENSDARG0000004591111
tulp4b / tubby like protein 4b / TULP4* / Q9JIL5* / Q9NRJ4* / tubby like protein 4*ENSDARG0000006305611
zmp:0000000711 / TULP3* / O75386* / tubby like protein 3*ENSDARG000000636729
tub / tubby bipartite transcription factor / P50586* / P50607*ENSDARG000000621658
tulp1a / tubby like protein 1a / TULP1* / O00294* / Q9Z273* / tubby like protein 1*ENSDARG000000752957
tulp1b / tubby like protein 1b / TULP1* / O00294* / Q9Z273* / tubby like protein 1*ENSDARG000000782107
si:dkey-220f10.4 / TULP2* / O00295* / P46686* / tubby like protein 2*ENSDARG000000629027


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017233  WD repeat protein 35
 IPR017986  WD40-repeat-containing domain
 IPR024977  Anaphase-promoting complex subunit 4, WD40 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0035721 intraciliary retrograde transport IEA
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0061512 protein localization to cilium IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0030991 intraciliary transport particle A IEA
 cellular_componentGO:0036064 ciliary basal body IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IBA


Pathways (from Reactome)
Pathway description
Hedgehog off state
Intraflagellar transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009367 neuromast hair cell neuromast hair cell decreased amount , ameliorated
neuromast hair cell kinocilium absent , abnormal
neuromast hair cell import across plasma membrane process efficacy , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000058903 si:ch211-237c6.4 / B2RPY5* / GPR161* / Q8N6U8* / G protein-coupled receptor 161*  / reaction / complex
 ENSDARG00000012368 ttc21b / tetratricopeptide repeat domain 21B / Q0HA38* / Q7Z4L5*  / complex
 ENSDARG00000031886 ift140 / intraflagellar transport 140 homolog (Chlamydomonas) / E9PY46* / Q96RY7* / Intraflagellar transport * / intraflagellar transport 140*  / complex
 ENSDARG00000037406 wdr19 / WD repeat domain 19 / Q3UGF1* / Q8NEZ3*  / complex
 ENSDARG00000055659 gpr161 / Q90X46 / G protein-coupled receptor 161 / B2RPY5* / Q8N6U8*  / reaction / complex
 ENSDARG00000063672 zmp:0000000711 / TULP3* / O75386* / tubby like protein 3*  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr