Manteia

ENSDARG00000055715

Danio rerio

Features

Gene ID:	ENSDARG00000055715

Biological name :	capn8

Synonyms :	calpain 8 / capn8

Possible biological names infered from orthology :	A6NHC0 / Q91VA3

Species:	Danio rerio

Chr. number:	22
Strand:	1
Band:
Gene start:	26400519
Gene end:	26435494

Corresponding Affymetrix probe sets:	Dr.22670.1.A1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000122183 Ensembl peptide - ENSDARP00000135623 NCBI entrez gene - 337730 See in Manteia. RefSeq - NM_001244080 RefSeq Peptide - NP_001231009 swissprot - A5WWC4 swissprot - A0A0R4IK45 ZFIN ID - ZDB-GENE-050522-279 Ensembl - ENSDARG00000055715

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
CAPN8	ENSGALG00000009382	Gallus gallus
CAPN8	ENSG00000203697	Homo sapiens
Capn8	ENSMUSG00000038599	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
zgc:92480 / CAPN2* / P17655* / calpain 2*	ENSDARG00000034211	62
capn1a / calpain 1, (mu/I) large subunit a / CAPN11* / Q6J756* / Q9UMQ6* / calpain 11*	ENSDARG00000052702	61
zgc:55262 / CAPN1* / O35350* / P07384* / calpain 1* / Calpain-1 catalytic subunit *	ENSDARG00000045199	60
capn2a / calpain 2, (m/II) large subunit a / CAPN2* / P17655* / O08529* / calpain 2* / Calpain-2 catalytic subunit *	ENSDARG00000091699	60
capn1b / calpain 1, (mu/I) large subunit b / CAPN11* / Q6J756* / Q9UMQ6* / calpain 11*	ENSDARG00000052748	59
CAPN1 / si:dkeyp-50d11.2 / O35350* / P07384* / calpain 1* / Calpain-1 catalytic subunit *	ENSDARG00000055338	59
capn2b / calpain 2, (m/II) large subunit b / CAPN2* / P17655* / O08529* / calpain 2* / Calpain-2 catalytic subunit *	ENSDARG00000055592	57
capn3a / calpain 3a, (p94) / CAPN3* / P20807* / calpain 3*	ENSDARG00000041864	53
capn9 / calpain 9 / O14815* / Q9D805*	ENSDARG00000012341	50
capn3b / calpain 3b / CAPN3* / P20807* / Q64691* / calpain 3*	ENSDARG00000043035	49
capn12 / calpain 12 / Q6ZSI9*	ENSDARG00000010758	38
zgc:136872 / A8MX76* / CAPN14* / CAPN13* / Q3UW68* / Q6MZZ7* / calpain 14* / calpain 13*	ENSDARG00000008553	36
si:ch211-202f3.3 / A8MX76* / CAPN14* / CAPN13* / Q3UW68* / Q6MZZ7* / calpain 14* / calpain 13*	ENSDARG00000052917	36
zgc:85932	ENSDARG00000098239	35
capn5b / calpain 5b / CAPN5* / O08688* / O15484* / calpain 5*	ENSDARG00000069748	32
capn5a / calpain 5a / CAPN5* / O08688* / O15484* / calpain 5*	ENSDARG00000103317	31
si:dkey-19b23.13	ENSDARG00000061850	31
zgc:162184 / A8MX76* / CAPN14* / CAPN13* / Q3UW68* / Q6MZZ7* / calpain 14* / calpain 13*	ENSDARG00000077217	29
si:ch211-202f3.4 / A8MX76* / CAPN14* / CAPN13* / Q3UW68* / Q6MZZ7* / calpain 14* / calpain 13*	ENSDARG00000091723	28

Protein motifs (from Interpro)

Interpro ID	Name
IPR000169	Cysteine peptidase, cysteine active site
IPR001300	Peptidase C2, calpain, catalytic domain
IPR002048	EF-hand domain
IPR011992	EF-hand domain pair
IPR018247	EF-Hand 1, calcium-binding site
IPR022682	Peptidase C2, calpain, large subunit, domain III
IPR022683	Peptidase C2, calpain, domain III
IPR022684	Peptidase C2, calpain family
IPR033883	Calpain subdomain III

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006508	proteolysis	IEA
biological_process	GO:0051493	regulation of cytoskeleton organization	IEA
cellular_component	GO:0005622	intracellular	IEA
molecular_function	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	IEA
molecular_function	GO:0005509	calcium ion binding	IEA
molecular_function	GO:0008233	peptidase activity	IEA
molecular_function	GO:0008234	cysteine-type peptidase activity	IEA
molecular_function	GO:0016787	hydrolase activity	IEA

Pathways (from Reactome)

Pathway description

Degradation of the extracellular matrix

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr