ENSDARG00000055338


Danio rerio

Features
Gene ID: ENSDARG00000055338
  
Biological name :CAPN1
  
Synonyms : CAPN1 / si:dkeyp-50d11.2
  
Possible biological names infered from orthology : calpain 1 / Calpain-1 catalytic subunit / O35350 / P07384
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 27482149
Gene end: 27507786
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000143925
Ensembl peptide - ENSDARP00000072123
Ensembl peptide - ENSDARP00000146759
Ensembl peptide - ENSDARP00000152398
NCBI entrez gene - 565825     See in Manteia.
swissprot - E9QFN0
ZFIN ID - ZDB-GENE-091113-22
Ensembl - ENSDARG00000055338
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CAPN1ENSG00000014216Homo sapiens
 Capn1ENSMUSG00000024942Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:55262 / CAPN1* / O35350* / P07384* / calpain 1* / Calpain-1 catalytic subunit *ENSDARG0000004519977
capn1a / calpain 1, (mu/I) large subunit a / CAPN11* / Q6J756* / Q9UMQ6* / calpain 11*ENSDARG0000005270266
capn1b / calpain 1, (mu/I) large subunit b / CAPN11* / Q6J756* / Q9UMQ6* / calpain 11*ENSDARG0000005274864
zgc:92480 / CAPN2* / P17655* / calpain 2*ENSDARG0000003421163
capn2a / calpain 2, (m/II) large subunit a / CAPN2* / P17655* / O08529* / calpain 2* / Calpain-2 catalytic subunit *ENSDARG0000009169960
capn2b / calpain 2, (m/II) large subunit b / CAPN2* / P17655* / O08529* / calpain 2* / Calpain-2 catalytic subunit *ENSDARG0000005559260
capn8 / calpain 8 / A6NHC0*ENSDARG0000005571559
capn9 / calpain 9 / O14815* / Q9D805*ENSDARG0000001234152
capn3a / calpain 3a, (p94) / CAPN3* / P20807* / calpain 3*ENSDARG0000004186452
capn3b / calpain 3b / CAPN3* / P20807* / Q64691* / calpain 3*ENSDARG0000004303548
capn12 / calpain 12 / Q6ZSI9*ENSDARG0000001075838
zgc:136872 / A8MX76* / CAPN14* / CAPN13* / Q3UW68* / Q6MZZ7* / calpain 14* / calpain 13*ENSDARG0000000855336
si:ch211-202f3.3 / A8MX76* / CAPN14* / CAPN13* / Q3UW68* / Q6MZZ7* / calpain 14* / calpain 13*ENSDARG0000005291736
zgc:85932ENSDARG0000009823934
capn5b / calpain 5b / CAPN5* / O08688* / O15484* / calpain 5*ENSDARG0000006974833
capn5a / calpain 5a / CAPN5* / O08688* / O15484* / calpain 5*ENSDARG0000010331733
si:dkey-19b23.13ENSDARG0000006185031
zgc:162184 / A8MX76* / CAPN14* / CAPN13* / Q3UW68* / Q6MZZ7* / calpain 14* / calpain 13*ENSDARG0000007721728
si:ch211-202f3.4 / A8MX76* / CAPN14* / CAPN13* / Q3UW68* / Q6MZZ7* / calpain 14* / calpain 13*ENSDARG0000009172327


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR001300  Peptidase C2, calpain, catalytic domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR022682  Peptidase C2, calpain, large subunit, domain III
 IPR022683  Peptidase C2, calpain, domain III
 IPR022684  Peptidase C2, calpain family
 IPR033883  Calpain subdomain III


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000013804 capns1b / calpain, small subunit 1 b / Q9D7J7* / CAPNS1* / CAPNS2* / P04632* / Q96L46* / calpain small subunit 2* / calpain small subunit 1*  / complex
 ENSDARG00000035329 capns1a / calpain, small subunit 1 a / Q9D7J7* / CAPNS1* / CAPNS2* / P04632* / Q96L46* / calpain small subunit 2* / calpain small subunit 1*  / complex






 

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